Bactericidal and Fungicidal Activity of Methanolic Extracts of Heracleum persicum Desf. ex Fischer against Some Aquatic and Terrestrial Animal Pathogens

Antibacterial Properties of Essential Oil of Heracleum persicum (Golpar) and Foodborne Pathogens

“…17,18 Kousha and Bayat indicated that extracts of leaves and 19 Manikandan et al 20 reported that the methanolic extract of leaves of different plants were more active than the aqueous extract in presence of Bacillus subtilis, Bacillus pumilus, Micrococcus luteus and S. aureus.…”

Bioactivity-guided isolation of antimicrobial coumarins from Heracleum mantegazzianum Sommier & Levier (Apiaceae) fruits by high-performance counter-current chromatography

“…Based on these data, the antibacterial and antifungal activity of Heracleum species is likely to be due to the presence of furanocoumarins (Ozçelik, Kusmenoglu, Turkoz, & Abbasoglu, 2004). This is why plants from Heracleum genus are used as food preservatives, spice and flavoring agents, as well as a carminative, digestive, and analgesic (Firuzi, Asadollahi, Gholami, & Javidnia, 2010;Kousha & Bayat, 2012;Radjabian, Salimi, Rahmani, Shockravi, & Mozaffarian, 2013).…”

“…The methanolic extract of Heracleum maximum W. Bartram roots, and the furanocoumarins bergapten, isobergapten, angelicin, sphondin, pimpinellin, isopimpinellin and 6-isopentenyloxyisobergapten, showed strong antimycobacterial activity (O'Neill et al, 2013). In addition, Kousha and Bayat (2012) observed that the ethanolic extract of flowers and leaves of Heracleum persicum Desf. ex Fisch.…”

“…At the same time it is known that antimicrobial substances from natural sources have been investigated to achieve higher levels of food safety (Sakunpak & Panichayupakaranant, 2012). Extracts of the different Heracleum genus are widely used in the treatment of bacterial diseases in traditional medicine (Kousha & Bayat, 2012;O'Neill, Johnson, Webster, & Gray, 2013). The methanolic extract of Heracleum maximum W. Bartram roots, and the furanocoumarins bergapten, isobergapten, angelicin, sphondin, pimpinellin, isopimpinellin and 6-isopentenyloxyisobergapten, showed strong antimycobacterial activity (O'Neill et al, 2013).…”

The effect of hydroalcoholic extract of angelica (Heracleum persicum) fruit on performance, immune responses, small intestine histology, haematological parameters and carcass characteristics of broiler chickens

“…A number of chemical constituents, such as alkaloids, volatile substances, terpenoids, triterpenes and furanocoumarins have been isolated from fruit and different part of the plant (Sefidkon et al 2002;Mojab and Nickavar 2003;Sefidkon et al 2004;Hajhashemi et al 2009). Because of the diversity of phytochemicals that are present in this plant, several evidence have shown the antimicrobial (Kousha and Bayat 2012), immunostimulatory (Sharififar et al 2009;Naeini et al 2013), lipid-modifying (Panahi et al 2011), anti-inflammatory (Hajhashemi et al 2009), anticonvulsant (Sayyah et al 2005) and antioxidant activity (Souri et al 2004) of Heracleum persicum.…”