Basaloid follicular hamartoma: Solitary and multiple types

A Case of Basaloid Follicular Hamartoma

“…BFH may have no atypical cellular features or mitotic activity, and there may not be a cleft between the tumor cells and surrounding stroma [3][4][5]7 .…”

Multiple Hereditary Infundibulocystic Basal Cell Carcinomas

“…[30][31][32][33][34] In our opinion, some of the cases reported as basaloid follicular hamartoma are better interpreted as trichoepitheliomas, [35][36][37] basal cell carcinoma of fibroepithelioma (Pinkus) type, 38 or infundibulocystic basal cell carcinomas. 11,39 Conversely, some cases reported as trichoepitheliomas are in our opinion examples of basaloid follicular hamartomas. 40,41 Finally, some patients with myasthenia gravis seem to have multiple trichoepitheliomas and basaloid follicular hamartomas, 23 supporting the notion that multiple follicular neoplasms and hamartomas may be cutaneous markers of a more complex familial syndrome.…”

“…Furthermore, 1 specimen from patient 2, family 1, showed combined features of a large nodular basal cell carcinoma, which ulcerated the epidermis, and infundibulocystic basal cell carcinoma. The main controversial point of infundibulocystic basal cell carcinoma is its differential diagnosis with trichoepithelioma, 2-9 basaloid follicular hamartoma, [11][12][13] and folliculocentric basaloid proliferation. 20 10 have established clear-cut histopathologic criteria for differential diagnosis between infundibulocystic basal cell carcinoma and trichoepithelioma.…”

“…More recently, debate has ensued again as to whether this infundibulocystic basal cell carcinoma and basaloid follicular hamartoma are the same or different entities. [11][12][13] We herein describe 2 families in which several members have multiple infundibulocystic basal cell carcinomas. None of the patients had palmar pits or jaw cysts.…”

A neglected basal cell carcinoma in a young patient: successful treatment with immunocryosurgery

“…14 A linear unilateral BFH 15 would be the most relevant latter diagnosis for this patient as it presents as a solitary plaque in a limited, mosaic pattern on the scalp and face. 16 Additionally the diagnosis of BFH was not supported by the histology (Figure 2); the basaloid tumor cell nests in this case extended relatively deeply into the interfollicular dermis and were not confined to the superficial dermis layers as is typical for BFH. 17 Notably, although a very uncommon event, we cannot completely exclude the possibility that the present BCC arose out of a preexisting, meanwhile completely ablated BFH lesion.…”