Avaliação da cicatrização cutânea: fluorescência e estereologia

Gondim, Roberta Marinho Falcão

doi:10.11606/t.5.2012.tde-29102012-161842

Cited by 4 publications

(30 citation statements)

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“…Thus, the finding that the G4 group obtained the highest weight gain demonstrates that local control of topical antibiotic infection established in the literature and commonly used in clinical practice may have been determinant for this fact. However, at the end of the experiment (14 days) the group G2, contaminated and treated with saline, presented weight gain similar to G4, which may reflect the interference of other variables not subject to control and measurement, such as the acceptance of diet by each animal, the degree of wound colonization by the bacteria of the induced contamination, the animal's microbiota and the environment, as well as the level of systemic involvement by the local infection (Goldim 2012).…”

Section: Discussionmentioning

confidence: 96%

“…In his thesis on the evaluation of skin healing for forensic purposes (determining the time of evolution of the wounds), Goldim (2012) presented results demonstrating the predominance of immature collagen until the 14th day of the evolution of the lesions, and only after the 20th day there was an inversion of the proportion. In the results of the present study, this proportion was observed only in the negative control group (G1), a fact that can be justified by the contamination and different treatments in the other groups since the groups treated with antibiotics (G4) and with ethanolic extract of C. pubescens were the ones with the highest amount of mature collagen.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the scientific activity of the leaf of the species Campomanesia pubescens in wound model infected by Staphylococcus aureus

et al. 2021

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There is an increasing interest in the use of herbal remedies as healing agents, due to their lower cost in relation to other drugs and the vast Brazilian fauna. The objective of this research was to evaluate the cicatrization effect of the guariroba leaf (Campomanesia pubescens) on the healing of infected wounds. We used 45 Wistar rats, distributed in five groups (n = 9) all with surgically induced skin injury, differing in the presence of contamination and treatment, with evaluation periods of 3, 7 and 14 days, being: G1- negative control without contamination, treated with Physiological Solution 0.9%; G2- control with contamination, treated with Physiological Solution 0.9%; G3 negative with contamination, treated with Carbopol in 0.5% gel; G4- positive control with contamination, treated with Colagenase at 0.6 U / g + 0.01 g Chloramphenicol; G5- positive test with contamination treated with Campomanesia pubescens at 3%, whose vehicle was Carbopol at 0.5%. The wound was made with a metal punch 8 mm in diameter, and a cutaneous fragment was removed from the animals' backs and wound infection was applied to S. aureus in groups G2 to G5. Euthanasia was performed for a lethal dose of anesthetic, and the edges of the wounds were removed for histopathological study. The fibrinoleukocytic crust was present in all animals in the groups of 3, 7 and 14 days. The contraction of the wound was also evaluated, and all groups showed low percentage of wound regression in the 3-day treatment and with 14 days presented a high percentage of regression. Of the 5 groups, the only one that presented complete epithelialization was G5. Of the 5 groups, the ones with the best epithelialization were G4 and G5. The group with the highest amount of mature collagen fibers was G4, followed by G5, and the one with the highest proportion of immature fibers was G1. At the end of the experiment, G4 was the group that gained the most weight and G1 the one that had the lowest weight gain. Guariroba leaf extract (Campomanesia pubescens) was able to promote healing in infected skin wounds similar to the group treated with antibiotics.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Evaluation of the scientific activity of the leaf of the species Campomanesia pubescens in wound model infected by Staphylococcus aureus

et al. 2021

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“…A pele é o maior órgão do corpo humano pois recobre toda a superfície corpórea, pesa aproximadamente 4,5Kg, representando 15% do peso corporal humano. Possui estruturas especializadas, flexíveis, resistentes e complexas, sendo responsável por diversas funções de importância significativa, dentre elas a transpiração, percepção, proteção física e imunológica, pigmentação, nutrição, queratogênese, defesa, metabolização, absorção, secreção, excreção e a termorregulação, pois a pele se comporta como isolante térmico, regulando a perda hídrica e de eletrólitos do organismo, resultando na conservação da temperatura corporal (FONTENELE;CARDOSO, 2011;KHAVKIN ;ELLIS, 2011;COSTA, 2016;VENUS;WATERMAN;MCNAB, 2010;NAYLOR;WHATSON ;SHERRATT, 2011;GONDIM, 2012;DA COSTA, 2016).…”

Section: Anatomia Histologia E Fisiologia Da Peleunclassified

“…A pele age como uma membrana envolvente e isolante, uma barreira física contra agressões externas, reduzindo a penetração de substancias estranhas, químicas e nocivas, protegendo contra a ação de microrganismos patogênicos e radiação ultra violeta, além da sua capacidade de regeneração tecidual, um processo complexo que visa a restauração da integridade do tecido lesionado, fator importante para o resultado no tratamento das estrias (FONTENELE; CARDOSO, 2011;KHAVKIN;ELLIS, 2011;COSTA, 2016;VENUS;WATERMAN;MCNAB, 2010;NAYLOR;WHATSON;SHERRATT, 2011;GONDIM, 2012;DA COSTA, 2016).…”

Section: Anatomia Histologia E Fisiologia Da Peleunclassified

“…Elas desempenham suas atividades de forma independente, sofrendo regulação, modelação molecular e celular ao desempenharem suas funções. A água compõe aproximadamente 70% da pele, se distribuindo pelas camadas, sendo a hipoderme a mais hidratada, possui também proteínas, lipídeos, glucídios e sais minerais (GONDIM, 2012;KHAVKIN;ELLIS, 2011;VENUS;WATERMAN ;MCNAB 2010 ;COSTA, 2016 ;DA COSTA, 2016 ;LOPES, 2017).…”

Section: Anatomia Histologia E Fisiologia Da Peleunclassified

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A eficácia do laser de dióxido de carbono (co2) fracionado no tratamento das estrias rubras e estrias albas

Souza

2021

RCMOS

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The Effectiveness of Fractionated Carbon Dioxide (Co2) Laser in the Treatment of Red Streaks and Streak Streaks

SOUZA

2024

Rev. Cient. Multidisc. Saber

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The research developed consisted of analyzing the effectiveness of fractional CO2 laser in the treatment of stretch marks. Among the main aesthetic changes in the body, this one is like stars. The stretch mark is an atrophic aesthetic lesion, caused by ahuge stretch and a consequent rupture of the collagen and elastin fibers, responsible for theelasticity of the skin. They affect a large portion of the population, being more frequent inadolescent and pregnant women, although it can also present in obese people, patients withhormonal imbalances, users of medications and patients with a genetic history. The treatmentsfor stretch marks vary according to the stage of evolution of the stretch and the phototype ofthe patient's skin. Among the most sought after is the fractional CO2 laser, its practiceconsists of promoting tissue damage through thermal damage and vaporization of cells,leading to the stimulation of neocolagenesis, with the main target being the water present inthe tissues. The purpose of the study was to evaluate the effectiveness of using fractional CO2laser in the treatment of red and white streaks, identifying its benefits, describing itsmechanism of action and analyzing the results obtained by the scientific literature. To thisend, a bibliographic search was carried out in the main databases, a virtual health library(bvs); online electronic scientific library (scielo), academic Google and lilacs. Therefore,concluding that fractional CO2 laser is effective for the treatment of stretch marks, however,attention is needed with the patient's phototype due to complications that may occur, such aspost-inflammatory hyperpigmentation, persistent hyperpigmentation, scarring, burns andKoebner syndrome.

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Avaliação da cicatrização cutânea: fluorescência e estereologia

Cited by 4 publications

References 50 publications

Evaluation of the scientific activity of the leaf of the species Campomanesia pubescens in wound model infected by Staphylococcus aureus

Evaluation of the scientific activity of the leaf of the species Campomanesia pubescens in wound model infected by Staphylococcus aureus

A eficácia do laser de dióxido de carbono (co2) fracionado no tratamento das estrias rubras e estrias albas

The Effectiveness of Fractionated Carbon Dioxide (Co2) Laser in the Treatment of Red Streaks and Streak Streaks

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