Basaloid Squamous Cell Carcinoma of the Larynx: Report of a Case

Abstract

Basaloid squamous cell carcinoma is a variant of squamous cell carcinoma. This malignancy has a predilection fo r the upper aerodiges tive tract, although it has been fo und in multiple other sites. The tumor is highly aggressive biologically, and the overall prognosis is poor despite intensive treatment. We describe a case ofbasaloid squamous cell carcinoma ofthe larynx that metastasized to the spine.

The basaloid variant of squamous cell carcinoma of the larynx

“…There are some studies that reported predilection for the supraglottic subsite. 4 , 7 In the present study, the frequencies of supraglottic and glottic involvement were equal which is contradictory to those previous reports. The patients with BSCC usually present at more advanced stages (stage III&IV).…”

“… 12 In a study by Erdamar et al, 3-year survival rates were 50% and 72% for BSCC and SCC groups. 7 These two studies reports survival rates of BSCC cases located at different parts of UADT. In contrast, Luna et al compared 6 BSCC cases with 47 classical variant SCC cases of the pyriform sinus and found no survival difference.…”

Basaloid squamous cell carcinoma of the head and neck: report of 18 cases

“…Most of our patients presented with advanced stage disease, according to the guidelines established by the UICC. Similarly, previously reported cases of basaloid SCC have primarily presented at an advanced stage, with frequent metastasis 1 , 6 , 8 , 13 , 15 , 24 , 31 …”