Barrett's esophagus and esophageal adenocarcinoma: the scope of the problem

Gastro-oesophageal reflux demonstrated by radiography. . A supplement to 24-h pH monitoring

“…However, the male predominance of patients with Barrett’s oesophagus (23) was not observed in this study. Nor was the classical radiological features of Barrett’s oesophagus with stricture formation and a hiatal hernia (19) found in this study. Rings and strictures were seen both with and without concomitant Barrett’s oesophagus.…”

Gastrointestinal Case of the Day

“…Low-grade dysplasia may develop into high-grade dysplasia and intramucosal adenocarcinoma (7). High-grade dysplasia progresses into carcinoma in 15%-20% of patients (3). Indicators of neoplasia include biomarkers (ornithine decarboxylase, carcinoembryonic antigen, mucus abnormalities), chromosomal abnormalities (tumor suppressor genes, oncogenes), flow cytometry (aneuploidy, cellular proliferation), and growth regulatory factors.…”

Endoscopic Fluorescence Detection of Intraepithelial Neoplasia in Barrett's Esophagus after Oral Administration of Aminolevulinic Acid

“…Nevertheless, endoscopic evaluation combined with biopsies remains a procedure that investigates only a small portion of the epithelial surface at risk. New diagnostic procedures, such as cytological sampling by balloons and brushes [12], endosonography [13], radiological procedures, [14] or in vivo dye staining of the Barrett's mucosa [15] have been evaluated. Unfortunately, these procedures have failed to increase the diagnostic ability for detecting dysplastic lesions or early adenocarcinomas in Barrett's esophagus.…”