Bactericidal Properties of Copper-Tin Nanoparticles on Escherichia coli in a Liquid Environment

Abstract

In this research, copper-tin alloy nanoparticles were made by a mechanical alloying method and were examined by two well-known and common bactericidal tests, optical density, and colony-forming units count in terms of bactericidal properties. To confirm the results, two different percentages were used as Sn-50Cu and Sn-83Cu, and standard amounts of these alloys were added to the Escherichia coli bacterial culture medium. The results of optical density show that with the addition of more values to the culture medium for bacteria, witnessing the destruction of bacteria, and also the results of colony counting tests can be seen that the number of colonies has decreased over time, even close to zero, which means the environment is free of bacteria. These standard values were different for both alloys; for the Sn-50Cu alloy, the maximum value was 4.5 mg, and for the Sn-83Cu alloy, it was 2.75 mg, which did not make any difference with the addition of these nanoparticles to the bacterial culture medium.

Influence of Aluminum and Copper on Mechanical Properties of Biocompatible Ti-Mo Alloys: A Simulation-Based Investigation

“…The present investigation involved the addition of copper and aluminum elements to the alloy composition using JMatPro 7.0 developed by the British Thermotech company, Louth, UK, a software application for engineering materials analysis and design. The choice of copper was based on its favorable biocompatibility [ 40 ], while titanium was chosen due to its known biocompatible properties. On the other hand, aluminum was not used as it is associated with various biological problems.…”

Statistical analysis of experimental factors for synthesis of copper oxide and tin oxide for antibacterial applications

“…The use of graphite helped to prevent fine dust particles from clumping together and facilitated a higher quality milling operation. Alloys with varying proportions of both elements were produced based on previous research study [3], as detailed in Table 1. The amount of material used in the experiment was determined through the application of Equation (1) based on thermodynamic analysis and regenerative reaction.…”

“…Antibacterial copper and tin oxide nanoparticles have emerged as promising alternatives to traditional antibiotics due to their unique physicochemical properties and superior antibacterial activity [1], [2]. These nanoparticles can effectively inhibit bacterial growth and prevent the spread of antibiotic-resistant bacterial strains [3]- [5]. However, synthesizing these nanoparticles requires careful optimization of experimental factors to achieve desirable properties.…”

Characterization and Optimization of Cu-Al2O3 Nanocomposites Synthesized via High Energy Planetary Milling: A Morphological and Structural Study

“…In particular, the production of metal matrix nanocomposites has gained significant attention due to their unique mechanical, thermal, and electrical properties. Copper-based nanocomposites have been studied extensively due to the high thermal and electrical conductivity of copper [1][2][3][4], as well as its low cost and availability [5,6]. The incorporation of ceramic nanoparticles, such as alumina, into the copper matrix can improve the mechanical properties [7,8], such as hardness and wear resistance, without compromising the electrical and thermal conductivity [9][10][11].…”