Avaliação de eventos infecciosos oportunistas em crianças portadoras de leucemias

Gabe, Cristina; Almeida, Denise; Siqueira, Luciano de Oliveira

doi:10.1590/s1516-84842009005000017

Cited by 9 publications

(9 citation statements)

References 22 publications

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“…In the group of children with cancer, we observed a frequency of intestinal parasites of 47.1%, similar to other studies [18,35] and higher than the frequency reported for children with leukemia in South Brazil [36]; this can be explained by the higher socioeconomic development in relation to the Northeast. Regarding the specific occurrence of parasites in this group, the occurrence of B. hominis (11.4%) and G. duodenalis (8.6%) is noteworthy.…”

Section: Discussionsupporting

confidence: 91%

Performance of microscopy and ELISA for diagnosing Giardia duodenalis infection in different pediatric groups

Silva

Pacheco

Martins

et al. 2016

Parasitology International

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Section: Discussionsupporting

confidence: 91%

Performance of microscopy and ELISA for diagnosing Giardia duodenalis infection in different pediatric groups

Silva

Pacheco

Martins

et al. 2016

Parasitology International

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“…Um estudo realizado em Pernambuco 13 , no período de janeiro de 1989 a dezembro de 1999, observou maior frequência de LLA em indivíduos nas faixas etárias entre a segunda e terceira décadas de vida, resultado semelhante ao encontrado neste estudo e em outros relatados na literatura 26,27 . Considerando os casos de LH registrados no presente estudo, observou-se maior frequência em indivíduos jovens, entre 20 e 30 anos de idade, resultados semelhantes aos relatados por outros estudos 28,29 .…”

Section: Barbosa Sfc Et Al Aspectos Epidemiológicos Dos Casos De Leunclassified

Aspectos epidemiológicos dos casos de leucemia e linfomas em jovens e adultos atendidos em hospital de referência para câncer em Belém, Estado do Pará, Amazônia, Brasil

et al. 2015

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“…The immunodeficiency state caused by the disease or induced by the chemotherapy, linked to a higher susceptibility to infections, makes this neoplasm the main cause of death in developed countries and the second most common form of death by disease in developing countries [6,10,11,14,15]. The world mortality rate for leukemia patients increased by 31,6% between 2005 and 2015, however, treatment protocols have been improved throughout the years with the development of new drugs, such as Inotuzumab [16,17].…”

Section: Introductionmentioning

confidence: 99%

Acute lymphoid and myeloid leukemia in a Brazilian Amazon population: Epidemiology and predictors of comorbidity and deaths

et al. 2019

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Introduction Leukemia is the most common cancer in children and has the highest rates of incidence in industrialized countries, followed by developing countries. This epidemiologic profile can mainly be attributed to the availability of diagnostic resources. In Brazil, leukemia diagnosis is a challenge due to financial viability, lack of hemovigilance services in isolated regions and the vast size of the territory. Its incidence in the state of Amazonas has been increasing since 2010. Therefore, this study aims to describe the epidemiological pattern and spatial distribution of patients with acute lymphoid leukemia and acute myeloid leukemia in Amazonas and identify the predictors of comorbidity and death. Materials and methods A retrospective cross-sectional study was carried out based on patients’ data which was obtained from the database of a referral center for the period of 2005 to 2015. Variables included age, gender, ethnicity, civil status, schooling, income, location of residence, subtype of leukemia, comorbidities, and date of death. The spatial distribution was performed using QGIS v.2.18. Stata software was used for univariable and multivariable logistic regression to evaluate the association between both comorbidities and death for all characteristic groups of ALL and AML. Results The group that was studied was composed of 577 ALL and 266 AML patients. For both, most patients were male, with a schooling period of 1–4 years, received<1 minimum wage, and lived mostly in Manaus, followed by the municipality of Tefé. There was no association between the development of comorbidities and analyzed variables in patients with ALL. AML patients that were >60 years old and with family history of the disease had the highest risk of developing comorbidities (OR = 5.06, p = 0.038; OR = 2.44, p = 0.041, respectively). Furthermore, patients with ALL and in the 41-50-year age group had a higher risk of death (OR = 31.12; p = 0.001). No association between death and explanatory variables were found in patients with AML. In addition, significant difference was observed in time to death (chi2 = 4,098.32, p = 0.000), with 50% of patients with AML dying within two years after diagnosis, whereas in ALL, this percentual of death only is reached in approximately 5 years. Conclusion Our study describes the data of patients with acute leukemia in Amazonas, a remote region in the north of Brazil. In addition, it highlights the importance of hemovigilance in an Amazon region state, while focusing on peripheral areas which don't have prevention, diagnosis and treatment tools for this disease.

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Avaliação de eventos infecciosos oportunistas em crianças portadoras de leucemias

Cited by 9 publications

References 22 publications

Performance of microscopy and ELISA for diagnosing Giardia duodenalis infection in different pediatric groups

Performance of microscopy and ELISA for diagnosing Giardia duodenalis infection in different pediatric groups

Aspectos epidemiológicos dos casos de leucemia e linfomas em jovens e adultos atendidos em hospital de referência para câncer em Belém, Estado do Pará, Amazônia, Brasil

Acute lymphoid and myeloid leukemia in a Brazilian Amazon population: Epidemiology and predictors of comorbidity and deaths

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