Chronic gingivitis and radix also founded. For the management, patient was given the information about SCC and motivation involving her family also oral hygiene care instructions. Then the patient was referred to an Oncologist and administered of chlorine dioxide mouthwash and multivitamin. Cytological was performed and malignant squamous cells were discovered. After tumor excision, the patient refused chemotherapy, but unfortunately, she died seven months later. As a conclusion, lack of awareness and self-neglect in SCC is reflected by the extent of the tumor and it requires more aggressive treatment which tailored to patient's condition and involves co-operation of other competent colleagues.