Bacteremia: The Significance of outside versus inside Hospital Origin

Skånsberg, Per; Belfrage, S. Henning; Ericson, Carl; Renmarker, K

doi:10.3109/inf.1975.7.issue-1.05

Cited by 8 publications

(1 citation statement)

References 16 publications

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“…The choice of antibiotic must be made before bacteriological results are known based on many factors, including age of the patient, history of the disease and prevailing drug sensitivity situation in the hospital. Reports of the antibiotic sensitivity pattern in bacteremia strains and clinical data from the Scandinavian countries have been made the last decade (5, 14, 15, 16,18,25). The aim of this study was to answer the following questions: What is the sensitivity to commonly used antibiotics and to newer drugs not yet used routinely?…”

Section: Introductionmentioning

confidence: 99%

Sensitivity of 523 Blood Culture Isolates to 33 Antibiotics

Ode

Forsgren

Walder

1984

Scandinavian Journal of Infectious Diseases

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523 blood culture isolates collected during 18 months (July 1980-December 1981) were analysed by the agar dilution method for sensitivity to 33 antibiotics. Breakpoints corresponding to the SIR system were used but for N-formimidoyl-thienamycin (N-f-thienamycin), azthreonam and fosfomycin serial dilutions were made. Aminoglycosides (netilmicin, gentamicin, amikacin and tobramycin) inhibited from 90 to 86% of the strains. This was comparable to the percentage inhibited by some cephalosporins (cefotaxime, cefoperazone, ceftazidime, ceftriaxone, cefuroxime, cephamandole and moxalactam) ranging from 95 to 89%. A very high number of strains (99%) were inhibited by N-f-thienamycin. By combination of certain antibiotics more than 99% of the strains could be inhibited.

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Section: Introductionmentioning

confidence: 99%

Sensitivity of 523 Blood Culture Isolates to 33 Antibiotics

Ode

Forsgren

Walder

1984

Scandinavian Journal of Infectious Diseases

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Zur Klinik septikämischer Erkrankungen

Stille

1976

Infection

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The internationally accepted term septicaemia is used to describe illnesses in which pathogenic microorganisms are present in the blood. Septicaemia should be defined according to the causative organism, the portal of entry and the underlying disease. In the last 16 years the causative organisms in 788 cases of septicaemia in our hospital were found to be gram-positive cocci in 28.1% gram-negative rods in 37.6%, and other organisms in 24.i%. Infections with Psuedomonas in particular have become more frequent in recent years. The range of causative organisms in septicaemia varies considerably with the patient groups involved. Thus patients with myeloid insufficiency contracted primarily gram-negative septicaemia. As in the past, the pathogens in endocarditis today are primarily streptococci. In hemodialysis staphylococci and gram-negative rods are shown to occur with equal frequency. The most important clinical manifestation of septicaemia is fever with rigor. The poor prognosis in gram-negative septicaemia is mainly due to the onset of septic shock. Skin colonisation is often a typical sign of septicaemia and can also sometimes serve as a diagnostic indication. Hemorrhagic pustules surrounded by a zone of inflammation are typical in septicaemia caused by meningococci or gonococci. Skin eruptions are rare in septicaemia caused by streptococci of staphylococci. Whereas skin eruptions are absent in septicaemia due to enterobacteria, they are very often present in septicaemia caused by Pseudomonas. In bacterial endocarditis a wide variety of skin lesions can occur.

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