Bacterial cellulose reinforced double-network hydrogels for shape memory strand

Hua, Jiachuan; Liu, Chang; Ng, Pui Fai; Fei, Bin

doi:10.1016/j.carbpol.2021.117737

Cited by 41 publications

(19 citation statements)

References 56 publications

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“…The use of nanocellulosic materials in obtaining hydrogels from renewable materials has been a much-desired goal that has been achieved for many hydrogel types [ 47 , 48 , 49 ]. Several smart hydrogels such as injectable hydrogels [ 33 , 50 , 51 ], shape memory [ 52 , 53 ], supramolecular hydrogels [ 54 , 55 ], double-membrane hydrogels [ 56 ], temperature-sensitive hydrogels [ 57 ], and many other hydrogels types based on nanocellulose with potential for biomedical applications have been developed.…”

Section: Advanced Functional Materials Based On Nanocellulose—general Characteristicsmentioning

confidence: 99%

Advanced Functional Materials Based on Nanocellulose for Pharmaceutical/Medical Applications

Nicu¹,

Ciolacu

Ciolacu³

2021

Pharmaceutics

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Nanocelluloses (NCs), with their remarkable characteristics, have proven to be one of the most promising “green” materials of our times and have received special attention from researchers in nanomaterials. A diversity of new functional materials with a wide range of biomedical applications has been designed based on the most desirable properties of NCs, such as biocompatibility, biodegradability, and their special physicochemical properties. In this context and under the pressure of rapid development of this field, it is imperative to synthesize the successes and the new requirements in a comprehensive review. The first part of this work provides a brief review of the characteristics of the NCs (cellulose nanocrystals—CNC, cellulose nanofibrils—CNF, and bacterial nanocellulose—BNC), as well as of the main functional materials based on NCs (hydrogels, nanogels, and nanocomposites). The second part presents an extensive review of research over the past five years on promising pharmaceutical and medical applications of nanocellulose-based materials, which have been discussed in three important areas: drug-delivery systems, materials for wound-healing applications, as well as tissue engineering. Finally, an in-depth assessment of the in vitro and in vivo cytotoxicity of NCs-based materials, as well as the challenges related to their biodegradability, is performed.

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Section: Advanced Functional Materials Based On Nanocellulose—general Characteristicsmentioning

confidence: 99%

Advanced Functional Materials Based on Nanocellulose for Pharmaceutical/Medical Applications

Nicu¹,

Ciolacu

Ciolacu³

2021

Pharmaceutics

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“…However, hydrogel fibers have undesirable mechanical weaknesses and brittleness, which have limited their real uses, as has the complexity of processing flowable dope into crosslinked gel strands. In our previous work, hydrogels with high toughness have been synthesized and applied in cell cultures [ 6 ], shape memory actuators [ 7 , 8 , 9 ] and intelligent textiles [ 2 , 10 ]. Based on dynamic covalent bonding and the self-assembly of polysaccharide networks, self-healable hydrogel fibers with mechanical robustness would be attractive for the further development of hydrogel textiles.…”

Section: Introductionmentioning

confidence: 99%

Self-Healable and Super-Tough Double-Network Hydrogel Fibers from Dynamic Acylhydrazone Bonding and Supramolecular Interactions

Hua

Liu

Fei

et al. 2022

Gels

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Macroscopic hydrogel fibers are highly desirable for smart textiles, but the fabrication of self-healable and super-tough covalent/physical double-network hydrogels is rarely reported. Herein, copolymers containing ketone groups were synthesized and prepared into a dynamic covalent hydrogel via acylhydrazone chemistry. Double-network hydrogels were constructed via the dynamic covalent crosslinking of copolymers and the supramolecular interactions of iota-carrageenan. Tensile tests on double-network and parental hydrogels revealed the successful construction of strong and tough hydrogels. The double-network hydrogel precursor was wet spun to obtain macroscopic fibers with controlled drawing ratios. The resultant fibers reached a high strength of 1.35 MPa or a large toughness of 1.22 MJ/m3. Highly efficient self-healing performances were observed in hydrogel fibers and their bulk specimens. Through the simultaneous healing of covalent and supramolecular networks under acidic and heated conditions, fibers achieved rapid and near-complete healing with 96% efficiency. Such self-healable and super-tough hydrogel fibers were applied as shape memory fibers for repetitive actuating in response to water, indicating their potential in intelligent fabrics.

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“…Literature on hydrogels gives a clear picture of the development of various interpenetration networks with different structural combinations to articulate tough hydrogels. Although single network (SN) 34,35 and double network (DN) hydrogels [36][37][38] have already been applied for various applications, the synthesis of triple network (TN) hydrogels is limited due to the various problematic issues related to homogeneity of solution, viscosity, blending, precipitation, delamination and degradation caused by mixed polymer networks. It is still a challenge to fabricate a TN hydrogel with a simple procedure and a distinctive structural association that can unite all the properties of polymers and act as a matrix for conducting hydrogels.…”

Section: Introductionmentioning

confidence: 99%

Tough and flexible conductive triple network hydrogels based on agarose/polyacrylamide/polyvinyl alcohol and poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate

Azar

Dodda

Bělský

et al. 2021

Polymer International

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Herein, we demonstrate a simple and cost-effective way to fabricate conductive triple network hydrogels based on agarose (Ag), polyacrylamide (PAM) and poly(vinyl alcohol) (PVA) with a combination of physical-chemical crosslinked networks. The conductivity was generated by doping poly (3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) into the triple network matrix of Ag-PAM-PVA. All hydrogels were homogeneous in the swollen state and incorporation of PEDOT:PSS did not influence the morphology significantly on a microscale, (light microscopy and cryogenic low-vacuum SEM). On the nanoscale, small-angle X-ray scattering showed some differences between hydrogels with/without PEDOT:PSS and also between double/triple networks. The tensile and compressive properties were enhanced at a lower concentration of PEDOT:PSS, with a maximum tensile strength of 0.47 MPa, at an elongation of 119%. Fortunately, all hydrogels have shown conductivity in the range of 0.3−1.5 mS cm −1 which is comparable with the conductivity of skin tissues and hence they can be conveniently optimized for use in biosensors or other devices related to skin/internal tissues.

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Bacterial cellulose reinforced double-network hydrogels for shape memory strand

Cited by 41 publications

References 56 publications

Advanced Functional Materials Based on Nanocellulose for Pharmaceutical/Medical Applications

Advanced Functional Materials Based on Nanocellulose for Pharmaceutical/Medical Applications

Self-Healable and Super-Tough Double-Network Hydrogel Fibers from Dynamic Acylhydrazone Bonding and Supramolecular Interactions

Tough and flexible conductive triple network hydrogels based on agarose/polyacrylamide/polyvinyl alcohol and poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate

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