Basal Cell Carcinoma Arising 57 Years after Interstitial Radiotherapy of a Nasal Hemangioma

Weiss, Elliot; Sukal, Sean A.; Zimbler, Marc S.; Geronemus, Roy G.

doi:10.1111/j.1524-4725.2008.34229.x

Cited by 3 publications

(3 citation statements)

References 21 publications

(27 reference statements)

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“…To the best of our knowledge, no prospective studies have specifically examined the development of NMSC in cohorts of children treated with radiation for infantile hemangiomas. However, there have been individual reports of the development of one or more BCCs at the site of previously irradiated infantile hemangiomas 5 . Our report represents the longest interval reported between irradiation and the development of an NMSC, 70 years.…”

Section: Discussionmentioning

confidence: 71%

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Basal cell carcinoma arising at the site of a previously irradiated infantile hemangioma

Donohue

Salusti‐Simpson

Bombardier

et al. 2023

Pediatric Dermatology

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We describe a case of a previously irradiated infantile hemangioma in a patient 1 year of age. At the age of 71, the patient presented with a pink, pearly plaque at the previously irradiated infantile hemangioma site and was found to have a nodular basal cell carcinoma. This case highlights the rare, but long‐term risks of radiation therapy for hemangiomas, but also presents an interesting historical vignette in dermatological treatments, with photographic documentation. It also represents the longest time interval between irradiation of an infantile hemangioma and the development of a basal cell skin cancer, 70 years in this case.

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Section: Discussionmentioning

confidence: 71%

“…However, there have been individual reports of the development of one or more BCCs at the site of previously irradiated infantile hemangiomas. 5 Our report represents the longest interval reported between irradiation and the development of an NMSC, 70 years.…”

Section: Discussionmentioning

confidence: 72%

Basal cell carcinoma arising at the site of a previously irradiated infantile hemangioma

Donohue

Salusti‐Simpson

Bombardier

et al. 2023

Pediatric Dermatology

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“…Die Ergebnisse hinsichtlich der Hämangiomrückbildung waren umso besser, je früher die Bestrahlung durchgeführt wurde. Die Strahlenschäden wurden jedoch erst Jahre später sichtbar, sodass [55] die Methode erst in den letzten Jahrzehnten des 20. Jahrhunderts aufgegeben wurde [56].…”

Section: Vincristin / Cyclophosphamidunclassified

Überblick der Therapiemöglichkeiten im Management von Säuglingshämangiomen

Krause

Haß²,

Kroker³

et al. 2010

Zentralbl Chir

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The necessity of haemangioma treatment in infants has been controversially discussed for years. One reason is the favoured clinical observation of a potential spontaneous involution without any therapeutic approach or medical treatment, thus avoiding their specific risks. On the other hand, there are several reports on serious cases with -rapidly growing haemangiomas including severe consequences. There are potential complications such as loss of visus in cases of periorbital manifestation. A basic problem is the lack of a unique systematic classification, on the basis of which -diagnostic measures, therapeutic indications and modes could be compared. Such a classification would be much more competent including a sufficient comparison of treatment results. The basic aim in management is to achieve control of the haemangioma growth and induction of its sub-sequent involution back to only a cosmetic detraction. Each threatening functional loss can be classified as an urgent indication for treatment. There is a need to consider the treatment options and their values; in particular, cryotherapy or laser therapy in localised manifestations are mostly -favoured because of the convincing evidence from available data. In the case of a more disseminated haemangioma manifestation, the initiation of propranol medication is possible, a novel drug for this indication. However, there are no follow-up data on the mid-term or long-term outcome available at this time. Further studies on the subject are therefore required.

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2008

Lymphatic Research and Biology

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Basal Cell Carcinoma Arising 57 Years after Interstitial Radiotherapy of a Nasal Hemangioma

Cited by 3 publications

References 21 publications

Basal cell carcinoma arising at the site of a previously irradiated infantile hemangioma

Basal cell carcinoma arising at the site of a previously irradiated infantile hemangioma

Überblick der Therapiemöglichkeiten im Management von Säuglingshämangiomen

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