Avaliação da atividade antiúlcera de Kalanchoe pinnata (lam.) Pers (crassulaceae)

Sobreira, Flávia Carvalho; Bacchi, Elfriede Marianne

doi:10.11606/d.9.2013.tde-23052013-145846

Cited by 3 publications

(7 citation statements)

References 39 publications

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“…In a study carried out by Araújo (2017) Coutinho et al (2021), Cruz et al (2008) and Muzitano and collaborators (2011). The authors also verified the presence of quercitrin and kaempferol 3-O-α-L-arabinopyranosyl (1→2) α-Lrhamnopyranoside, which have antioxidant and anti-inflammatory properties (Araújo et al, 2018), and 4' ,5-trihydroxy-3',8-dimethoxyflavone 7-ß-D-glucopyranoside; compounds attributed to the glycolyzed quercetin, patuletin, eupafoline and kaempferol derivatives groups, all with gastroprotective activity (Sobreira, 2013).…”

Section: Hplc Analysis Of K Pinnata Fractionsmentioning

confidence: 83%

“…Chemical investigations on K. pinnata reveal the presence of compounds from different classes such as organic acids, alkaloids, fatty acids, steroids, bufadienolides, saponins, terpenes, tannins, flavones and flavonoids (Wu, et al, 2006). Among these, the most commonly found compound in K. pinnata are the flavonoids derived from quercetin (Ichikawa et al, 1986;Costa, Jossang, et al, 1994;Muzitano, 2006;El Abdellaqui, et al, 2010;Sobreira, 2013) and kaempferol (Muzitano, 2006;Tatsimo, Tamakou, et al, 2012).…”

Section: Chemical Compounds Of Kalanchoe Pinnata (Lam ) Persmentioning

confidence: 99%

“…Tatsimo (2012) used the whole dry plant, with 1.50 kg of plant material, applying the extraction technique by percolation with methanol, at room temperature, reducing the material to 148 g, this generating the yield fractions of 38.03 g (25.69%) for hexane and 34.03 g (22.99%) for ethyl acetate. In contrast, Lanna and coauthors (2019), Almeida (2019) and Sobreira (2013) used the maceration-type extraction technique. Sobreira (2013), in turn, used ethanol and water, where they compared the hydroethanolic extract (incubated for 7 days) of leaves harvested at two times of the year.…”

Section: Yield Of Fractions Obtained From K Pinnata Extractmentioning

confidence: 99%

“…In contrast, Lanna and coauthors (2019), Almeida (2019) and Sobreira (2013) used the maceration-type extraction technique. Sobreira (2013), in turn, used ethanol and water, where they compared the hydroethanolic extract (incubated for 7 days) of leaves harvested at two times of the year. The initial extract was dissolved in distilled water and passed through liquid-liquid partition, generating the following fractions, with their respective yields: chloroform with 1.1 g and 4.4 g (5.5 % and 5.6 %), acetate ethyl with 0.74 g and 2.4 g (3.7% and 4%), and aqueous with 13.6 g and 41.6 g (68% and 69.3%).…”

Section: Yield Of Fractions Obtained From K Pinnata Extractmentioning

confidence: 99%

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Determination of the chemical profile extracts obtained from Kalanchoe pinnata (Lam.) Pers native of municipality Tabatinga-AM

Alves

Santiago

Soares

et al. 2022

RSD

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Kalanchoe pinnata formerly known as Bryophyllum pinnatum , is a herbaceous species native to tropical regions such as Africa. In Brazil, it was successfully introduced and propagated, being commonly used in communities far from large capitals. The juice of the leaves is usually used in the treatment of inflammatory diseases, gastric ulcers, burns, diarrhea , vomiting, insect bites and body aches. In the literature, compounds such as anthocyanins and flavonoids are reported that have different biological activities such as antimicrobial, antioxidant, cytotoxic, antitumor, antiparasitic, antiallergic and hepatoprotective . Based on this information and considering that there are few studies on the chemical compounds of K. pinnata in Amazonas , especially in regions farther from the capital, such as in the municipality of Tabatinga. The present work aimed to determine the chemical profile of the fractions of the crude extract of K. pinnata native to the municipality of Tabatinga - AM. For this, plant material was collected from a local producer in the municipality of Tabatinga. Then the leaves were subjected to an extraction by infusion. Soon after, the crude extract obtained was fractionated with hexane, chloroform and ethyl acetate. The resulting fractions were analyzed by High Performance Liquid Chromatography (HPLC) at wavelength λ=254 nm and, using the information available in the literature, it was possible to establish a relationship between the compound quercetin 3- O -α-L- arabinopyranosyl - (1→2)-α-L- rhamnopyranoside , as responsible for the chromatographic peaks observed in the hexane, chloroform, and ethyl acetate fractions. Thus, the present study will serve as a basis for future work on the characterization of chemical compounds present in K. pinnata from the municipality of Tabatinga.

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Section: Hplc Analysis Of K Pinnata Fractionsmentioning

confidence: 83%

Section: Chemical Compounds Of Kalanchoe Pinnata (Lam ) Persmentioning

confidence: 99%

Section: Yield Of Fractions Obtained From K Pinnata Extractmentioning

confidence: 99%

Section: Yield Of Fractions Obtained From K Pinnata Extractmentioning

confidence: 99%

See 2 more Smart Citations

Determination of the chemical profile extracts obtained from Kalanchoe pinnata (Lam.) Pers native of municipality Tabatinga-AM

Alves

Santiago

Soares

et al. 2022

RSD

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“…In an experimental model of gastric ulcers, a healing and gastroprotective effect of Kalanchoe pinnata in ethyl acetate fraction extract, which has a higher concentration of flavanoids and phenolic compounds than the crude extract and aqueous fraction. of gastric ulcers (SOBREIRA, 2013).…”

Section: Introductionmentioning

confidence: 99%

Effect of Aqueous Extract of Leaves of Kalanchoe Pinnata in the Healing of Skin Wounds in Wistar Rats

Deolindo¹,

Gomes²,

Filho³

et al. 2022

JHS

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Kalanchoe pinnata is a species widely used in folk medicine in Brazil and other parts of the world. In Brazil, it is included in the list of plants of interest to the Unified Health System (Renisus). Goal: To evaluate the effect of topical application of aqueous extract of Kalanchoe pinnata in the healing of skin wounds on the back of rats. Methodology: 20 mice were used (Rattus norvergicus), of the Wistar lineage, adults, males, acquired by the study institution (UNINOVAFAPI). The animals were submitted to the production of a cutaneous wound on the back and randomly divided into three groups: Control Group (CG), consisting of 06 animals submitted to daily cleaning of the wound with saline solution; Standard Group (GP), consisting of 07 animals treated with Trofodermin® (clostebol acetate/neomycin sulfate); and Extract Group (EG), consisting of 07 animals treated with the aqueous extract ofKalanchoe pinnata. Healing was evaluated by macroscopic analysis of the evolution of the appearance of the lesion and measurement of scar retraction of the wound by digital planimetry, as well as by histological study on slides stained with hematoxylin-eosin (H.E.) considering the parameters of inflammatory cellular elements, including collagenization and reepithelialization. The project was approved by the Ethics Committee in the Use of Animals of the Centro Universitário UNINOVAFAPI (opinion nº _0002/15). Result: AThe mean area of the skin wound at the end of the treatment was significantly smaller in the EG when compared to the CG. The histological findings confirm predominantly complete epithelialization in the EG, with significantly lower infiltration of mononuclear cells (p=0.008) compared to the other groups, that is, in the healing process of the EG there was a predominance of the final stages of the healing process. Furthermore, reepithelialization in EG was significantly higher (p=0.

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Medicina: Atenção às rupturas e permanências de um discurso científico 3

Neto¹

2022

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Direitos para esta edição cedidos à Atena Editora pelos autores. Open access publication by Atena Editora Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Avaliação da atividade antiúlcera de Kalanchoe pinnata (lam.) Pers (crassulaceae)

Cited by 3 publications

References 39 publications

Determination of the chemical profile extracts obtained from Kalanchoe pinnata (Lam.) Pers native of municipality Tabatinga-AM

Determination of the chemical profile extracts obtained from Kalanchoe pinnata (Lam.) Pers native of municipality Tabatinga-AM

Effect of Aqueous Extract of Leaves of Kalanchoe Pinnata in the Healing of Skin Wounds in Wistar Rats

Medicina: Atenção às rupturas e permanências de um discurso científico 3

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