Baseline Renal Dysfunction in Acute Ischemic Stroke Patients: Prevalence and Impact on Early Mortality.

Mahmoud., MedhatI.; Badawy., AhmedE.; Shehta, Nahed; Ramadan, Bothina M.

doi:10.21474/ijar01/2774

Cited by 1 publication

(3 citation statements)

References 26 publications

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“…The majority of patients had ischemic stroke (72.5%) while 27.5% had hemorrhagic stroke. A similar study by Mahmoud M et al 18 shows comparable results.…”

Section: Discussionsupporting

confidence: 70%

“…In a study by Pereg D et al, 15 around 10.4% patients had unrecognized renal dysfunction similar to our study. Mahmood et al 18 founded that 30.2% had renal dysfunction (eGFR < than 60 ml/min/1.73 m2) which was high. Presence of baseline renal dysfunction was recorded as an independent predictor of early mortality in the setting of acute ischemic stroke beside other well-known prognostic factors.…”

Section: Discussionmentioning

confidence: 99%

“…But, there was a significant difference in severe NIHSS score in AKI and Non-AKI patients (P-value=0.0209). Mahmud et al 18 showed that the stroke severity (NIHSS) was higher in those with impaired than those with normal renal function (13.4±1.42, 8.98±2.75 respectively. Patients with severe stroke at presentation are often at increased risk of dehydration as they have a reduced level of consciousness, are physically dependent, unable to communicate, have difficulties in swallowing and decreased oral intake which may predispose them to acute kidney injury.…”

Section: Discussionmentioning

confidence: 99%

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Assessment and Prognostic significance of renal dysfunction in acute stroke patients

Sardana¹,

Jain²

2021

IJN

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During hospitalization due to stroke, patients can have acute kidney injury (AKI) as a possible complication which is frequently overlooked and underestimated in clinical trials. Aims: To assess the prevalence of renal dysfunction in acute stroke patients and to assess its prognostic significance Design, Methods and Materials: A total of 100 patients were recruited for this study with diagnosis of stroke. Renal dysfunction was evaluated in the form of Acute kidney injury and unrecognized renal dysfunction (Baseline Normal serum Creatnine<1.2 mg/dl with EGFR< 60 ml/min on admission). The primary functional outcome was measured using the modified Rankin Scale at the time of discharge, 1 month after stroke onset. Statistical analysis: Analysis of data was done using SPSS-17.Independent t-test and chi-square test were used to calculate difference between two groups Results: Our study shows prevalence of acute kidney injury in patients of stroke is 15%. Moreover, the study showed that AKI after stroke was associated with higher in-hospital mortality and poorer functional outcome at 1 month. Conclusions: Acute kidney injury appears to be a common complication after stroke and is related to increased mortality and disability in stroke. Key Messages: AKI is common complication after stroke and frequent cause of poor functional outcome.

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“…The majority of patients had ischemic stroke (72.5%) while 27.5% had hemorrhagic stroke. A similar study by Mahmoud M et al 18 shows comparable results.…”

Section: Discussionsupporting

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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