Bacteriophage Therapy of Staphylococcic Septic Obstruction of the Cavernous Sinus

Indications and Limitations of Phage Therapy in Human Medicine: Personal Experience and Literature Review

“…André Raiga, like Ward J. MacNeal already mentioned, had reported in the early 1930s cases of sepsis cured by adapted phage therapy [134,135]. These same authors [136] also presented cases of thrombosis of the cavernous sinus, particularly dangerous in terms of prognosis. It is worth noting in 1978 the treatment of Serratia endocarditis by bacteriophages [137] and recently a P. aeruginosa septicaemia in a 2-year-old child with a combination of two bacteriophages [138].…”

Indications and Limitations of Phage Therapy in Human Medicine: Personal Experience and Literature Review

“…André Raiga, like Ward J. MacNeal already mentioned, had reported in the early 1930s cases of sepsis cured by adapted phage therapy [134,135]. These same authors [136] also presented cases of thrombosis of the cavernous sinus, particularly dangerous in terms of prognosis. It is worth noting in 1978 the treatment of Serratia endocarditis by bacteriophages [137] and recently a P. aeruginosa septicaemia in a 2-year-old child with a combination of two bacteriophages [138].…”

Clinical Indications and Compassionate Use of Phage Therapy: Personal Experience and Literature Review with a Focus on Osteoarticular Infections

“…Inherently, phages are able to treat any clinical presentation of bacterial infections. Reports have been published using phage therapy for a large array of clinical indications, including gastro-intestinal [2,11,52,53,54], localized [3,37,55,56,57,58,59], burn wound [9,60], systemic [21,39,61,62,63,64,65,66,67,68,69,70,71,72], urogenital [10,73,74,75,76,77,78,79,80,81,82], respiratory [44,45,47,82,83,84,85], oto-rhino-laryngeal (ORL) [12,86,87,88,89,90,91,92,93,94,95], and osteoarticular infections (see section below). These clinical indications include infections that are acute or chronic, sensitive or resistant to antibiotics, and are caused by highly variable common or opportunistic pathogens.…”

Cavernous sinus thrombophlebitis: A review

“…Prior to the introduction of the sulphonamides it was well recognized that this infection was nearly always fatal. It is true that MacNeal, Frisbee, and Blevins (1943) were able to trace 50 instances of recovery before sulphonamides came …”

Indications and Limitations of Phage Therapy in Human Medicine: Personal Experience and Literature Review

“…André Raiga, like Ward J. MacNeal already mentioned, had reported in the early 1930s cases of sepsis cured by adapted phage therapy [134,135]. These same authors [136] also presented cases of thrombosis of the cavernous sinus, particularly dangerous in terms of prognosis. It is worth noting in 1978 the treatment of Serratia endocarditis by bacteriophages [137] and recently a P. aeruginosa septicaemia in a 2-year-old child with a combination of two bacteriophages [138].…”

Clinical Indications and Compassionate Use of Phage Therapy: Personal Experience and Literature Review with a Focus on Osteoarticular Infections

“…Inherently, phages are able to treat any clinical presentation of bacterial infections. Reports have been published using phage therapy for a large array of clinical indications, including gastro-intestinal [2,11,52,53,54], localized [3,37,55,56,57,58,59], burn wound [9,60], systemic [21,39,61,62,63,64,65,66,67,68,69,70,71,72], urogenital [10,73,74,75,76,77,78,79,80,81,82], respiratory [44,45,47,82,83,84,85], oto-rhino-laryngeal (ORL) [12,86,87,88,89,90,91,92,93,94,95], and osteoarticular infections (see section below). These clinical indications include infections that are acute or chronic, sensitive or resistant to antibiotics, and are caused by highly variable common or opportunistic pathogens.…”

Cavernous sinus thrombophlebitis: A review

“…Prior to the introduction of the sulphonamides it was well recognized that this infection was nearly always fatal. It is true that MacNeal, Frisbee, and Blevins (1943) were able to trace 50 instances of recovery before sulphonamides came …”

Indications and Limitations of Phage Therapy in Human Medicine: Personal Experience and Literature Review

“…André Raiga, like Ward J. MacNeal already mentioned, had reported in the early 1930s cases of sepsis cured by adapted phage therapy [134,135]. These same authors [136] also presented cases of thrombosis of the cavernous sinus, particularly dangerous in terms of prognosis. It is worth noting in 1978 the treatment of Serratia endocarditis by bacteriophages [137] and recently a P. aeruginosa septicaemia in a 2-year-old child with a combination of two bacteriophages [138].…”

Clinical Indications and Compassionate Use of Phage Therapy: Personal Experience and Literature Review with a Focus on Osteoarticular Infections

“…Inherently, phages are able to treat any clinical presentation of bacterial infections. Reports have been published using phage therapy for a large array of clinical indications, including gastro-intestinal [2,11,52,53,54], localized [3,37,55,56,57,58,59], burn wound [9,60], systemic [21,39,61,62,63,64,65,66,67,68,69,70,71,72], urogenital [10,73,74,75,76,77,78,79,80,81,82], respiratory [44,45,47,82,83,84,85], oto-rhino-laryngeal (ORL) [12,86,87,88,89,90,91,92,93,94,95], and osteoarticular infections (see section below). These clinical indications include infections that are acute or chronic, sensitive or resistant to antibiotics, and are caused by highly variable common or opportunistic pathogens.…”

Cavernous sinus thrombophlebitis: A review

“…Prior to the introduction of the sulphonamides it was well recognized that this infection was nearly always fatal. It is true that MacNeal, Frisbee, and Blevins (1943) were able to trace 50 instances of recovery before sulphonamides came …”