Automatic Solvent Addition Funnel for Paper Chromatography

Abstract

A compact, portable COrConversion apparatus has been developed which can be attached to GLC units. It permits the separated bands to be detected as hydrocarbon bands which can be trapped for positive identification or more detailed analysis by other methods. Alternatively, the hydrocarbon bands emerging from the GLC unit may be directed into the portable COr conversion unit, converted to COg, and detected with a separate detector.The detector shown in Figure 1 uses a Sargent Model S-36400 micro combustion furnace. The furnace will heat to the desired operating temperature, 725°t o 825°C ., in 10 minutes; furthermore,

Reaction of epoxides with 4-nitrothiophenol. Its possible application for trapping and characterization of epoxides

“…At room temperature, the adduct remained as a pale yellow viscous liquid, whereas it solidified in the freezer. It had the following spectral characteristics: UV max (EtOH) 228, 340 nm (e 7880,17 200); IR (film) 3350,1590 (sh), 1585,1505, 1327, 1085, 853, 738 cm-1; NMR (Me2SO-d6) 1.2 (d, 3 H, CH3), 3.13 (d, 2 H, CH2; J = 6 Hz), 3.9 (m, 1H, CH), 5.1 (d, 1 , OH, exchangeable with D20), 7.5,8.1 (dd, 4 H, Ph H); TLC, Rf = 0.34, Anal. Caled for C9Hn03NS: C, 50.64; , 5.16.…”

“…A limiting and serious factor in the characterization of atmospheric epoxides is their relative lack of stability. Most of these compounds are highly reactive and may decompose in the atmosphere too rapidly to be detected (3). In view of this, an investigation to detect and characterize photooxidation products of the hydrocarbons, in particular their epoxides, has been undertaken.…”

The First 110 Years of Laboratory Automation: Technologies, Applications, and the Creative Scientist

“…43 Mader and Mader 43 in 1953 placed a glass reservoir and siphon assembly on a rocking arm so that as the reservoir filled, the arm rocked, a mercury switch activated, and the turntable advanced as the siphon drained the reservoir into an Erlenmeyer flask. Van Duuren 44 in 1960 used electronic control to open the siphon valves in response to a timer, noting that a problem with paper chromatography was the time necessary to allow an equilibration time for the paper and a solvent placed in a tank. Once the equilibration was complete, the developing solvent was added and the chromatography began.…”

New Fluorescence Probes for Drug–Protein Binding Studies

“…As shown in Table I, the relative intensities in methanol, dimethylacetamide, and acetone are higher than those in either more polar or more nonpolar solvents. Since the fluorescence of acridine has been known to decrease as the polarity of solvent decreases (4, 5), it is concluded that the fluorescence of I1 is essentially a combination of the fluorescence of acridine and the substitution effects. In contrast to acridine, the presence of the chloro and methoxy groups of I1 apparently causes an increase of intensity with a decrease in the polarity of the solvent as a result of an increase in its hydrophobicity.…”

“…Acridine fluoresces very weakly in cyclohexane and benzene but shows intense fluorescence in ethanol, butanol, and water (4, 5). These solvent effects were interpreted (7) to indicate that an electron of the unshared electron pair on the nitrogen atom in acridine undergoes a transition to an antibonding T molecular orbital.…”