1951
DOI: 10.1038/168955b0
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Bacterial Enzyme Preparations oxidizing Inositol and their Inhibition by Colchicine

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1953
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Cited by 20 publications
(7 citation statements)
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“…While investigating the oxidation of cyclitols in extracts of A. 8uboxydan8 Franzl & Chargaff (1951) observed a similar effect due to a heat-stable factor present in the cells. The ions and the unidentified factor which restore the activity (measured manometrically or by anaerobic reduction offerricyanide) may be involved in some part of the hydrogenor electron-transporting mechanism other than the polyol dehydrogenase.…”
Section: Mg2+mentioning
confidence: 85%
“…While investigating the oxidation of cyclitols in extracts of A. 8uboxydan8 Franzl & Chargaff (1951) observed a similar effect due to a heat-stable factor present in the cells. The ions and the unidentified factor which restore the activity (measured manometrically or by anaerobic reduction offerricyanide) may be involved in some part of the hydrogenor electron-transporting mechanism other than the polyol dehydrogenase.…”
Section: Mg2+mentioning
confidence: 85%
“…Gluconobacter oxydans and Acetobacter suboxydans) showed that the main product of the fermentation was myo-inosose-2 (Kluyver & Boezaardt, 1939;Posternak, 1941;Carter et al, 1948). Later work (Franzl & Chargaff, 1951;Rapin et al, 1967) centred on the attempts to obtain cell-free extracts. Results showed that the inositol dehydrogenase(s) was membrane-bound, but attempts at the isolation of soluble enzyme were unsuccessful (Franzl, 1952).…”
mentioning
confidence: 99%
“…A. suboxydans possesses two systems for the oxidation of open chain polyols. (66,118) although contrary reports exist (65). The former enzyme is ap parently present in the particulate fraction of the cell (sedimentable at 20,000 g for 2 hrs.)…”
Section: Metabolismmentioning
confidence: 92%
“…The oxidation of glucose to gluconate is apparently performed by the particulate fraction of the cells and is perhaps cytochrome-linked (65,66). (63,64), also evolve CO2 from glucose but only after con sumption of three atoms of oxygen.…”
Section: Metabolismmentioning
confidence: 99%
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