Avian-origin H3N2 canine influenza virus circulating in farmed dogs in Guangdong, China

Su, Shuo; Chen, Ye; Zhao, Furong; Chen, Jidang; Xie, Jiexiong; Chen, Zhongming; Huang, Zhen; Hu, Yi-Ming; Zhang, Minze; Tan, Likai; Zhang, Guihong; Li, Shoujun

doi:10.1016/j.meegid.2013.05.022

Cited by 34 publications

(19 citation statements)

References 10 publications

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“…In 2012, our previous serological surveillance indicated that the infection rate of CIV H3N2 in pet dogs and farmed dogs was 5.3 and 12.22 %, respectively (Su et al, 2013). Influenza virus NS1 interacts with a diverse range of cellular factors to antagonize host antiviral defences and promote viral replication.…”

Section: Discussionmentioning

confidence: 99%

“…H3N2 CIV was first reported in 2008 among dogs in South Korea (Song et al, 2008) and was further traced back to 2006 when a highly related virus was isolated from a sick pet dog in China (Li et al, 2010). Further reports have subsequently demonstrated both intraspecies (dog-to-dog) and interspecies (dog-to-cat) transmission under natural and experimental conditions (Lin et al, 2012;Song et al, 2009Song et al, , 2011Su et al, 2013; Y. Sun et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Identification of the IFN-β response in H3N2 canine influenza virus infection

San

et al. 2016

Journal of General Virology

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Canine influenza viruses (CIVs) circulate continuously in the dog population, providing opportunities for exposure to humans and other species. Although the dog genome has been sequenced, innate immunity in dogs is not well characterized, which limits the understanding of H3N2 canine influenza virus pathogenesis. Equally, how this virus evades the canine host innate immune response to successfully establish infection remains unclear. To analyse the IFN-b response to CIV infection in Madin-Darby canine kidney cells, the canine IFN-b promoter sequence and its positive regulatory domain motifs were first cloned and identified using a luciferase reporter system. Next, we found that infection with the CIV strain GD/12 blocked the IFN-b response primarily by inhibiting the NF-k B and IFN regulatory factor 3 (IRF3) signalling pathways. Expression of GD/12 non-structural protein 1 alone was sufficient to inhibit Sendai virus-induced NF-k B and IRF3 activation by suppressing p65 and IRF3 phosphorylation, suggesting the important role of this protein in the CIV-mediated inhibition of the IFN-b response. These results suggest that inhibition of the IFN-b signalling pathway may have played a role in CIV establishment and spread in dog populations.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Identification of the IFN-β response in H3N2 canine influenza virus infection

San

et al. 2016

Journal of General Virology

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“…starting from the outbreak of equine origin H3N2 in the US, 2004 (Crawford et al, 2005). CIV subtype H3N2 have been reported in South Korea, China and Thailand (Bunpapong et al, 2014;Li et al, 2010;Lin, Zhao, Zeng, Lu, & Liu, 2012;Song et al, 2008;Su et al, 2013;Sun et al, 2013). Inter-species transmission between dogs and cats have also been reported (Kim et al, 2013).…”

Section: Canine Influenza Viruses Have Been Reported In Many Countriesmentioning

confidence: 99%

Evidence of pandemic H1N1 influenza exposure in dogs and cats, Thailand: A serological survey

Tangwangvivat

Chanvatik

Charoenkul

et al. 2018

Zoonoses and Public Health

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Influenza A virus causes respiratory disease in both humans and animals. In this study, a survey of influenza A antibodies in domestic dogs and cats was conducted in 47 animal shelters in 19 provinces of Thailand from September 2011 to September 2014. One thousand and eleven serum samples were collected from 932 dogs and 79 cats. Serum samples were tested for influenza A antibodies using a multi‐species competitive NP‐ELISA and haemagglutination inhibition (HI) assay. The NP‐ELISA results showed that 0.97% (9/932) of dogs were positive, but all cat samples were negative. The HI test against pandemic H1N1, human H3N2 and canine H3N2 showed that 0.64% (6/932) and 1.20% (1/79) of dogs and cats were positive, respectively. It is noted that all six serum samples (5 dogs and 1 cat) had antibodies against pandemic H1N1. In summary, a serological survey revealed the evidence of pandemic H1N1 influenza exposure in both dogs and cats in the shelters in Thailand.

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“…Since 2009, a novel influenza A virus (H1N1), now called A (H1N1) pdm09 influenza virus, has caused human influenza outbreaks in North America [1] and a worldwide pandemic [2][3][4]. To date, it has not only infected human, but also been reported interspecies transmission from humans to other animals, such as pigs, poultry, dogs [5][6][7].…”

mentioning

confidence: 99%

Serological report of pandemic (H1N1) 2009 infection among cats in Northeastern China in 2012-02 and 2013-03

Zhao

Liu

Yin

et al. 2014

Virol J

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BackgroundInfluenza A virus has a wide range of hosts. It has not only infected human, but also been reported interspecies transmission from humans to other animals, such as pigs, poultry, dogs and cats. However, prevalence of A (H1N1) pdm09 influenza virus infections in cats in northeastern China is unknown. Therefore, the prevalence of A (H1N1) pdm09 influenza virus infections was performed among cats in northeastern China in this study.FindingsOf all samples in this study, the overall seroprevalence of pandemic (H1N1) 2009 infection in cats was 21% (240/1140). It also showed a higher prevalence rate of pandemic(H1N1) 2009 infection in pet cats (30.6%) than roaming cats (11%) based on NT. In addition, the results also showed a trend of difference in term of species of cats and it was statistically significant.ConclusionsThis is the first survey on the seroprevalence of pandemic (H1N1) 2009 infection among cats in northeastern China. This study has observed a relatively high seroprevalence of pandemic (H1N1) 2009 among different cat populations in northeastern China, similar seroprevalence studies should be conducted elsewhere.

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Avian-origin H3N2 canine influenza virus circulating in farmed dogs in Guangdong, China

Cited by 34 publications

References 10 publications

Identification of the IFN-β response in H3N2 canine influenza virus infection

Identification of the IFN-β response in H3N2 canine influenza virus infection

Evidence of pandemic H1N1 influenza exposure in dogs and cats, Thailand: A serological survey

Serological report of pandemic (H1N1) 2009 infection among cats in Northeastern China in 2012-02 and 2013-03

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