Barriers to Implementation of Optimal Laboratory Biosafety Practices in Pakistan

Shakoor, Sadia; Shafaq, Humaira; Hasan, Rumina; Qureshi, Shahida; Dojki, Maqboola; Hughes, Molly A.; Zaidi, Anita K. M.; Khan, Erum

doi:10.1089/hs.2016.0031

Cited by 10 publications

(9 citation statements)

References 5 publications

(4 reference statements)

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“…The NUITM-KEMRI BSL-3 biosafety training program was initiated in 2007 following installation of the BSL-3 laboratory [ 3 , 4 ] and has been implemented annually to date. It equips BSL-3 laboratory workers and potential users with comprehensive biosafety and biosecurity knowledge and skills, towards ensuring compliance with safe practices that still remains low in most biomedical laboratories [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model

Muriithi

Bundi²,

Galata

et al. 2018

Trop Med Health

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The NUITM-KEMRI biosafety training program was developed for capacity building of new biosafety level three (BSL-3) laboratory users. The training program comprehensively covers biosafety and biosecurity theory and practice. Its training curriculum is based on the WHO biosafety guidelines, local biosafety standards, and ongoing biosafety level three research activities in the facility, also taking into consideration the emerging public health issues. The program’s training approach enhances the participant’s biosafety and biosecurity knowledge and builds their skills through the hands-on practice sessions and mentorship training. Subsequently, the trainees are able to integrate acquired knowledge and good practices into their routine laboratory procedures. This article describes implementation of the NUITM-KEMRI biosafety training program.

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Section: Introductionmentioning

confidence: 99%

Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model

Muriithi

Bundi²,

Galata

et al. 2018

Trop Med Health

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“…In fact, while there were no data in Pakistan on LAI, a survey conducted revealed six cases of individuals with known LIAs [13]. Contrary to the observations made in Pakistan with a lack of recognition for employees' rights and benefits in the workplace for biosafety, the LADISERO managers and workers are aware of the importance of biosafety as their rights [8]. Despite the insufficient working conditions, they are handling dangerous pathogens such as Bacillus anthracis, AIV, and RVFV.…”

Section: Biosafety and Biosecuritymentioning

confidence: 89%

“…This might apply to potentially dangerous micro-organisms as well by means of mutation; likewise, seemingly innocuous biological organisms may traverse species and cause disasters. For this purpose, biosafety and biosecurity are increasingly recognized globally as essential concerns for biomedical laboratories, whether the scope of work is clinical, educational, or research-based [8]. To improve the biorisk management, various partners (regional and national) are committed to providing countries with technical and financial supports.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Biosafety and Biosecurity in the Reference Veterinary Laboratory of Parakou in Benin

et al. 2021

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Optimal biosafety and biosecurity are major requirements of global health security. This study assessed the biorisk management in the reference veterinary laboratory of Parakou (Benin). The study was cross-sectional, descriptive, and evaluative. The non-probability sampling method with the reasoned choice was used. The Food and Agriculture Organization laboratory mapping tool-safety was used to collect information from the laboratory team. Group discussion, working environment observation, and document exploitation were the data collection techniques. The biorisk management was rated good if the average indicator of the laboratory reached at least 80%. Otherwise, the biorisk management was rated insufficient. The overall laboratory biosafety and biosecurity score was insufficient (42.4%). Per area, the scores were 26.7% for engineering, 33.3% for administration, 53.8% for personal protective equipment, and 62.3% for the operational. There was no area or category score that reached 80%. Containment, waste disposal, and personal protective equipment disposal were the best performing categories with a score above 60%. The laboratory has no biosafety and accident prevention program. Its premises require renovation. The standard operating procedures for biosafety are not yet finalized, and the training mechanism is not optimal. Therefore, strong advocacy and implementation of a biorisk management improvement plan appear as urgent corrective actions which are required to help the reference veterinary laboratory of Parakou in its task to protect the livestock and, ultimately, the people of Benin from dangerous diseases and emerging pathogens.

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“…In a study among Ugandan cattle farmers on perceived strategies to improve biosecurity, participants mentioned that absence of support from government, non-governmental organizations (NGOs) and other partners affected their adequate practice of biosecurity [ 21 ]. Another study conducted among workshop attendees on biosafety and biosecurity in Pakistan also revealed nonexistence of national regulatory control [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…Financial challenges have also been identified as barriers to establishing a biosafety level 3 (BSL-3) lab in low-income countries [ 24 ]. In Pakistan, increased cost of biosafety regulation execution were identified as a barrier in biosafety and biosecurity implementation [ 22 ]. This calls for government and other stakeholder commitments in terms of financial support in order to achieve successful implementation of biosafety and biosecurity.…”

Section: Discussionmentioning

confidence: 99%

Reasons for and barriers to biosafety and biosecurity training in health-related organizations in Africa, Middle East and Central Asia: findings from GIBACHT training needs assessments 2018-2019

Rutebemberwa¹,

Aku²,

Zein³

et al. 2020

Pan Afr Med J

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Introduction the Global-Partnership-Initiated-Biosecurity-Academia for Controlling Health Threats (GIBACHT) consortium conducts a biosafety and biosecurity training for fellows from Africa, the Middle East and Asia. To achieve a multiplier effect, fellows conduct trainings in their own organizations. It was during such trainings that training needs assessments were done assessing reasons for and barriers to biosafety and biosecurity training. Methods this was a cross sectional assessment. Trainings were conducted from April to July 2018 and April to June 2019. In 2018, training needs were explored using a structured tool. Responses were coded using manifest content analysis and key issues identified. In 2019, respondents quantified the identified key issues using a Likert scale. Proportions of those who strongly agreed, agreed, neither agreed nor disagreed, disagreed or strongly disagreed were calculated and results presented in tables and charts. Results in 2018 and 2019, there were 183 and 191 respondents respectively. About 96% of respondents in 2018 supported training in biosafety and biosecurity citing individual, community and global benefits. Barriers highlighted included governance, financial, human resource, information and infrastructure challenges. In 2019, majority of respondents indicated inadequate guidelines dissemination, lack of financial resources, inadequate personnel, lack of equipped laboratories and lack of instructional materials among major barriers. Conclusion support for biosafety and biosecurity training was high though systemic barriers exist. Improving human resource capacity and provision of instructional materials can be achieved through training programs. However, systemic assessments need to be done before each training as different organizations have different barriers.

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Barriers to Implementation of Optimal Laboratory Biosafety Practices in Pakistan

Cited by 10 publications

References 5 publications

Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model

Biosafety and biosecurity capacity building: insights from implementation of the NUITM-KEMRI biosafety training model

Assessment of the Biosafety and Biosecurity in the Reference Veterinary Laboratory of Parakou in Benin

Reasons for and barriers to biosafety and biosecurity training in health-related organizations in Africa, Middle East and Central Asia: findings from GIBACHT training needs assessments 2018-2019

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