Abstract:The outcomes were comparable regarding early hospital outcomes and rates of adverse events. Whereas postoperative freedom from major cerebrovascular events was similar, survival over long-term follow-up was significantly poorer when direct aortic cannulation was used. More investigations are needed to enable an understanding of the underlying factors for potentially higher late mortality when direct aortic cannulation is used during a surgical procedure for acute Stanford A dissection.
“…The surgical procedure for our patients suffering an AAD is already described by our group and published elsewhere. 14 The primary endpoint was long-term overall cumulative survival with up to 9-year follow up. Secondary endpoints were early postoperative clinical characteristics and complication rates.…”
Patients with elevated creatinine levels undergoing surgical repair for Stanford A AAD demonstrate higher rate of early postoperative complications. However, 30-day mortality and long-term survival in this patient cohort is not significantly impaired.
“…The surgical procedure for our patients suffering an AAD is already described by our group and published elsewhere. 14 The primary endpoint was long-term overall cumulative survival with up to 9-year follow up. Secondary endpoints were early postoperative clinical characteristics and complication rates.…”
Patients with elevated creatinine levels undergoing surgical repair for Stanford A AAD demonstrate higher rate of early postoperative complications. However, 30-day mortality and long-term survival in this patient cohort is not significantly impaired.
“…The dissection of the aortic wall is prone to extend distally and proximally. The potential risk of exacerbating the dissection and the potential risk of rupture are concerns that are expressed regarding central aortic cannulation [29, 30]. …”
Section: The General Considerations About Cannulation Strategiesmentioning
confidence: 99%
“…The theoretical advantages of this strategy are that antegrade perfusion is achieved and that only a short time is necessary to establish CPB. The major concerns in relation to the use of this technique are the rupture of the cannulation site and false lumen perfusion [29, 30, 47]. …”
Section: Cannulation Strategiesmentioning
confidence: 99%
“…This study seems to be the only comparative study with a significant number of patients that compares these two strategies [29]. They compared the results in a total of propensity-matched patients.…”
Section: Comparative Studies On Cannulation Strategies In Surgery Formentioning
confidence: 99%
“…There was no difference in the incidence of stroke (RR 0.74; 95 % CI 0.17–3.26, calculated by the authors from published data). Long-term survival was significantly worse in patients with central aortic cannulation than in those with axillary artery cannulation [29]. …”
Section: Comparative Studies On Cannulation Strategies In Surgery Formentioning
The rates of mortality and morbidity remain high in surgery for acute type A dissection. There is controversy regarding the best cannulation strategy for achieving good clinical results. Each cannulation technique has different anatomical characteristics and a different flow pattern inside the aorta during cardiopulmonary bypass. Some adverse, clinically important outcomes may be related to events at this time. Femoral artery cannulation, axillary artery cannulation, and central aortic cannulation are the three major cannulation strategies that are adopted in many centers in the world. Accumulating results from comparative studies between right axillary artery cannulation and femoral artery cannulation show that right axillary artery cannulation is associated with better clinical outcomes. However, all of the studies have been retrospective, and few studies have compared the results of other combinations of cannulation strategies. Observational studies using newer monitoring techniques clearly show that no perfusion strategy is perfect or free from complications. In summary, the evidence is insufficient to make a strong recommendation regarding cannulation strategies. Based on the fairly consistent results of retrospective studies, more surgeons are tending to switch from a retrograde perfusion strategy to adopt an antegrade perfusion strategy. Regardless of the routine cannulation strategy that is adopted, careful monitoring and a swift response to adverse events are necessary. The further accumulation of evidence is warranted.
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