“…In recent years, new findings on disease-related immunological factors have fundamentally changed the treatment of psoriasis and introduced new drugs (Mrowietz et al, 2011). There is a case-controlled study in the international literature showing that Kangal hot spring is effective in the treatment of psoriasis patients, while there are various studies and anecdotal observations in the national literature reporting that it is effective in skin diseases, especially psoriasis (Sayili et al, 2007;Uysal et al, 2019;Özçelik et al, 2000;Grassberger and Hoch, 2006;Özçelik and Hayta, 2015;Duman and Şahan, 2017;Karaaslan et al, 2010a;Karaaslan et al, 2010b). With all this information, thermomineral waters that do not belong to any special water group are classified as mixed waters and the most common ones in these waters are chloride (Cl -), sulfate (SO4 -), bicarbonate (HCO3 -) anions and sodium (Na + ), calcium (Ca +2 ) and magnesium (Mg +2 ) cations.…”