Automated detection of bolus arrival and initiation of data acquisition in fast, three-dimensional, gadolinium-enhanced MR angiography.

Foo, Thomas K.F.; Saranathan, Manojkumar; Prince, Martin R.; Chenevert, Thomas L.

doi:10.1148/radiology.203.1.9122407

Cited by 263 publications

(113 citation statements)

References 8 publications

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“…Correct timing of the injection is important to ensure synchronization between the transit of contrast material and scanning. Methods that can be used to achieve correct timing include empirical estimation of transit time, a small test bolus of contrast agent to determine the time delay between injection and arrival of the contrast agent bolus in the target vessel, 13 automated detection of contrast bolus passage, 14 and MR fluoroscopy to observe contrast passage. 15 Contrast-enhanced MRA (CEMRA) is advantageous in displaying detailed vessel anatomy and in reducing artifacts.…”

Section: Mra: Technical Considerationsmentioning

confidence: 99%

“…8 Therefore, several investigators have addressed techniques to precisely time the image acquisition commensurate with the arrival of contrast in the aorta. [13][14][15] In addition, time-resolved CEMRA imaging techniques have been proposed to image the aorta and renal arteries, as well as to assess delays in renal enhancement due to renal artery stenosis. 16 Although these new CEMRA methods have improved image quality, results at academic medical centers may not be uniformly applicable to clinical practice.…”

Section: Renal Mramentioning

confidence: 99%

See 1 more Smart Citation

Magnetic Resonance Angiography

Yucel¹,

Anderson²,

Edelman³

et al. 1999

Circulation

124

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Section: Mra: Technical Considerationsmentioning

confidence: 99%

Section: Renal Mramentioning

confidence: 99%

Magnetic Resonance Angiography

Yucel¹,

Anderson²,

Edelman³

et al. 1999

Circulation

124

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“…More than a decade ago, basic advances were made with the intent of providing a high-quality arterial phase image. These included understanding the effect of missed timing of the acquisition to the contrast material bolus (4), development of methods to provide accurate timing (5)(6)(7), and development of centric phase encoding as a means for allowing high spatial resolution with good venous suppression (8,9). Methods were developed for time-resolved 3D acquisition (10), which in general involved a trade-off of temporal for spatial resolution (11).…”

mentioning

confidence: 99%

Peripheral Vasculature: High-Temporal- and High-Spatial-Resolution Three-dimensional Contrast-enhanced MR Angiography

Haider

Glockner²,

Stanson

et al. 2009

Radiology

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Purpose:To prospectively evaluate the feasibility of performing high-spatial-resolution (1-mm isotropic) time-resolved three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiography of the peripheral vasculature with Cartesian acquisition with projectionreconstruction-like sampling (CAPR) and eightfold accelerated two-dimensional (2D) sensitivity encoding (SENSE). Materials and Methods:All studies were approved by the institutional review board and were HIPAA compliant; written informed consent was obtained from all participants. There were 13 volunteers (mean age, 41.9; range, 27-53 years). The CAPR sequence was adapted to provide 1-mm isotropic spatial resolution and a 5-second frame time. Use of different receiver coil element sizes for those placed on the anterior-to-posterior versus left-to-right sides of the field of view reduced signal-to-noise ratio loss due to acceleration. Results from eight volunteers were rated independently by two radiologists according to prominence of artifact, arterial to venous separation, vessel sharpness, continuity of arterial signal intensity in major arteries (anterior and posterior tibial, peroneal), demarcation of origin of major arteries, and overall diagnostic image quality. MR angiographic results in two patients with peripheral vascular disease were compared with their results at computed tomographic angiography. Results:The sequence exhibited no image artifact adversely affecting diagnostic image quality. Temporal resolution was evaluated to be sufficient in all cases, even with known rapid arterial to venous transit. The vessels were graded to have excellent sharpness, continuity, and demarcation of the origins of the major arteries. Distal muscular branches and the communicating and perforating arteries were routinely seen. Excellent diagnostic quality rating was given for 15 (94%) of 16 evaluations. Conclusion:The feasibility of performing high-diagnostic-quality timeresolved 3D contrast-enhanced MR angiography of the peripheral vasculature by using CAPR and eightfold accelerated 2D SENSE has been demonstrated.

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“…Therefore, fixed scanning time delay may have deteriorated the quality of dynamic imaging in some patients. It is likely that the use of bolus tracking or test bolus techniques (10,21) may improve the detection of hypervascular lesions using ferucarbotran-enhanced MR imaging.…”

Section: Discussionmentioning

confidence: 99%

Hemodynamic characterization of focal hepatic lesions: Role of ferucarbotran‐enhanced dynamic MR imaging using T2‐weighted multishot spin‐echo echo‐planar sequence

Hori

Murakami

Kim

et al. 2006

Magnetic Resonance Imaging

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Purpose:To investigate the role of ferucarbotran-enhanced dynamic MR imaging using multishot spin-echo echo-planar sequence in the evaluation of hemodynamics of focal hepatic lesions. Materials and Methods:Sixty-three focal hepatic lesions (24 benign and 39 malignant) from 53 consecutive patients who underwent both ferucarbotran-enhanced MR imaging and dynamic computed tomography (CT) were included in this study. MR imaging was performed with a 1.5-T scanner with a phased-array coil. T2-weighted multishot spin-echo echo-planar sequences (TR/TE ϭ 1714 -2813/80 msec) were obtained during a single breathhold before and 15, 60, 120, 180, and 600 seconds after intravenous injection of ferucarbotran. The enhancement patterns of lesions were classified into three categories by a study coordinator on the basis of dynamic CT images as hypervascular, hypovascular, and hemangioma type. The study coordinator created mean contrast-to-noise ratio of lesions vs. time curves for each enhancement pattern for quantitative analyses. Moreover, three radiologists separately and blindly reviewed MR images, and then assigned three confidence scores for the three enhancement patterns to each lesion. Sensitivity, specificity, and receiver operating characteristic analyses were performed. Results:Quantitative analyses showed characteristic enhancement curves for each enhancement pattern. Mean sensitivities/specificities were 0.816/0.882, 0.897/0.863, and 0.800/0.989 for hypervascular, hypovascular, and hemangioma types, respectively. Mean areas under the receiver operating characteristic curve were 0.886 for hypervascular type and 0.913 for hypovascular type. Conclusion:Ferucarbotran-enhanced dynamic MR imaging can be used to successfully characterize the hemodynamics of focal hepatic lesions.

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Automated detection of bolus arrival and initiation of data acquisition in fast, three-dimensional, gadolinium-enhanced MR angiography.

Cited by 263 publications

References 8 publications

Magnetic Resonance Angiography

Magnetic Resonance Angiography

Peripheral Vasculature: High-Temporal- and High-Spatial-Resolution Three-dimensional Contrast-enhanced MR Angiography

Hemodynamic characterization of focal hepatic lesions: Role of ferucarbotran‐enhanced dynamic MR imaging using T2‐weighted multishot spin‐echo echo‐planar sequence

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