Bacteremic Inquilinus limosus empyema in an Australian lung transplant patient with cystic fibrosis

Goeman, Emma; Shivam, Aruna; Downton, Teesha; Glanville, Allan R.

doi:10.1016/j.healun.2015.06.013

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…Furthermore, the bacteremia suggested virulence factors involved in the invasion. Two other cases of I. limosus bacteremia have been reported previously ( 5 , 9 ).…”

mentioning

confidence: 77%

“…The airways of CF are susceptible to colonization by respiratory pathogens ( 3 ), a condition that is improved in lung transplant recipients. Nevertheless, I. limosus infection has been reported twice in lung transplant recipients ( 4 , 5 ). In 1 case, a 22 year-old woman had pulmonary infiltrates develop within a month after lung transplantation ( 4 ).…”

mentioning

confidence: 99%

“…She completely recovered with antimicrobial drug treatment; I. limosus was not isolated during 1 year of follow-up. In the second case, a 31-year-old man experienced a bacteremic lung empyema 1 month posttransplant and a contralateral lung empyema 7 months later ( 5 ). He recovered from each episode with surgery and antimicrobial treatment with ciprofloxacin and meropenem.…”

mentioning

confidence: 99%

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Inquilinus limosus Bacteremia in Lung Transplant Recipient after SARS-CoV-2 Infection

Farfour¹,

Zrounba²,

Roux³

et al. 2023

Emerg. Infect. Dis.

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Inquilinus limosus is an environmental bacterium associated with respiratory tract colonization in cystic fibrosis patients. We report a case of I. limosus bacteremia in a patient in France who received a lung transplant and experienced chronic graft dysfunction and SARS-CoV-2 infection. This case suggests I. limosus displays virulence factors associated with invasion.

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“…Furthermore, the bacteremia suggested virulence factors involved in the invasion. Two other cases of I. limosus bacteremia have been reported previously ( 5 , 9 ).…”

mentioning

confidence: 77%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Inquilinus limosus Bacteremia in Lung Transplant Recipient after SARS-CoV-2 Infection

Farfour¹,

Zrounba²,

Roux³

et al. 2023

Emerg. Infect. Dis.

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“…I. limosus was isolated from 3 LTR with early post-operative infections [ 8 , 9 , 10 ]. All of them were transplanted for CF and were previously colonized with I. limosus .…”

Section: Review Of Cases ( Table 2 )mentioning

confidence: 99%

Rarely Encountered Gram-Negative Rods and Lung Transplant Recipients: A Narrative Review

et al. 2023

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The respiratory tract of lung transplant recipients (LTR) is likely to be colonized with non-fermentative Gram-negative rods. As a consequence of the improvements in molecular sequencing and taxonomy, an increasing number of bacterial species have been described. We performed a review of the literature of bacterial infections in LTR involving non-fermentative Gram-negative rods with exclusion of Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter spp. and Burkholderia spp. Overall, non-fermenting GNR were recovered from 17 LTR involving the following genera: Acetobacter, Bordetella, Chryseobacterium, Elizabethkinga, Inquilinus, and Pandoraea. We then discuss the issues raised by these bacteria, including detection and identification, antimicrobial resistance, pathogenesis, and cross-transmission.

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“…Goeman et al described the second report of I. limosus in a LTx recipient. 66 Of interest, the organism had first been detected 11 years previously but not in 35 samples since, until the early postoperative period when it caused bacteremia, bilateral pleural effusions with empyema and subsequent thoracotomy wound dehiscence needing flap repair. Inquilinus was not cultured from endobronchial secretions.…”

Section: Other Resistant Bacteriamentioning

confidence: 99%

The Impact of Resistant Bacterial Pathogens including Pseudomonas aeruginosa and Burkholderia on Lung Transplant Outcomes

Mitchell

Glanville

2021

Semin Respir Crit Care Med

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Pseudomonas and Burkholderia are gram-negative organisms that achieve colonization within the lungs of patients with cystic fibrosis, and are associated with accelerated pulmonary function decline. Multidrug resistance is a hallmark of these organisms, which makes eradication efforts difficult. Furthermore, the literature has outlined increased morbidity and mortality for lung transplant (LTx) recipients infected with these bacterial genera. Indeed, many treatment centers have considered Burkholderia cepacia infection an absolute contraindication to LTx. Ongoing research has delineated different species within the B. cepacia complex (BCC), with significantly varied morbidity and survival profiles. This review considers the current evidence for LTx outcomes between the different subspecies encompassed within these genera as well as prophylactic and management options. The availability of meta-genomic tools will make differentiation between species within these groups easier in the future, and will allow more evidence-based decisions to be made regarding suitability of candidates colonized with these resistant bacteria for LTx. This review suggests that based on the current evidence, not all species of BCC should be considered contraindications to LTx, going forward.

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Bacteremic Inquilinus limosus empyema in an Australian lung transplant patient with cystic fibrosis

Cited by 6 publications

References 13 publications

Inquilinus limosus Bacteremia in Lung Transplant Recipient after SARS-CoV-2 Infection

Inquilinus limosus Bacteremia in Lung Transplant Recipient after SARS-CoV-2 Infection

Rarely Encountered Gram-Negative Rods and Lung Transplant Recipients: A Narrative Review

The Impact of Resistant Bacterial Pathogens including Pseudomonas aeruginosa and Burkholderia on Lung Transplant Outcomes

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