Avaliação De Equinos Submetidos À Hidratação Enteral Com Soluções Eletrolíticas Isotônicas Contendo Diferentes Fontes De Energia E Cálcio

Abstract

Avaliaram-se comparativamente os efeitos de duas soluções contendo concentrações iguais de cloreto de sódio, cloreto de potássio e magnésio, porém, uma delas contendo cloreto de cálcio e dextrose (SEDex), e a outra propionato de cálcio (SEProp), sobre parâmetros clínicos, proteínas plasmáticas totais, densidade urinária, pH urinário e glicose na urina de equinos (dois machos castrados e duas fêmeas) submetidos à um delineamento crossover 4x2. Os animais foram desidratados experimentalmente com duas aplicações de furosemida na dose de 1mg kg-1, além de jejum hídrico-alimentar de 24 horas, anteriormente aos tratamentos com as soluções, as quais foram administradas por via enteral em fluxo contínuo através de sonda nasogástrica de pequeno diâmetro numa taxa de infusão de 15 mL kg-1 h-1. A desidratação induzida provocou desidratação discreta. As soluções ocasionaram expansão da volemia, diminuiu a densidade urinária e não alterou os parâmetros clínicos dos padrões de referência. Além disso, a SEProp ocasionou glicosúria.

Enteral Electrolyte Solutions With Different Osmolarities: Clinical and Laboratory Assessment in Equines

“…There was a decrease (p<0.05) at T6h with respect to T0h in the SEDext group; however, the values obtained were within the reference range [7], suggesting that this slight change possibly is due to individual variation of the animals M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT of the group. No differences were found (p>0.05) in average values of heart rate between the treatments and the treatments throughout the experimental stage (Table 2), agreeing with the studies conducted by Gomes [8] and Silveira et al [9], who found similar results to this test. Even though the difference was not significant, some animals of all treatments exhibited a heart rate slightly above the normal range [10].…”

“…The same finding was observed regarding the capillary filling time (Table 2), which was in line with studies conducted by Avanza [10] and Gomes [8]. Different results have been reported by Silveira et al [9], who observed differences between the treatments at the end of the hydration period, with higher values of respiratory rate in the treatment using electrolyte solution with calcium propionate.…”

“…Different results were found by Silveira et al [9], who used electrolyte solutions with calcium propionate and observed glycosuria in the animals, and Avanza [11], who used electrolyte solutions with glucose and maltodextrin and also detected glycosuria, emphasizing that this author used higher doses of maltodextrin than those used in the present study.…”

“…Reinforcing this hypothesis, the electrolyte solution with calcium propionate was the treatment which determined the lowest rate of plasma volume expansion, as can be seen by the total plasma protein values (Table 4), and least absorbed water from the intestinal lumen, thus favoring the onset of diarrhea. Diarrhea occurring in equines during administration of electrolyte solutions with calcium propionate have also been reported by Silveira et al [9].…”

“…In line with this hypothesis, it is observed in Table 3 that the treatment with SEProp showed lower effect on the intestinal motility. Silveira et al [9] had also reported the presence of distension and abdominal discomfort in equines during enteral hydration using enteral electrolyte solutions containing calcium propionate.…”