Avaliação da aderência aos anti-retrovirais em pacientes com infecção pelo HIV/Aids

Júnior, Luiz Lignani; Greco, Dirceu Bartolomeu; Carneiro, Mariângela

doi:10.1590/s0034-89102001000600001

Cited by 39 publications

(10 citation statements)

References 3 publications

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“…The data found were similar to those from other works (Lignani Júnior, Greco, Carneiro, 2001;Menezes de Pádua et al, 2006), in which adverse reactions appearance was detected, such as: nauseas, vomits, diarrhea, allergies, anemia, abdominal pains, fatigue, headache, insomnia, pruritus, exanthema, among others.…”

Section: Discussionsupporting

confidence: 89%

“…The treatment adherence is of fundamental importance in the case of acquired immunodeficiency syndrome, because incorrect drugs use is directly related to therapeutic failure and the appearance of HIV strains that are resistant to available medications (Lignani Júnior, Greco, Carneiro, 2001) In studies mentioned by Lignani Júnior, Greco e Carneiro (2001) the rate of adherence to ARV varies between 40% and 80%. In another work developed in São Paulo and mentioned by the same authors, it was found an adherence rate of 73.8%.…”

Section: Discussionmentioning

confidence: 99%

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Pharmaceutical care to pregnant women carrying human immunodeficiency virus

Romeu¹,

Paiva

Fé³

2009

Braz. J. Pharm. Sci.

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The purpose of this present study was to know the pharmacoepidemiological profile of pregnant women carrying HIV, the prevention actions against vertical transmission, and evaluate the service respecting the patients' level of satisfaction. It was developed a quali-quantitative longitudinal study, with the sample being composed by pregnant women carrying HIV attended at the Pharmaceutical Care Service of a public hospital of Fortaleza -state of Ceará, during the period between January and September, 2007. The data were collected by means of follow-up cards, patients' medical history and, finally, interviews to verify the users' level of satisfaction related to the service. Twenty seven pregnant and parturient women have participated in the study. The mean profile found was of a single woman, aged in the range between 18 and 28 years, of Caucasian race or dark colored, with familial revenue below the minimum wage, having elementary or high school, and being unemployed. It was observed that 77.8% (n=21) of patients followed all prevention strategies against maternal-infant transmission. Twenty nine drug related problems have been detected, out of which 51.7% (n=15) were resolved. The general level of satisfaction respecting the Pharmaceutical Care Service was quite satisfactory. By means of the Pharmaceutical Care Service, the pharmacist professional effectively collaborates for the correct utilization of medications, and this action results directly in a decrease of HIV vertical transmission.Uniterms: Pharmacoepidemiology. Pharmaceutical Care. HIV. Pregnant women/pharmacoepidemiological profile.Objetivou-se com o presente estudo conhecer o perfil farmacoepidemiológico das gestantes portadoras do vírus HIV, as ações de prevenção da transmissão vertical e avaliar o serviço quanto ao nível de satisfação das pacientes. Realizou-se estudo quali-quantitativo, longitudinal, sendo a amostra composta pelas gestantes portadoras do vírus HIV atendidas no Serviço de Atenção Farmacêutica de um hospital público de Fortaleza-CE, no período de janeiro a setembro de 2007. Coletaram-se os dados por meio de fichas de seguimento, prontuários das pacientes e, finalmente, entrevistas para verificar o nível de satisfação das usuárias em relação ao serviço. Participaram do estudo 27 gestantes e parturientes infectadas pelo HIV. O perfil encontrado foi de mulheres solteiras, na faixa etária de 18 a 28 anos, de cor branca ou parda, com renda familiar inferior a um salário mínimo, com ensino fundamental ou médio e desempregadas. Observou-se que 77,8% (n=21) pacientes seguiram todas as estratégias de prevenção da transmissão materno-infantil. Detectaram-se 29 problemas relacionados ao uso de medicamentos, dos quais 51,7% (n=15) foram resolvidos. O nível de satisfação geral em relação ao serviço de atenção farmacêutica foi bastante satisfatório. Por meio do serviço de atenção farmacêutica, o profissional farmacêutico colabora com a utilização correta dos medicamentos, podendo repercutir diretamente na redução da transmissão vertical do HIV.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Pharmaceutical care to pregnant women carrying human immunodeficiency virus

Romeu¹,

Paiva

Fé³

2009

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

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“…1 From a biomedical point of view the concept of adherence to an antiretroviral therapy is associated with the act of following a medical prescription, in respect to the quantity and dosage schedule of the prescribed medicines (Adão and Merighi, 2000;Lignani Júnior et al, 2001). However, apart from this definition, which strongly suggests that the patient should "obey" the doctor, the term adherence could be understood in a more comprehensive form as being not only conformance to the medical prescription, but also involving aspects subjective to the patient with regard to the medical guidance given (Lignani Júnior at al., 2001;Cardoso and Arruda, 2004).…”

Section: Adherence and Antiretroviral Therapies: Advances And Challengesmentioning

confidence: 99%

“…However, apart from this definition, which strongly suggests that the patient should "obey" the doctor, the term adherence could be understood in a more comprehensive form as being not only conformance to the medical prescription, but also involving aspects subjective to the patient with regard to the medical guidance given (Lignani Júnior at al., 2001;Cardoso and Arruda, 2004).…”

Section: Adherence and Antiretroviral Therapies: Advances And Challengesmentioning

confidence: 99%

“…Socially mitigating factors in regards to health, such as low family income (Carvalho et al, 2003), low level of education and lack of information regarding the risk of non-adherence, are factors associated to lower levels of compliance to the therapy (Carvalho et al, 2003;Bonolo et al, 2010;Nemes et al, 2000;Lignani Júnior et al, 2001). Studies done with a psychological inclination point out that people living with HIV/AIDS are particularly vulnerable to depressive processes, which in turn is associated with failures in therapy adherence (Nemes et al, 2000;Slama et al, 2006).…”

Section: Adherence and Antiretroviral Therapies: Advances And Challengesmentioning

confidence: 99%

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Será que esse remédio vai valer a pena mesmo? Estudo antropológico sobre a adesão às terapias antirretrovirais entre grupos de mútua ajuda de pessoas vivendo com HIV/aids

Picelli

Bermúdez

2014

Saude soc.

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Anthropological study carried out by ethnographic method within the members of two HIV support groups for people living with HIV/AIDS, in the city of Brasilia. The research aims to understand the potential benefits of these forms of social organization for facing the daily life with the virus and the contribution to antiretroviral adherence. The methodological approach focused on the development of ethnographic work which included techniques such as participant observation and interviews with members and group coaches. Results led to the identification of interacting mechanisms within health staff and people living with HIV/AIDS, the adoption of attitudes to deal with the drug prescription, and input provided by the group to improve adherence to ARV by highlighting the role of networking and peer support. Keywords: Adherence; Aids; Ethnography; Support Groups. Isabelle Picelli

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Randomized Controlled Trial to Evaluate the Impact of Pharmaceutical Care on Therapeutic Success in HIV-Infected Patients in Southern Brazil

et al. 2013

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A non-blinded randomized controlled trial evaluated efficacy of pharmaceutical care (PC) (Dáder method) on self-reported antiretroviral adherence and undetectable plasma viral load (UPVL), compared with usual care (UC) in HIV-positive patients in Brazil. Most were male (63 %), mean age 40.3 years (SD = 10). After 12 months, 79.8 % of those receiving PC versus 73.8 % in UC were adherent (RR 1.05, 95 % CI 0.95-1.15, P = 0.35), and 50.3 versus 49.8 % (PC vs. UC, respectively) had UPVL (RR 1.08, 95 % CI 0.97-1.20, P = 0.15). Factors associated with self-reported adherence were regular employment, UPVL, no depressive symptoms, and lower pill load in the treatment regimen. Older age, education, CD4 count <200 cells/mm(3), and shorter treatment duration were associated with UPVL. Of 94 reported drug-related problems, 43 % resolved. In subgroup analyses of patients who experienced therapeutic failure and who were non-adherent at the beginning of the trial (N = 50), no differences were found in UPVL (HR 1.35, 95 % CI 0.57-3.19). Only education level (>12 years) was independently predictive of viral suppression (HR 7.47, 95 % CI 1.69-32.91). In conclusion, PC was not associated with increased self-reported adherence to ART or UPVL in patients treated at a health care facility in southern Brazil. The study suggests, however, that PC could be effective for the subgroup of patients with poor adherence.

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Avaliação da aderência aos anti-retrovirais em pacientes com infecção pelo HIV/Aids

Cited by 39 publications

References 3 publications

Pharmaceutical care to pregnant women carrying human immunodeficiency virus

Pharmaceutical care to pregnant women carrying human immunodeficiency virus

Será que esse remédio vai valer a pena mesmo? Estudo antropológico sobre a adesão às terapias antirretrovirais entre grupos de mútua ajuda de pessoas vivendo com HIV/aids

Randomized Controlled Trial to Evaluate the Impact of Pharmaceutical Care on Therapeutic Success in HIV-Infected Patients in Southern Brazil

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