<b>Quality‐of‐Life of Pacemaker Patients</b>: A Reappraisal of Current Instruments

Stofmeel, Monique A.M.; Post, Marcel W.M.; Kelder, Johannes C.; Grobbee, Diederick E.

doi:10.1111/j.1540-8159.2000.tb00879.x

Cited by 20 publications

(29 citation statements)

References 35 publications

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“…17 Studies included were predominantly observational and a much wider range of measures was identified than has been used in the trials of dual-and single-chamber pacemakers reported later in this assessment. Disease-specific and generic measures have been used to measure quality of life in this population as well as new measures constructed from pre-existing scales for the specific purpose of measuring the impact of cardiac pacing on quality of life.…”

Section: Impact: Disability and Quality Of Lifementioning

confidence: 99%

“…Narrative, editorial, expert opinions, nonsystematic reviews (31) Preclinical studies (blood haemodynamics, blood pressure, blood compounds, etc.) (112) Studies that do not report relevant outcomes, or for non-relevant underlying disease (10) Studies with less than 48 hours' follow-up (17) Other (non-English language, abstracts, trial details reported elsewhere) (20) Studies included = 46 Studies excluded = 324 …”

Section: Appendixmentioning

confidence: 99%

“…Studies with less than 48 hours' follow-up (17) Other (non-English language, abstracts, trial details reported elsewhere) (20) Papers included = 48…”

Section: Reasons For Exclusion (More Than One Reason Is Possible)mentioning

confidence: 99%

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The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation

Castelnuovo

Steín²,

Pitt³

et al. 2005

Health Technol Assess

112

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTAThe effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation Published November 2005This report should be referenced as follows:Castelnuovo E, Stein K, Pitt M, Garside R, Payne E. The effectiveness and costeffectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation. Health Technol Assess 2005;9(43). Health Technology Assessment is indexed and abstracted in Index Medicus/MEDLINE, Excerpta Medica/EMBASE and Science Citation Index Expanded (SciSearch ® ) and Current Contents® /Clinical Medicine. NHS R&D HTA ProgrammeT he research findings from the NHS R&D Health Technology Assessment (HTA) Programme directly influence key decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC) who rely on HTA outputs to help raise standards of care. HTA findings also help to improve the quality of the service in the NHS indirectly in that they form a key c...

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Section: Impact: Disability and Quality Of Lifementioning

confidence: 99%

Section: Appendixmentioning

confidence: 99%

See 1 more Smart Citation

The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation

Castelnuovo

Steín²,

Pitt³

et al. 2005

Health Technol Assess

112

View full text Add to dashboard Cite

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“…Recommended generic measures include the Short Form Questionnaire-36 items (SF-36), a health questionnaire with 36 questions, which looks at functional health, general well-being and physical and mental health. 15 The Karolinska Questionnaire, 16 which has been validated in patients paced for bradyarrhythmia, contains 16 questions on cardiovascular symptoms relevant to pacemaker patients. The Specific Activity Scale (SAS) 17 is another disease-specific questionnaire for the functional classification of patients with cardiovascular disease (CVD).…”

Section: Measurements Of Diseasementioning

confidence: 99%

Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a systematic review and economic evaluation

Edwards¹,

Karner²,

Trevor³

et al. 2015

Health Technol Assess

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BackgroundBradycardia [resting heart rate below 60 beats per minute (b.p.m.)] can be caused by conditions affecting the natural pacemakers of the heart, such as sick sinus syndrome (SSS) and atrioventricular (AV) blocks. People suffering from bradycardia may present with palpitations, exercise intolerance and fainting. The only effective treatment for patients suffering from symptomatic bradycardia is implantation of a permanent pacemaker.ObjectiveTo appraise the clinical effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber atrial pacemakers for treating symptomatic bradycardia in people with SSS and no evidence of AV block.Data sourcesAll databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Health Technology Assessment database, NHS Economic Evaluations Database) were searched from inception to June 2014.MethodsA systematic review of the clinical and economic literature was carried out in accordance with the general principles published by the Centre for Reviews and Dissemination. Randomised controlled trials (RCTs) evaluating dual-chamber and single-chamber atrial pacemakers and economic evaluations were included. Pairwise meta-analysis was carried out. A de novo economic model was developed.ResultsOf 493 references, six RCTs were included in the review. The results were predominantly influenced by the largest trial DANPACE. Dual-chamber pacing was associated with a statistically significant reduction in reoperation [odds ratio (OR) 0.48, 95% confidence interval (CI) 0.36 to 0.63] compared with single-chamber atrial pacing. The difference is primarily because of the development of AV block requiring upgrade to a dual-chamber device. The risk of paroxysmal atrial fibrillation was also reduced with dual-chamber pacing compared with single-chamber atrial pacing (OR 0.75, 95% CI 0.59 to 0.96). No statistically significant difference was found between the pacing modes for mortality, heart failure, stroke, chronic atrial fibrillation or quality of life. However, the risk of developing heart failure may vary with age and device. The de novo economic model shows that dual-chamber pacemakers are more expensive and more effective than single-chamber atrial devices, resulting in a base-case incremental cost-effectiveness ratio (ICER) of £6506. The ICER remains below £20,000 in probabilistic sensitivity analysis, structural sensitivity analysis and most scenario analyses and one-way sensitivity analyses. The risk of heart failure may have an impact on the decision to use dual-chamber or single-chamber atrial pacemakers. Results from an analysis based on age (> 75 years or ≤ 75 years) and risk of heart failure indicate that dual-chamber pacemakers dominate single-chamber atrial pacemakers (i.e. are less expensive and more effective) in older patients, whereas dual-chamber pacemakers are dominated by (i.e. more expensive and less effective) single-chamber atrial pacemakers in younger patients. However, these results are based on a subgroup analysis and should be treated with caution.ConclusionsIn patients with SSS without evidence of impaired AV conduction, dual-chamber pacemakers appear to be cost-effective compared with single-chamber atrial pacemakers. The risk of developing a complete AV block and the lack of tools to identify patients at high risk of developing the condition argue for the implantation of a dual-chamber pacemaker programmed to minimise unnecessary ventricular pacing. However, considerations have to be made around the risk of developing heart failure, which may depend on age and device.Study registrationThis study is registered as PROSPERO CRD42013006708.FundingThe National Institute for Health Research Health Technology Assessment programme.

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“…For patients with pacemakers, the literature recommends using a specific questionnaire related to general health issues contained in a generic questionnaire [5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Correlation between quality of life, functional class and age in patients with cardiac pacemaker

Borges¹,

Barros²,

Carvalho³

et al. 2013

Revista Brasileira De Cirurgia Cardiovascular

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Objective: To evaluate whether there is a correlation between quality of life and functional class in early heart pacemaker in patients, and its relationship with age.Methods: 107 patients of both sexes (49.5% female /50.5% male) were investigated, average implant time of 6.36 months (±2.99), and average age of 69.3 years (±12.6). To assess the FC, a scale suggested by Goldman was used; for QoL the AQUAREL questionnaire was used, associated with SF-36. Statistical analysis was conducted using Spearman's correlation with 5% significance.Results: Negative correlations were observed between QoL and FC: AQUAREL in the three domains, chest discomfort (r=-0.197, P=0.042), dyspnea (r=-0.508, P=0.000), arrhythmia (r=-0.271, P=0.005), and the SF-36 in the eight domains. Regarding age, there was a negative correlation with the SF-36 Functional Capacity (r=-0.338, P=0.000) and no correlation was found with AQUAREL. Positive correlation (r=0.237, P=0.014) was observed between age and FC. Conclusion

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Quality‐of‐Life of Pacemaker Patients: A Reappraisal of Current Instruments

Cited by 20 publications

References 35 publications

The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation

The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for bradycardia due to atrioventricular block or sick sinus syndrome: systematic review and economic evaluation

Dual-chamber pacemakers for treating symptomatic bradycardia due to sick sinus syndrome without atrioventricular block: a systematic review and economic evaluation

Correlation between quality of life, functional class and age in patients with cardiac pacemaker

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