“…Whilst clinical evidence of intracranial embolization is seen in 15 % of patients with bacterial endo-carditis (Cates and Christie, 1951), death attributable to this complication is much less frequent (Cates and Christie, 1951;Freidberg, Goldman and Field, 1961;Pankey, 1962;Volger, Dorney and Bridges, 1962). Experience of this patient, in whom the control of rapid atrial fibrillation was covered with heparin resulting in a fatal intracranial haemorrhage, re-emphasizes the risks when anticoagulants are given in bacterial endocarditis.…”