Bartholin gland cancer

Donato, Violante Di; Casorelli, Assunta; Bardhi, Erlisa; Vena, Flaminia; Marchetti, Cláudia; Muzii, Ludovico; Panici, Pierluigi Benedetti

doi:10.1016/j.critrevonc.2017.06.005

Cited by 48 publications

(69 citation statements)

References 96 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Diagnosis of BGC is established based upon histological examination. Abundant apoptotic debris and mitotic figures may be seen in SCNC of BG, and immunohistochemical stains were strongly positive for CAM 5.2, NSE, SYN, CHG, CD56 and CD10 ( 7 , 15 – 17 ). In the present case report, immunohistochemical stains obtained by the Shanghai Fengai Hospital were strongly positive for CAM 5.2 and CD20 and demonstrated an ACC that arose in BG.…”

Section: Discussionmentioning

confidence: 99%

“…BGC is a rare malignancy and accounts for fewer than 5% of all vulvar carcinomas ( 7 ). SCNC arising in BG is extremely rare, and only 3 cases have been reported in English literature ( 3 ).…”

Section: Discussionmentioning

confidence: 99%

“…In cases where BGC is suspected, the clinical diagnostic criteria is as follows: The tumor must be primarily located in the BG area; the surrounding skin must be undamaged; areas of apparent transition from normal to neoplastic elements must be observed; the histological tumor type must be consistent with the BG origin; there must be no evidence of a previous or subsequent primary tumor of similar histologic type elsewhere ( 12 , 13 ). Di Donato et al ( 7 ) collected all published manuscripts regarding BGC and the median age of patients was 52.99±13.94 years. Therefore, independent of whether a patient is pre- or post-menopausal, every mass within the BG area should be considered as a potential carcinoma until proven to be benign with biopsies of adequate size and depth ( 4 , 14 ).…”

Section: Discussionmentioning

confidence: 99%

“…Adenocarcinoma (ACC) and squamous cell carcinoma (SCC) are the predominating types of carcinoma at this site, occurring alongside ~80% of cases of BGC (equal frequency between ACC and SCC) ( 4 ). Di Donato et al (2017) conducted a literature search for all manuscripts discussing BGC, and identified only 3 reported cases of small cell neuroendocrine carcinoma (SCNC) in the Bartholin's gland (BG) ( 5 – 7 ). SCNC progresses aggressively, producing early local recurrences and distant metastases, resulting in eventual patient mortality.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Primary small cell neuroendocrine carcinoma of the Bartholin's gland: A case report

Wang

et al. 2018

Oncol Lett

View full text Add to dashboard Cite

Primary carcinoma of the Bartholin's gland (BG) is a rare malignancy. There are extremely rare cases of small cell neuroendocrine carcinoma (SCNC) of the BG reported in the English literature. A postmenopausal female presented with a 1-month history of increasing pain and swelling on the left vulva consistent with spontaneously bleeding. Pathology identified SCNC that arose in BG. The patient was treated with a radical wide local excision and bilateral inguinal lymph node dissection followed by six courses of chemotherapy. One month after primary treatment, without any pelvic recurrence or abnormal tumor markers indications, distant metastasis of the liver was diagnosed and VI hepatic lobectomy was performed. The patient maintained regular adjuvant chemotherapy every month under outpatient surveillance and has no local recurrence or distant metastasis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary small cell neuroendocrine carcinoma of the Bartholin's gland: A case report

Wang

et al. 2018

Oncol Lett

View full text Add to dashboard Cite

show abstract

“…Adenoid cystic carcinoma of the Bartholin's gland shares classic histologic features with adenoid cystic carcinoma of the salivary gland. It may originate from myoepithelial cells and histology is described as cells in cribriform patterns with mucin filled pseudo-lumens ( Di Donato et al, 2017 ). Most tumors have perineural invasion, which is thought to contribute to its high local recurrence rate.…”

Section: Discussionmentioning

confidence: 99%