Bakteriális infekciók májátültetés után

Nemes, Balázs; Gelley, Fanni; Dabasi, Eszter; Gámán, György; Fehérvári, Imre; Görög, Dénes; Kopper, László; Fazakas, János; Vitális, Eszter; Doros, Attila; Gálffy, Zsuzsanna; Máthé, Z.

doi:10.1556/650.2015.30204

Cited by 6 publications

(4 citation statements)

References 56 publications

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“…The hepatitis E virus issue seems to be more critical since health care personnel usually are less vigilant with this virus in general and its transmission by transfusion procedures. It became apparent during the last couple of years that E virus-induced hepatitis is pretty common in the U.K. and other European countries, and as a consequence, this virus can be transmitted with the transfusion or blood components outside of endemic areas [ 46 , 48 , 49 ]. Therefore, it is essential to screen the donors and, in the meanwhile, further identify screening methods for hepatitis virus safety.…”

Section: Viral Transmissionmentioning

confidence: 99%

“…Therefore, direct E virus PCR would be desired to provide reliable data on transfusion safety. This PCR is still not easily and readily available, but proteinuria, chronic liver disease markers, splenomegaly, and blood count abnormalities (hemolysis, cytopenia) might also call attention to E virus persistence [ 44 , 45 , 46 , 48 ]. The success of the recent introduction of mandatory HEV NAT testing in 2020 have to be summarized in the upcoming years.…”

Section: Viral Transmissionmentioning

confidence: 99%

“…The administration of allogenic grafts to the recipients confers the risk of infectious and non-infectious disease transmission [ 48 , 98 , 99 , 108 ]. This risk can be minimized by thorough donor testing.…”

Section: Areas Of Particular Interestmentioning

confidence: 99%

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Transfusion-Transmitted Disorders 2023 with Special Attention to Bone Marrow Transplant Patients

et al. 2023

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Transfusion medicine is traditionally a strong/fundamental part of clinical practice, saving hundreds of millions of lives. However, blood-borne or transmitted infections are a well-known and feared possibility, a risk we relentlessly mitigate. Pathogens are continuously and rather quickly changing, so during the last decade, many, sometimes exotic, new pathogens and diseases were recorded and analyzed, and some of them were proved to be transmitted with transfusions. Blood or blood component transfusions are carried out after cautious preparative screening and inactivation maneuvers, but in some instances, newly recognized agents might escape from standard screening and inactivation procedures. Here, we try to focus on some of these proven or potentially pathogenic transfusion-transmitted agents, especially in immunocompromised patients or bone marrow transplantation settings. These pathogens are sometimes new challenges for preparative procedures, and there is a need for more recent, occasionally advanced, screening and inactivation methods to recognize and eliminate the threat a new or well-known pathogen can pose. Pathogen transmission is probably even more critical in hemophiliacs or bone marrow transplant recipients, who receive plasma-derived factor preparations or blood component transfusions regularly and in large quantities, sometimes in severely immunosuppressed conditions. Moreover, it may not be emphasized enough that transfusions and plasma-derived product administrations are essential to medical care. Therefore, blood-borne transmission needs continued alertness and efforts to attain optimal benefits with minimized hazards.

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Section: Viral Transmissionmentioning

confidence: 99%

Section: Viral Transmissionmentioning

confidence: 99%

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Transfusion-Transmitted Disorders 2023 with Special Attention to Bone Marrow Transplant Patients

et al. 2023

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“…Netherlands: interestingly coagulase-negative staphylococci is the most common.Yershinia Enterocolitica can tolerate lower temperatures quite well, so may be persistent even after longer storage periods [5][6][7][8][9]. Bacterial transmission can be important issue in interventions with unusually large transfusion need (liver transplantation, etc) so it should receive special care and attention [10].…”

Section: New Infectious Agent Data and New Approach To Transfusion Tr...mentioning

confidence: 99%

Newly Recognised or New Blood Transfusion Transmitted Infections. Challenges, to be Faced by Clinicians, Transfusion Experts, Which Certainly Needs Refreshed Blood Banking Skills and Clinical Approaches

Udvardy¹

2018

BJSTR

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Preparative and clinical transfusiology and transfusion, a majestic part of clinical medicine saved and saves the life of hundred millions. However, times and pathogens are continously and rather quickly changig, so during the last decade many not only egzotic new or newly recognised pathogens and diseases were showed up, and some of them (e.g. Zyka virus, Hepatitis E vrus, Ebola, etc.) can also be transmitted by blood or blood component transfusions, and in some instances they escape from standard screening and inactivation procedures. Hereby we try to focus and draw attention to some of these potentially pathogen new bloodborne microbiological agents, and along with this we try to emphasize the significance of application of updated next generation screenig and inactivation procedures. Interestingly a recent British trial, based on large population data showed some evidence of slight increase of non Hodgkin lymphoma incidence in patients with multiple previous transfusions.Our approach is purely a clinician one (clinical hematologist), bedside oriented. These new facts, knowledge and skills are badly needed for all of us: doctors (a broad, almost entire range of specialists), blood banking people, departments of epidemiology and also some special cohorts of patients: i.e. for the hemophiliacs and their family, who still receive plasma derived prophylactic treatment 3 times weekly. It is due time, that some especially endangered cohorts of patients and family should receive the necessary information, and go for a fully informed consent based preference, based on the advantages and hazards of particular treatment modalities.

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New Challenges in the Hungarian Organ Transplant Programs

Máthé

2016

Transplantation Proceedings

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Bakteriális infekciók májátültetés után

Cited by 6 publications

References 56 publications

Transfusion-Transmitted Disorders 2023 with Special Attention to Bone Marrow Transplant Patients

Transfusion-Transmitted Disorders 2023 with Special Attention to Bone Marrow Transplant Patients

Newly Recognised or New Blood Transfusion Transmitted Infections. Challenges, to be Faced by Clinicians, Transfusion Experts, Which Certainly Needs Refreshed Blood Banking Skills and Clinical Approaches

New Challenges in the Hungarian Organ Transplant Programs

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