Abstract:Research laboratories in low- and middle-income countries, where the global burden of disease is highest, face systemic challenges in conducting research and public health surveillance. An international effort is needed to overcome the paywalls, customs regulations and lack of local suppliers that hinder the scientific community in these countries.
“…the first has more immediate, albeit non-trivial solutions (e.g., by expanding the language pool of the researchers and studies included 16,97 and by applying common standards for sampling, extraction, and molecular protocols [98][99][100][101] ), the latter contains systemic issues that go beyond soil ecology alone. In this context, although the CBD and the Nagoya Protocol were created to protect countries while making the transfer of biological material more agile, numerous states have either not yet implemented effective national "Access and Benefit Sharing" (ABS) laws or have implemented very strict regulations 102,103 . Yet, even after 25 years of the CBD and the ABS framework being in place, the major motivation for a strict national regulation -the anticipated commercial benefits and high royalties from the "green gold"has not yet materialized 95,104 .…”
Soils harbor a substantial fraction of the world's biodiversity, contributing to many crucial ecosystem functions. It is thus essential to identify general macroecological patterns related to the distribution and functioning of soil organisms to support their conservation and consideration by governance. These macroecological analyses need to represent the diversity of environmental conditions that can be found worldwide. Here we identify and characterize existing environmental gaps in soil taxa and ecosystem functioning data across soil macroecological studies and 17,186 sampling sites across the globe. These data gaps include important spatial, environmental, taxonomic, and functional gaps, and an almost complete absence of temporally explicit data. We also identify the limitations of soil macroecological studies to explore general patterns in soil biodiversity-ecosystem functioning relationships, with only 0.3% of all sampling sites having both information about biodiversity and function, although with different taxonomic groups and functions at each site. Based on this information, we provide clear priorities to support and expand soil macroecological research.
“…the first has more immediate, albeit non-trivial solutions (e.g., by expanding the language pool of the researchers and studies included 16,97 and by applying common standards for sampling, extraction, and molecular protocols [98][99][100][101] ), the latter contains systemic issues that go beyond soil ecology alone. In this context, although the CBD and the Nagoya Protocol were created to protect countries while making the transfer of biological material more agile, numerous states have either not yet implemented effective national "Access and Benefit Sharing" (ABS) laws or have implemented very strict regulations 102,103 . Yet, even after 25 years of the CBD and the ABS framework being in place, the major motivation for a strict national regulation -the anticipated commercial benefits and high royalties from the "green gold"has not yet materialized 95,104 .…”
Soils harbor a substantial fraction of the world's biodiversity, contributing to many crucial ecosystem functions. It is thus essential to identify general macroecological patterns related to the distribution and functioning of soil organisms to support their conservation and consideration by governance. These macroecological analyses need to represent the diversity of environmental conditions that can be found worldwide. Here we identify and characterize existing environmental gaps in soil taxa and ecosystem functioning data across soil macroecological studies and 17,186 sampling sites across the globe. These data gaps include important spatial, environmental, taxonomic, and functional gaps, and an almost complete absence of temporally explicit data. We also identify the limitations of soil macroecological studies to explore general patterns in soil biodiversity-ecosystem functioning relationships, with only 0.3% of all sampling sites having both information about biodiversity and function, although with different taxonomic groups and functions at each site. Based on this information, we provide clear priorities to support and expand soil macroecological research.
“…While the first has more immediate, albeit non-trivial solutions (e.g., by expanding the language pool of the researchers and studies included 16,95 and by applying common standards for sampling, extraction, and molecular protocols [96][97][98][99] ), the latter contains systemic issues that go beyond soil ecology alone. In this context, although the CBD and the Nagoya Protocol were created to protect countries while making the transfer of biological material more agile, numerous states have either not yet implemented effective national Access and Benefit Sharing (ABS) laws or have implemented very strict regulations 100,101 . Yet, even after 25 years of the CBD and the ABS framework being in place, the major motivation for a strict national regulationthe anticipated commercial benefits and high royalties from the "green gold" -has not yet materialized 93,102 .…”
Section: Challenges To Move Beyond Blind Spotsmentioning
Soils harbor a substantial fraction of the world's biodiversity, contributing to many crucial ecosystem functions. It is thus essential to identify general macroecological patterns related to the distribution and functioning of soil organisms to support their conservation and governance. Here we identify and characterize the existing gaps in soil biodiversity and ecosystem function data across soil macroecological studies and >11,000 sampling sites. These include significant spatial, environmental, taxonomic, and functional gaps, and an almost complete absence of temporally explicit data. We also identify the limitations of soil macroecological studies to explore general patterns in soil biodiversity-ecosystem functioning relationships, with only 0.6% of all sampling sites having a non-systematic coverage of both biodiversity and function datasets. Based on this information, we provide clear priorities to support and expand soil macroecological research.
“…31 In low and middle income countries (LMICs), surveillance is often further complicated by lack of access to laboratory equipment, service contracts and paywalled literature. 32 Ensuing disparities in global AMR reporting mean that international reports disproportionately reflect data from resource-rich settings and a limited number of well-studied low-income sentinel sites with international healthcare infrastructure investment. 33 Resulting international stewardship and policy guidelines may, however, be of limited use in understudied resource-poor settings with different AMR ecologies and no access to key antibiotics.…”
Section: Stagementioning
confidence: 99%
“…128 The described surveillance disconnect is exacerbated by the relative lack of data from LICs and rural settings (see Metrics above). The result is a vicious circle: lacking access to equipment, current standards and scholarly literature means that disease and AMR burdens cannot be measured and published, 32 which means that there are no data with which to build local expert capacity or inform international policy, which compounds the obscuring of difference between contexts.…”
There is increasing concern globally about the enormity of the threats posed by antimicrobial resistance (AMR) to human, animal, plant and environmental health. A proliferation of international, national and institutional reports on the problems posed by AMR and the need for antibiotic stewardship have galvanised attention on the global stage. However, the AMR community increasingly laments a lack of action, often identified as an ‘implementation gap’. At a policy level, the design of internationally salient solutions that are able to address AMR’s interconnected biological and social (historical, political, economic and cultural) dimensions is not straightforward. This multidisciplinary paper responds by asking two basic questions: (A) Is a universal approach to AMR policy and antibiotic stewardship possible? (B) If yes, what hallmarks characterise ‘good’ antibiotic policy? Our multistage analysis revealed four central challenges facing current international antibiotic policy: metrics, prioritisation, implementation and inequality. In response to this diagnosis, we propose three hallmarks that can support robust international antibiotic policy. Emerging hallmarks for good antibiotic policies are: Structural, Equitable and Tracked. We describe these hallmarks and propose their consideration should aid the design and evaluation of international antibiotic policies with maximal benefit at both local and international scales.
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