Abstract:The present study demonstrates that the use of CHX as an antimicrobial agent is effective in reducing the overall number of bacterial colonies in the oral cavity. Rinsing is a more effective method of doing this.
“…This is because the rinsing technique can reach areas in the oral cavity that are hard to reach such as tooth cracks. 4 In table 1 there are variations in the number of bacterial colonies in the control group using swab techniques on number 7, 9, 10, control group with a rinsing technique on number 3 and 5, and 1% povidone iodine group number 7 and 8. This is likely due to different bacterial oral cavity factors in the oral cavity for each individual so it causes the varied results.…”
Section: Discussionmentioning
confidence: 99%
“…There were group rinsed with 15 ml of 0.9% normal saline and 1% Povidone Iodine for 30 s, whereas the other group had their mouths swabbed with a gauze swab soaked in 0.9% normal saline and 1% Povidone Iodine. 4 All the participants for swab with control group and treatment group, the research subject was seated in the dental unit. Soak sterile gauze in 0.9% normal saline and 1% Povidone Iodine in a plastic cup.…”
Section: Methodsmentioning
confidence: 99%
“…When applying antimicrobial agents, two broad techniques are generally used which is mouth rinse and swabbing. 4 The oral swab technique covers the entire oral cavity, teeth, the soft tissue of the mouth including the buccal mucosa, vestibule, gingiva and floor of the mouth and the dorsum of the tongue. 5 Mouth rinse may be better than swabbing in oral decontamination, because swabbing does not achieve cleanliness of the lingual, occlusal, and interproximal surfaces.…”
Objective: To compare between effectivity of povidone iodin 1% application with swab technique and rinse to the number of bacteria colonization as an aseptic action at the
“…This is because the rinsing technique can reach areas in the oral cavity that are hard to reach such as tooth cracks. 4 In table 1 there are variations in the number of bacterial colonies in the control group using swab techniques on number 7, 9, 10, control group with a rinsing technique on number 3 and 5, and 1% povidone iodine group number 7 and 8. This is likely due to different bacterial oral cavity factors in the oral cavity for each individual so it causes the varied results.…”
Section: Discussionmentioning
confidence: 99%
“…There were group rinsed with 15 ml of 0.9% normal saline and 1% Povidone Iodine for 30 s, whereas the other group had their mouths swabbed with a gauze swab soaked in 0.9% normal saline and 1% Povidone Iodine. 4 All the participants for swab with control group and treatment group, the research subject was seated in the dental unit. Soak sterile gauze in 0.9% normal saline and 1% Povidone Iodine in a plastic cup.…”
Section: Methodsmentioning
confidence: 99%
“…When applying antimicrobial agents, two broad techniques are generally used which is mouth rinse and swabbing. 4 The oral swab technique covers the entire oral cavity, teeth, the soft tissue of the mouth including the buccal mucosa, vestibule, gingiva and floor of the mouth and the dorsum of the tongue. 5 Mouth rinse may be better than swabbing in oral decontamination, because swabbing does not achieve cleanliness of the lingual, occlusal, and interproximal surfaces.…”
Objective: To compare between effectivity of povidone iodin 1% application with swab technique and rinse to the number of bacteria colonization as an aseptic action at the
“…The proportion of Methicillin Resistant S. pseudintermedius (MRSP) among S. pseudintermedius isolates from clinical infections in the USA and Europe has risen since 2000 ( Frank and Loeffler, 2012 ) and a link between antimicrobial treatments within 30 days and MRSP infections has been identified in dogs ( Weese et al, 2012 ). Biocide resistances can also develop during chlorhexidine treatment ( Johnson et al, 2015 ). Resistance to chlorhexidine can be conferred by carriage of qac A/B or smr genes conding for efflux pumps.…”
Resistance in canine pathogenic staphylococci is necessitating re-evaluation of the current antimicrobial treatments especially for biofilm-associated infections. Long, repeated treatments are often required to control such infections due to the tolerance of bacteria within the biofilm. To comply with the goal of better antibiotic stewardship in veterinary medicine, the efficacies of the available drugs need to be directly assessed on bacterial biofilms. We compared the activities of amoxicillin, cefalexin, clindamycin, doxycycline, and marbofloxacin on in vitro biofilms of Staphylococcus pseudintermedius and Staphylococcus aureus. Exposure of biofilms for 15 h to maximum concentrations of the antibiotics achievable in canine plasma only reduced biofilm bacteria by 0.5–2.0 log10 CFU, compared to the control, except for marbofloxacin which reduced S. aureus biofilms by 5.4 log10 CFU. Two-antibiotic combinations did not improve, and even decreased, bacterial killing. In comparison, 5 min-exposure to 2% chlorhexidine reduced biofilms of the two tested strains by 4 log10 CFU. Our results showed that S. pseudintermedius and S. aureus biofilms were highly tolerant to all the drugs tested, consistent with the treatment failures observed in practice. Under our in vitro conditions, the use of chlorhexidine was more efficacious than antimicrobials to reduce S. pseudintermedius biofilm.
“…Prophylaxis antibiotics are recommended in some circumstances prior to tooth extraction, dental cleaning, dental implant surgery and dentoalveolar surgery to reduce postoperative infections [11 -14]. Among the several antiseptic agents available, Chlorhexidine (CHX) mouthwash is the gold standard for infection control due to its efficiency and wide range of antimicrobial spectrum [15]. However, using antiseptic mouthwash may not be appropriate for those allergic to the agents.…”
Background:
Antimicrobial properties of some anesthetic agents have been reported which may be useful for infection control. Topical lidociane (10%) showed some extent of antimicrobial activity on oral microflora.
Objective:
This study aimed to determine whether the antimicrobial efficiency of topical lidocaine can be enhanced by adding chlorhexidine.
Methods:
The Lidocaine-Chlorhexidine (LD-CHX) preparation was prepared by mixing 2.0% CHX and 10% LD with various ratios. The anesthetic efficiency was tested on the oral mucosa of 26 volunteers by Pin Prick Test. Pain scores were recorded using the Numerical Rating Scale (NRS). Antimicrobial effects of 10% LD, 0.2% CHX, and LD-CHX preparations were evaluated. In vitro study was conducted against seven standard bacterial strains. For in vivo study, oral biofilms of 26 volunteers were collected by imprint technique using filter papers. Bacterial growth from the samples after applying the test solutions was compared to the control. Antimicrobial efficiency was expressed as microbial reduction scores from 4-0 (highest to lowest).
Results:
The LD-CHX preparations that had comparable anesthetic efficiency to 10% LD were those containing 9% and 8% LD. These LD-CHX preparations showed microbial reduction scores of 3 and 4 on seven bacterial strains and oral biofilms.
Conclusion:
This study showed the antimicrobial and anesthetic effectiveness of new lidocaine-chlorhexidine preparations both in vitro and in vivo. We also confirmed the effectiveness of infection control protocol in oral surgery using CHX mouthwash prior to topical LD.
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