Autologous Fat Grafting for Correction of Unaesthetic Scars

Abstract

Autologous fat grafting is a good method for correction of retracted or sunken scars instead of the traditional scar surgical excision.

The Use of Autologous Fat Grafting for Treatment of Scar Tissue and Scar-Related Conditions

“…39,[45][46][47] The levels of evidence were II in five studies, 33,36,39,41,45 III in seven studies, [23][24][25][26]38,42,44 and IV in 14 studies. 22,23,[28][29][30]32,34,35,37,40,43,[46][47][48] Four randomized controlled trials, 33,36,39,45 16 prospective cohort studies, 22,[25][26][27]29,30,32,34,35,37,38,[41][42][43][44]46 and six retrospective cohort studies …”

“…Seven studies showed a statistically significant res ult, [25][26][27]33,41,42,44 and 19 studies did not report any statistical analyses. [22][23][24][28][29][30][31][32][34][35][36][37][38][39][40]43,[45][46][47] …”

“…[23][24][25][26][27]29,30,32,35,37,[40][41][42][44][45][46][47] Although more procedures maintain the histologic structure, Pu et al 57 described that the Coleman technique creates a higher percentage of viable adipocytes and sustains a more optimal level of cellular function within the harvested fat grafts. Gentile et al 25 described the use of stromal vascular cell fractionenhanced autologous fat grafting according to the Coleman technique.…”

Evidences of autologous fat grafting for the treatment of keloids and hypertrophic scars

“…[1][2][3][4][6][7][8][9][10][11][12][13][14][15][16] Nine of the 15 studies were classified as level IV (case series), two as level III (a retrospective cohort and a comparative clinical study), one as level II (prospective cohort study), and three were not classified (for dealing with animal studies or review articles). No level I studies were found, that is, those with the strongest evidence (controlled and randomized clinical trials).…”

“…In this context, autologous fat grafting represents another therapeutic option and has been used on unsightly and retracted scars, 1,2 burn sequelae, 3 and in reconstructive and cosmetic surgeries (to improve body contour, with the intention of filling and increasing volume).…”