2010
DOI: 10.1590/s0365-05962010000200009
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Barreira cutânea na dermatite atópica

Abstract: Research about the skin barrier and its properties has increased significantly since the 60s, with studies that indicated its resistance when isolated, as well as its particularities in relation to skin permeability. At the same time, description of Odland bodies helped to understand how stratum corneum stability is maintained. The "brick and mortar" model is the most accepted so far. In this analogy, the corneocytes are the bricks and the intercellular lipids are the mortar. Currently, there is concrete evide… Show more

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Cited by 38 publications
(25 citation statements)
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References 67 publications
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“…New concepts have emerged, demonstrating immunological and inflammatory dysfunctions, besides the importance of environmental factors. 4,17,18 …”
Section: Etiopathogenesismentioning
confidence: 99%
“…New concepts have emerged, demonstrating immunological and inflammatory dysfunctions, besides the importance of environmental factors. 4,17,18 …”
Section: Etiopathogenesismentioning
confidence: 99%
“…22 A hidratação é importante para prevenir e controlar a DA, pois o paciente atópico apresenta barreira cutânea deficiente e pele sensível. 23 Os objetivos são restaurar essa barreira e evitar a perda de água transepidérmica. 23 Recomenda-se evitar banhos demorados e quentes, buchas de banho, piscinas cloradas e ar condicionado.…”
Section: Tratamentounclassified
“…23 Os objetivos são restaurar essa barreira e evitar a perda de água transepidérmica. 23 Recomenda-se evitar banhos demorados e quentes, buchas de banho, piscinas cloradas e ar condicionado. Os pacientes devem ser orientados a utilizar sabonetes neutros e emolientes após o banho.…”
Section: Tratamentounclassified
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“…Iniciase geralmente na infância, nos primeiros anos de vida e há uma tendência de involução no decorrer dos anos, persistindo em apenas 20% dos pacientes após a adolescência (Costa & Nogueira, 2010;Addor & Aoki, 2010). Geralmente está associada a outras doenças atópicas como a rinite alérgica e a asma (Cestari, 2010).…”
Section: Introductionunclassified