Avène Thermal Spring Water: an active component with specific properties

Abstract

Avène Thermal Spring Water (TSW) is a natural active component characterized by a low mineral content. In vitro experiments have demonstrated the effect of Avène TSW on membrane fluidity, its antiradical and anti-inflammatory properties, its effects on many mediators involved in the immune response and its stimulating effect on keratinocyte differentiation. The clinical efficacy of the water was demonstrated at the hydrotherapy centre in chronic and disabling diseases such as atopic dermatitis but also in various settings in medical and post dermatology procedure such as photodynamic therapy or photothermolysis. All these data support the fact that the Avène TSW is an active component.

Efficacy of a global supportive skin care programme with hydrotherapy after non-metastatic breast cancer treatment: A randomised, controlled study

“…It has anti-inflammatory and immunomodulatory properties (Boisnic, Branchet-Gumila, & Segard, 2001;Castex-Rizzi, Charveron, & Merial-Kieny, 2011;Joly et al, 1998;Merial-Kieny, Castex-Rizzi, et al, 2011;Merial-Kieny, Mengual, et al, 2011), which are potentially responsible for its soothing, antipruritic and softening effects on the skin. The anti-inflammatory properties of Avène thermal spring water have been well documented in the treatment of severe skin disorders such as psoriasis, atopic dermatitis or inherited ichthyosis (Bodemer et al, 2011;Merial-Kieny, Castex-Rizzi, et al, 2011;Merial-Kieny, Mengual, et al, 2011), as well as in the healing of facial skin after laser resurfacing (Sulimovic et al, 2002). In our study, the patients also benefited from the optimal use of emollients, which, combined with thermal spring water, resulted in the complete resolution of xerosis in all patients after the thermal treatment.…”

“…A specific hydrotherapy programme-demonstrated to be of benefit to patients with severe skin conditions, such as atopic dermatitis, psoriasis and inherited ichthyosis (Bodemer et al, 2011;Merial-Kieny, Castex-Rizzi, et al, 2011;Merial-Kieny, Mengual, et al, 2011)-might therefore be of interest as a supportive treatment in breast cancer patients.…”

Clinical efficacy of Aven thermal water in dermatology

“…Помимо этого, высокотехнологичное производство, позволяющее разливать термальную воду в емкости непосред-ственно из источника, способствует полному сохра-нению всех уникальных природных свойств [5].…”

Thermal Water from Uriage-les-Bains Exerts DNA Protection, Induction of Catalase Activity and Claudin-6 Expression on UV Irradiated Human Skin in Addition to Its Own Antioxidant Properties

“…Sulphurous thermal waters for example, have shown antioxidant properties [1]- [3], DNA protective effects [1] and inhibitory activities on neutrophil elastase [2]. Other thermal waters, such as Avene thermal water, also showed antioxidant, anti-inflammatory and immunomodulating properties and were moreover able to inhibit the TNFα induced-adhesion molecules in human endothelial cells [4] [5]. "La Roche Posay" thermal water for its part is rich in selenium, and displays antioxidant, anti-inflammatory, immunodulating and anti-irritant potential [6].…”