Autopsy study of spectrum of lung lesions in Tertiary care hospital

Abstract

Background: Inflammation, Infections, occupational diseases and neoplastic lesions are common in lungs. In Autopsy internal organs including lungs are studied to decide cause of death and figure out prevalence of various lung lesions. So, prophylactic prevention plan can be prepared for prevention of various lung lesions induced mortality and reducing need for invasive biopsy as well. Aim & objective: To find out frequency of various lung lesions in relation to age and sex and analyze histopathological spectrum of lung lesions. Material & Methods: Non interventional, record based cross sectional, retrospective autopsy study was done on 139 cases of lung autopsy samples at department of pathology of tertiary care hospital, Bhavnagar, Gujarat for 2 years on samples received from January 2016 to January 2018. Lungs were fixed in 10% formalin & processed. Paraffin wax embedding was done & sections stained with H&E stain. Gross and microscopic examination of samples done and diagnosis was done. All findings were recorded and tabulated. Conclusion: Pneumonia is most common observed pathological lung lesion in our study which suggest that infections of lungs are common cause for mortality. Therefore, we suggest effective implementation of measures to prevent hospital acquired pneumonia may reduce mortality. Smoking was associated in nearly 70% patients. Autopsy study of such lung lesions can provide vision to plan preventive strategy to reduce mortality due to lung pathology.

Spectrum of lung pathology in medicolegal autopsies at rural teaching hospital

“…(1) Infectious diseases have been a major contributor to top mortality and morbidity in our country. (1) The present study shows that it is the second most common pathology(28.7%), which was comparable to the studies by Goswami et al (2) and case Selvambigai et al (7) . The studies done by Shetty et al (1) and Kurawar et al (5) showed pneumonia in nearly 20% cases.…”

“…The cases not showing any specific pathology were excluded from the study. (2) were received from >75 age group. Congestion and oedema were the commonest findings in our study (30.17%).…”

“…Therefore, it is very important to determine the common cause of death and prevalence of various lung lesions to prepare a prophylactic plan for prevention of such lung lesions induced mortality. (2)…”

Study of histopathological spectrum of non-neoplastic lesions of the lung in autopsy specimen

“…3,4,6,11,[13][14][15][16] In the present study, the most affected age group was 30-39 years followed by 20-29 years which was comparable to the results of similar studies done by Patel et al, 3 Kurawar and Vasaikar, 4 and Dhruw et al 12 (Table 5). In the present study, the most common histopathological lesion was pneumonia seen in 46% of cases which was comparable to Udayshankar et al, 14 Selvambigai et al, 16 Goswami et al, 17 and Nazish et al 18 Although tuberculosis is prevalent in our India as seen in study done by Amin et al, 6 in the current study, only 4 (4%) cases were found. The reason may be attributed to early diagnosis and better cure rate and, therefore, tuberculosis being primary cause of death in only four cases.…”