Baker's yeast reduction of α-haloacetophenones

Carvalho, Marcia; Okamoto, M.; Moran, Paulo J. S.; Rodrigues, J. Augusto R.

doi:10.1016/s0040-4020(01)96117-4

Cited by 48 publications

(14 citation statements)

References 28 publications

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“…Bioreduction by Rhodotorula sp. obeyed Prelog's rule, showing the same enantiomeric preference already observed with baker's yeast (S. cerevisiae) (de Carvalho et al, 1991).…”

Section: Reduction Of Acetophenone (1)supporting

confidence: 75%

Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Silva

Alarcón

Águila

et al. 2010

Zeitschrift Für Naturforschung C

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Bioreduction of several prochiral carbonylic compounds such as acetophenone (1), ethyl acetoacetate (2) and ethyl phenylpropionate (3) to the corresponding optically active secalcohols 1a -3a was performed using wild-type strains of Pichia pastoris UBB 1500, Rhodotorula sp., and Saccharomyces cerevisiae. The reductions showed moderate to excellent conversion and high enantiomeric excess, in an extremely mild and environmentally benign manner in aqueous medium, using glucose as cofactor regeneration system. The obtained alcohols follow Prelog's rule, but in the reduction of 1 with P. pastoris UBB 1500 the antiPrelog enantiopreference was observed.

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“…Bioreduction by Rhodotorula sp. obeyed Prelog's rule, showing the same enantiomeric preference already observed with baker's yeast (S. cerevisiae) (de Carvalho et al, 1991).…”

Section: Reduction Of Acetophenone (1)supporting

confidence: 75%

Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Silva

Alarcón

Águila

et al. 2010

Zeitschrift Für Naturforschung C

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“…Its persistence can be attributed to local inflammatory reaction and to the quantity of material used in trauma repair (Table 3). It is important to consider that polyglactin 910 is a thread with short exudative phase, early proliferative phase and absorption by minimal tissue reaction (17) .…”

Section: Discussionmentioning

confidence: 99%

Randomized controlled clinical trial on two perineal trauma suture techniques in normal delivery

Almeida¹,

Riesco

2008

Rev. Latino-Am. Enfermagem

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“…They obtained the azidoalcohols, the corresponding optically active products, with good yields and enantiomeric excess (Moran et al 1994). Other works used Baker's yeast immobilized on chrysotile for the reduction of phenylketones , α-haloacetophenones (Carvalho et al 1991, Aleixo et al 1993, and the enantioselective synthesis of (R)-(-)-1-phenylethanolamines (Brenelli et al 1992). Lipase from Candida cylindracea was also immobilized on chrysotile and used successfully in organic synthesis (Lima et al 1996).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the catalytic activity of lipases immobilized on chrysotile for esterification

Silva

Jesus

2003

An. Acad. Bras. Ciênc.

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In the present work, the ester synthesis in organic media catalyzed by lipases immobilized on chrysotile was studied. Lipases of different sources (Mucor javanicus, Pseudomonas cepacia, Rhizopus oryzae, Aspergillus niger and Candida rugosa) were immobilized on chrysotile, an inexpensive magnesium silicate, and used for esterification of hexanoic, octanoic and lauric acid with methanol, ethanol, 1-butanol and 1-octanol at 25 • C in hexane as solvent. The best results were obtained with Mucor javanicus lipase and lauric acid giving yields of 62-97% of ester.

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Baker's yeast reduction of α-haloacetophenones

Cited by 48 publications

References 28 publications

Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Bioreduction of Some Common Carbonylic Compounds Mediated by Yeasts

Randomized controlled clinical trial on two perineal trauma suture techniques in normal delivery

Evaluation of the catalytic activity of lipases immobilized on chrysotile for esterification

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