Bacillus Infections in Patients With Cancer

Banerjee, Chandralekha; Bustamante, Carlos I.; Wharton, Rayner C.; Talley, Eric L.; Wade, James C.

doi:10.1001/archinte.1988.00380080059017

Cited by 101 publications

(26 citation statements)

References 17 publications

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“…33 B. cereus is the most frequently isolated species. 13 Two deaths occurred in the present study. In these cases, bacillus bacteraemias were thought to be major contributing factors.…”

Section: Discussionmentioning

confidence: 41%

Bacillus spp. among hospitalized patients with haematological malignancies: clinical features, epidemics and outcomes

Özkocaman

Özçelik

Rabbani

et al. 2006

Journal of Hospital Infection

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“…33 B. cereus is the most frequently isolated species. 13 Two deaths occurred in the present study. In these cases, bacillus bacteraemias were thought to be major contributing factors.…”

Section: Discussionmentioning

confidence: 41%

Bacillus spp. among hospitalized patients with haematological malignancies: clinical features, epidemics and outcomes

Özkocaman

Özçelik

Rabbani

et al. 2006

Journal of Hospital Infection

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“…Another is the central venous catheter. In a study of 24 Bacillus bacteremias in cancer patients, 12 episodes were clinically significant, and 4 of these 12 involved Hickman catheters [10]. In our observation, despite no removal of the catheter, outcome was favorable with appropriate antibiotic therapy.…”

Section: Discussionsupporting

confidence: 43%

Necrotizing Gastritis due to Bacillus cereus in an Immunocompromised Patient

et al. 2006

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Bacillus cereus is increasingly being acknowledged as a serious bacterial pathogen in immunocompromised patients. We present a case of acute necrotizing gastritis caused by B. cereus in a 37-year-old woman with acute myeloblastic leukemia, who recovered following total parenteral nutrition and treatment with imipenem and vancomycin. B. cereus was isolated from gastric mucosa and blood cultures. Up to now, no case of acute necrotizing gastritis due to this organism has been reported.

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“…The selected B. licheniformis isolates meet the requirements of good biological indicators, since they are non-fastidious, non-pathogenic [2,21], do not require special growth requirements, and have consistent D values. Strains of B. subtilis are used as biological indicators for dry-heat sterilization and chemical sterilization with ethylene oxide, while a strain of B. pumilus is used as a biological indicator for radiation sterilization [18].…”

Section: Discussionmentioning

confidence: 99%

Potential biological indicators for glutaraldehyde and formaldehyde sterilization processes

Serry

Kadry

Abdelrahman

2003

J IND MICROBIOL BIOTECHNOL

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The present study aimed to isolate, select, and evaluate bacterial isolates with potential for use as biological indicators for sterilization with glutaraldehyde and/or formaldehyde. A total of 340 local Bacillus isolates were screened for glutaraldehyde and/or formaldehyde resistance by determination of minimum inhibitory concentrations (MICs), minimum bactericidal concentrations (MBCs), and extinction time and were compared with B. subtilis (var. niger) ATCC 9372, the biological indicator for ethylene oxide sterilization, as reference. Of these, 85 isolates had glutaraldehyde MICs of 0.5% or higher, while 29 had formaldehyde MICs of 0.04% or higher. Of the 29 resistant isolates, 15 had MBCs of 0.05% or more. Extinction times were used to evaluate the bactericidal/sporicidal activity of glutaraldehyde. Eight had inactivation times of more than 5 h in 2% glutaraldehyde (pH 8), whereas 12 had inactivation times of more than 3 h in l% formaldehyde, with one isolate in common. These 19 isolates were selected and evaluated as potential biological indicators for aldehydes by determination of the decimal reduction times ( D values), compared with the reference strain. Eight glutaraldehyde-resistant isolates exhibited D values 2.0- to 3.5-fold higher than the reference strain (30 min.). Only five of 12 formaldehyde resistant isolates had D values higher than that of the reference strain. Using six resistant isolates, temperature coefficient values between 2.11 and 3.02 were obtained for 2% formaldehyde. Finally, 14 isolates were tested for potential pathogenicity and were identified to species level. All of the eight glutaraldehyde-resistant isolates, including the isolate with dual resistance, and three formaldehyde-resistant isolates were B. licheniformis, while two other formaldehyde-resistant isolates were B. cereus. Six of the selected B. licheniformis isolates are potential biological indicators for sterilization processes using aldehydes. Three can be suggested for glutaraldehyde only and three for both aldehydes.

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Bacillus Infections in Patients With Cancer

Cited by 101 publications

References 17 publications

Bacillus spp. among hospitalized patients with haematological malignancies: clinical features, epidemics and outcomes

Bacillus spp. among hospitalized patients with haematological malignancies: clinical features, epidemics and outcomes

Necrotizing Gastritis due to Bacillus cereus in an Immunocompromised Patient

Potential biological indicators for glutaraldehyde and formaldehyde sterilization processes

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