Balneotherapy for atopic dermatitis in children at Comano spa in Trentino, Italy

Farina, Stefania; Gisondi, Paolo; Zanoni, Mauro; Pace, Maria Caterina; Rizzoli, Laura; Baldo, Ermanno; Girolomoni, Giampiero

doi:10.3109/09546634.2010.512950

Cited by 38 publications

(37 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Conventional balneotherapy with or without synchronous UV therapy has been shown to be effective in AE but was not considered as CAM in this chapter. Balneotherapy with thermal spring water has been shown to be beneficial in children with mild to moderate AE with an effect similar to mid‐potency topical corticosteroids …”

Section: Complementary and Alternative Medicine In Atopic Eczemamentioning

confidence: 99%

Consensus‐based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II

Wollenberg

Barbarot

Bieber

et al. 2018

Acad Dermatol Venereol

580

717

View full text Add to dashboard Cite

This guideline was developed as a joint interdisciplinary European project, including physicians from all relevant disciplines as well as patients. It is a consensus-based guideline, taking available evidence from other guidelines, systematic reviews and published studies into account. This second part of the guideline covers antimicrobial therapy, systemic treatment, allergen-specific immunotherapy, complementary medicine, psychosomatic counselling and educational interventions, whereas the first part covers methods, patient perspective, general measures and avoidance strategies, basic emollient treatment and bathing, dietary intervention, topical anti-inflammatory therapy, phototherapy and antipruritic therapy. Management of AE must consider the individual clinical variability of the disease. Systemic immunosuppressive treatment with cyclosporine, methotrexate, azathioprine and mycophenolic acid is established option for severe refractory cases, and widely available. Biologicals targeting the T helper 2 pathway such as dupilumab may be a safe and effective, disease-modifying alternative

show abstract

Section: Complementary and Alternative Medicine In Atopic Eczemamentioning

confidence: 99%

Consensus‐based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II

Wollenberg

Barbarot

Bieber

et al. 2018

Acad Dermatol Venereol

580

717

View full text Add to dashboard Cite

show abstract

“…This unblinded trial 439 compared Comano spa water (Trentino, Italy) balneotherapy against topical corticosteroid treatment for 2 weeks. It was not clear whether, or how often, the corticosteroid treatment group bathed.…”

Section: Studiesmentioning

confidence: 99%

Scoping systematic review of treatments for eczema

Nankervis

Kim

Delamere

et al. 2016

Programme Grants Appl Res

View full text Add to dashboard Cite

BackgroundEczema is a very common chronic inflammatory skin condition.ObjectivesTo update the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) systematic review of treatments for atopic eczema, published in 2000, and to inform health-care professionals, commissioners and patients about key treatment developments and research gaps.Data sourcesElectronic databases including MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Skin Group Specialised Register, Latin American and Caribbean Health Sciences Literature (LILACS), Allied and Complementary Medicine Database (AMED) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) were searched from the end of 2000 to 31 August 2013. Retrieved articles were used to identify further randomised controlled trials (RCTs).Review methodsStudies were filtered according to inclusion criteria and agreed by consensus in cases of uncertainty. Abstracts were excluded and non-English-language papers were screened by international colleagues and data were extracted. Only RCTs of treatments for eczema were included, as other forms of evidence are associated with higher risks of bias. Inclusion criteria for studies included availability of data relevant to the therapeutic management of eczema; mention of randomisation; comparison of two or more treatments; and prospective data collection. Participants of all ages were included. Eczema diagnosis was determined by a clinician or according to published diagnostic criteria. The risk of bias was assessed using the Cochrane Collaboration risk-of-bias tool. We used a standardised approach to summarising the data and the assessment of risk of bias and we made a clear distinction between what the studies found and our own interpretation of study findings.ResultsOf 7198 references screened, 287 new trials were identified spanning 92 treatments. Trial reporting was generally poor (randomisation method: 2% high, 36% low, 62% unclear risk of bias; allocation concealment: 3% high, 15% low, 82% unclear risk of bias; blinding of the intervention: 15% high, 28% low, 57% unclear risk of bias). Only 22 (8%) trials were considered to be at low risk of bias for all three criteria. There was reasonable evidence of benefit for the topical medications tacrolimus, pimecrolimus and various corticosteroids (with tacrolimus superior to pimecrolimus and corticosteroids) for both treatment and flare prevention; oral ciclosporin; oral azathioprine; narrow band ultraviolet B (UVB) light; Atopiclair™ and education. There was reasonable evidence to suggest no clinically useful benefit for twice-daily compared with once-daily topical corticosteroids; corticosteroids containing antibiotics for non-infected eczema; probiotics; evening primrose and borage oil; ion-exchange water softeners; protease inhibitor SRD441 (Serentis Ltd); furfuryl palmitate in emollient; cipamfylline cream; andMycobacterium vaccaevaccine. Additional research evidence is needed for emollients, bath additives, antibacterials, specialist clothing and complementary and alternative therapies. There was no RCT evidence for topical corticosteroid dilution, impregnated bandages, soap avoidance, bathing frequency or allergy testing.LimitationsThe large scope of the review coupled with the heterogeneity of outcomes precluded formal meta-analyses. Our conclusions are still limited by a profusion of small, poorly reported studies.ConclusionsAlthough the evidence base of RCTs has increased considerably since the last NIHR HTA systematic review, the field is still severely hampered by poor design and reporting problems including failure to register trials and declare primary outcomes, small sample size, short follow-up duration and poor reporting of risk of bias. Key areas for further research identified by the review include the optimum use of emollients, bathing frequency, wash products, allergy testing and antiseptic treatments. Perhaps the greatest benefit identified is the use of twice weekly anti-inflammatory treatment to maintain disease remission. More studies need to be conducted in a primary care setting where most people with eczema are seen in the UK. Future studies need to use the same core set of outcomes that capture patient symptoms, clinical signs, quality of life and the chronic nature of the disease.FundingThe National Institute for Health Research Programme Grants for Applied Research programme.

show abstract

“…Patients with atopic dermatitis, psoriasis (Casas et al 2011;Costantino 2008a;Costantino and Lampa 2005;Delfino et al 2003;Farina et al 2011;Merial-Kieny et al 2011;Taieb et al 2011;Tsoureli-Nikita et al 2002) or inherited ichthyosis (Bodemer et al 2011) received balneotherapy including baths, showers, spray baths, underwater massages, drinking cures and mud therapy. In the studies, significant short-and longterm improvements in clinical outcomes such as severity of disease and qol were achieved.…”

Section: Skin Diseasesmentioning

confidence: 99%

“…In Germany, it would be therefore termed "balneotherapy" (Gutenbrunner et al 2010) the treatment of mild CHF (Michalsen et al 2003) and hypertension (Jacob and Volger 2009); (4) balneotherapy in the treatment of atopic dermatitis (Farina et al 2011), psoriasis (mud therapy) (Costantino 2008a;Costantino and Lampa 2005;Delfino et al 2003), chronic venous insufficiency (Carpentier and Satger 2009), symptomatic varicosis (Mancini et al 2003), overweight/obesity (Hanh et al 2012), chronic inflammatory gynaecological disorders (Zambo et al 2008) and generalized anxiety disorder ( Dubois et al 2010); (5) aquatic exercise in the treatment of CHF (Cider et al 2003); and (6) spa therapy in the treatment of Parkinson's disease (Brefel-Courbon et al 2003). Most of the 22 uncontrolled studies report significant within-group improvements over time.…”

Section: Respiratory Diseasesmentioning

confidence: 99%

Health resort medicine in non-musculoskeletal disorders: is there evidence of its effectiveness?

et al. 2015

View full text Add to dashboard Cite

Health resort medicine (HRM; in German: Kurortmedizin) is a field of medicine with long-lasting tradition in several European countries. A number of systematic reviews have shown the effectiveness of HRM in musculoskeletal conditions. Reviews focusing on the effectiveness of HRM in non-musculoskeletal disorders are rare. This systematic review aims to provide an overview about all types of health resort treatments applied in non-musculoskeletal conditions, to summarize evidence for its effectiveness and to assess the quality of published studies. MEDLINE, Web of Knowledge and Embase were searched for articles published between January 2002 and December 2013. We used a broad search strategy in order to find studies investigating the effects of HRM in non-musculoskeletal disorders. Two authors independently extracted data and assessed quality using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies (EPHPP-QAT). Forty-one studies (19 of them with control group) from eight countries examining the efficacy of various forms of spa treatment for 12 disease groups were included. The studies are markedly heterogeneous regarding study design, population and treatment. HRM treatment is associated with clinical improvement in diseases of the skin, respiratory, circulatory, digestive and nervous system among others. However, small samples, the lack of control groups and an insufficient follow-up often limit the generated evidence. The scientific literature of the last decade has shown that a number of non-musculoskeletal disorders are treated with different kinds of HRM. The challenge for the future will be to carry out thoroughly designed studies in larger patient populations to corroborate the impact of HRM treatment on non-musculoskeletal disorders.

show abstract

Balneotherapy for atopic dermatitis in children at Comano spa in Trentino, Italy

Abstract: Balneotherapy at Comano spa appears to be beneficial in children with mild to moderate AD.

Cited by 38 publications

References 25 publications

Consensus‐based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II

Consensus‐based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part II

Scoping systematic review of treatments for eczema

Health resort medicine in non-musculoskeletal disorders: is there evidence of its effectiveness?

Contact Info

Product

Resources

About