Autologous Fibrin Glue With Collagen Carrier During Maxillary Sinus Lift Procedure

Leighton, Y; Weber, Benjamín; Rosas, Efrén Raúl Ponce; Pinto, Nelson; Borie, Eduardo

doi:10.1097/scs.0000000000005203

Cited by 4 publications

(7 citation statements)

References 25 publications

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“…Several studies have suggested that platelet adhesion and activation are particularly affected by adsorbed fibrinogen via its direct interaction with platelet receptors [5][6][7]. Moreover, fibrinogen is clinically used in fibrin gel complex such as plate-rich fibrin (PRF) and autologous fibrin gel (AFG) to promote bone and soft tissue regeneration around titanium implants [8,9].…”

Section: Introductionmentioning

confidence: 99%

Computational Fluid Simulation of Fibrinogen around Dental Implant Surfaces

Kitajima

Hirota

Iwai

et al. 2020

IJMS

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Ultraviolet treatment of titanium implants makes their surfaces hydrophilic and enhances osseointegration. However, the mechanism is not fully understood. This study hypothesizes that the recruitment of fibrinogen, a critical molecule for blood clot formation and wound healing, is influenced by the degrees of hydrophilicity/hydrophobicity of the implant surfaces. Computational fluid dynamics (CFD) implant models were created for fluid flow simulation. The hydrophilicity level was expressed by the contact angle between the implant surface and blood plasma, ranging from 5° (superhydrophilic), 30° (hydrophilic) to 50° and 70° (hydrophobic), and 100° (hydrorepellent). The mass of fibrinogen flowing into the implant interfacial zone (fibrinogen infiltration) increased in a time dependent manner, with a steeper slope for surfaces with greater hydrophilicity. The mass of blood plasma absorbed into the interfacial zone (blood plasma infiltration) was also promoted by the hydrophilic surfaces but it was rapid and non-time-dependent. There was no linear correlation between the fibrinogen infiltration rate and the blood plasma infiltration rate. These results suggest that hydrophilic implant surfaces promote both fibrinogen and blood plasma infiltration to their interface. However, the infiltration of the two components were not proportional, implying a selectively enhanced recruitment of fibrinogen by hydrophilic implant surfaces.

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Section: Introductionmentioning

confidence: 99%

Computational Fluid Simulation of Fibrinogen around Dental Implant Surfaces

Kitajima

Hirota

Iwai

et al. 2020

IJMS

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“…Calculation of sample size was based on a difference of bone augmentation detected among autologous fi brin glue with collagen carrier during maxillary sinus lift procedure retrieved from a previous research [7]. The overall computed sample size was 10 cases using G*Power software version 3.1.9.4, to calculate sample size based on an effect size of 1.025, using 2tailed test, and a error = 0.05 and power = 80.0%.…”

Section: Sample Size Calculationmentioning

confidence: 99%

“…aUtOlOgOUS Fibrin glUE [7] anD Sticky bOnE prEparatiOn [9] Each patient had two white tubes with own blood to obtain AFG. After being centrifuged for 23 minutes at 2,700 rpm, the collected blood was divided into two sepa rate layers.…”

Section: Surgical Proceduresmentioning

confidence: 99%

Minimal invasive crestal sinus technique using autologous fibrin glue versus sticky bone with simultaneous implant insertion: a prospective study

Abdelhamid,

Amer,

Marzouk

et al. 2023

jos

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Introduction:Following tooth extraction, posterior maxilla frequently experiences bone resorption and maxil lary sinus pneumatization, resulting in resorption of bone with insufficient dimension for adequate dental implants placement. Objectives: This clinical investigation was performed to assess implant stability and radiographic outcomes us ing autologous fibrin glue (AFG) against sticky bone combined with crestal sinus lift procedure and simultaneous implant insertion. Material and methods:The study involved 12 implants in ten patients with residual bone height from 5 to 9 mm, divided into two groups. In group A, AFG was applied for maxillary sinus augmentation, while in group B, sticky bone was used for maxillary sinus augmentation. All patients were followedup clinically to evaluate im plant stability at baseline (T 0 ), third month (T 3 ), and ninth month (T 9 ) as well as radiographically to evaluate residual bone height, implant protrusion, graft apical height, and graft sinus height at same time intervals. Data were analyzed using (IBM SPSS software, version 26.0). Pvalue ≤ 0.05 was considered statistically significant. Results: A total of 10 patients (8 females, 2 males) participated in the study, with mean age ± SD of 29.83 ± 3.54 years in group A, and mean age ± SD of 32 ± 3.89 years in group B. At T 0 , T 3 , and T 9 followup, there was a statistical significance within each group (with p < 0.001 in all studied parameters). However, there were no sig nificant differences between both groups, with p = 0.843, 0.296, and 0.451 regarding implant stability, p = 0.221, 0.244, and 0.276 in graft apical height, and p = 0.435, 0.494, and 0.673 regarding graft sinus height, respectively. Conclusions: AFG can be applied as a noninferior material during sinus lifting with advantages including fewer complications, easy preparation procedure, less timeconsuming, and affordable cost.

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“…Tubes were centrifuged (12 minutes at 2700 rpm; EBA 200 centrifuge, Andreas Hetticch, Tuttlingen, Germany) to obtain the L-PRF clots. The surgical approach for lateral sinus floor elevation followed Leighton et al, 8 in brief considering the complete wear of approximately 1.0 × 1.0 cm of the bone wall of the maxillary sinus (Fig. 2B).…”

Section: Surgical Procedures and Follow-upmentioning

confidence: 99%

“…4,6 Moreover, PRF can be combined successfully with other biomaterials such as collagen membranes and bone graft materials. 7,8 Platelet-rich fibrin acts by the release of growth factors, stimulating cell proliferation, angiogenesis and consequently bone repair and regeneration.…”

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confidence: 99%

Simultaneous Implant Placement and Sinus Lift Using Leukocyte-Platelet Rich Fibrin: A Retrospective 40-Month Study

Leighton

Rosas

Souza

et al. 2022

Journal of Craniofacial Surgery

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: The aim of this study was to report the 40-month clinical radiographical outcomes of maxillary sinus floor augmentation using leukocyte-platelet rich fibrin (L-PRF) as a single graft in combination with immediately placed implants. Twenty partially edentulous individuals with missing teeth in the region associated to maxillary sinus were included in this retrospective study. A lateral sinus floor elevation was performed considering a complete wear of the bone wall of the maxillary sinus and immediately placing the implant and filled the maxillary sinus with L-PRF clots as a single graft. After 5 months, all the implants received single screwed implant-supported prostheses. Subsequent evaluation was every 4 months assessing the success rate and biological complications. Two maxillary sinus membrane were perforated and covered with L-PRF clots. The mean bone height gain was 62.6%, observing a 100% of success and that in all the cases achieved at least the implant height. In conclusion, the use of platelet-rich fibrin clot as a single graft biomaterial during the maxillary sinus lift procedure combined with immediate implant placement may be a reliable clinical alternative, even to repair the sinus membrane.

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Autologous Fibrin Glue With Collagen Carrier During Maxillary Sinus Lift Procedure

Cited by 4 publications

References 25 publications

Computational Fluid Simulation of Fibrinogen around Dental Implant Surfaces

Computational Fluid Simulation of Fibrinogen around Dental Implant Surfaces

Minimal invasive crestal sinus technique using autologous fibrin glue versus sticky bone with simultaneous implant insertion: a prospective study

Simultaneous Implant Placement and Sinus Lift Using Leukocyte-Platelet Rich Fibrin: A Retrospective 40-Month Study

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