Ovarian reserve following uterine artery embolization in women of reproductive age: A preliminary report

Abstract

Hormonal findings from this study were within normal ranges, suggesting that ovarian function is not adversely affected by UAE. Women with fibroids within reproductive age may consider UAE as a treatment option.

The effects of uterine artery embolization on ovarian reserve

“…AMH is a hormone secreted by developing preantral or small antral follicles in the ovaries, and is the best hormone for the assessment of the age-related decreases in ovarian reserve. As women age, follicle number and AMH decrease; therefore, AMH level correlates better with age than FSH level, particularly in women younger than 40 years [21,24,[33][34][35].…”

“…Consequently, a number of studies have evaluated ovarian reserve after UAE for symptomatic fibroids using hormone markers and have suggested that ovarian reserve is subclinically affected in most women; however, the ovarian reserve of perimenopausal women 45 years of age and older was apparently affected [7,[12][13][14][15][16][17].There are many markers for evaluating ovarian reserve, including antral follicle count (AFC), anti-Mü llerian hormone (AMH), follicle stimulating hormone (FSH), inhibin B, estradiol (E2), and luteinizing hormone (LH) [18]; however, AMH is superior to these other markers for evaluating ovarian reserve [19,20]. Few reports have evaluated ovarian reserve based on AMH level after UAE [21,22]. Therefore, the aim of the present study was to evaluate the effects of UAE on ovarian reserve, as determined by AMH, in premenopausal women.…”

“…There are many markers for evaluating ovarian reserve, including antral follicle count (AFC), anti-Mü llerian hormone (AMH), follicle stimulating hormone (FSH), inhibin B, estradiol (E2), and luteinizing hormone (LH) [18]; however, AMH is superior to these other markers for evaluating ovarian reserve [19,20]. Few reports have evaluated ovarian reserve based on AMH level after UAE [21,22]. Therefore, the aim of the present study was to evaluate the effects of UAE on ovarian reserve, as determined by AMH, in premenopausal women.…”

Radiation Exposure During Uterine Artery Embolization: Effective Measures to Minimize Dose to the Patient

“…Comparative studies have shown UAE to be at least equal to surgical treatment in clinical and economic terms [6][7][8][9][10][11]. A feared high risk of impairment of fertility, especially a loss of ovarian reserve, has not been proven, and all major studies consistently show that women undergoing UAE have a very limited and age-dependent risk for premature menopause [12][13][14].…”

Effect on ovarian reserve using various techniques to reduce blood loss for myomectomy

“…Контрольная группа для сравнительной оценки АМГ была заим-ствована из исследования Seifer et al и пред-ставлена женщинами аналогичной возрастной категории, страдающими бесплодием, которым ЭМА не проводили. Сравнительный анализ по-казал, что уровень АМГ был ниже в основной группе больных [16,17]. В рандомизированном проспективном исследовании Hehenkamp et al, в котором женщинам из основной группы проводили ЭМА, а пациенткам из контроль-ной группы была выполнена гистерэктомия с сохранением яичников, было показано, что к снижению ОР может приводить как ЭМА, так и гистер эктомия.…”