Auricular Cartilage Grafting to Correct Lower Conjunctival Fornix Retraction and Eyelid Malposition in Anophthalmic Patients

Smith, Ricardo J.; Malet, T.

doi:10.1097/iop.0b013e31815efe35

Cited by 35 publications

(19 citation statements)

References 30 publications

(16 reference statements)

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“…Previously, use of auricular cartilage grafting has been used in follow-up study to treat anophthalmic patients of different ages for eyelid malposition and inferior fornix retraction. More than 90% of patients attained successful correction [122]. Satisfactory results have been reported in anophthalmic patients treated with auricular cartilage graft for lower lid retraction [123].…”

Section: Clinical Applicationsmentioning

confidence: 99%

Applications of Chondrocyte-Based Cartilage Engineering: An Overview

Phull

Abbas

et al. 2016

BioMed Research International

105

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Chondrocytes are the exclusive cells residing in cartilage and maintain the functionality of cartilage tissue. Series of biocomponents such as different growth factors, cytokines, and transcriptional factors regulate the mesenchymal stem cells (MSCs) differentiation to chondrocytes. The number of chondrocytes and dedifferentiation are the key limitations in subsequent clinical application of the chondrocytes. Different culture methods are being developed to overcome such issues. Using tissue engineering and cell based approaches, chondrocytes offer prominent therapeutic option specifically in orthopedics for cartilage repair and to treat ailments such as tracheal defects, facial reconstruction, and urinary incontinence. Matrix-assisted autologous chondrocyte transplantation/implantation is an improved version of traditional autologous chondrocyte transplantation (ACT) method. An increasing number of studies show the clinical significance of this technique for the chondral lesions treatment. Literature survey was carried out to address clinical and functional findings by using various ACT procedures. The current study was conducted to study the pharmacological significance and biomedical application of chondrocytes. Furthermore, it is inferred from the present study that long term follow-up studies are required to evaluate the potential of these methods and specific positive outcomes.

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Section: Clinical Applicationsmentioning

confidence: 99%

Applications of Chondrocyte-Based Cartilage Engineering: An Overview

Phull

Abbas

et al. 2016

BioMed Research International

105

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“…31 When using the external or anterior approach, resection of the skin and especially preaponeurotic fat should be avoided or kept to a minimum as this can worsen superior sulcus syndrome. 3,34,35,36,37 Worldwide, mucous membrane grafting is the preferred surgical technique for contracted socket. 27,32,33 Regardless of approach, care should be taken to avoid surgically overcorrecting the upper eyelid as this cannot be finetuned with the prosthesis.…”

Section: Resultsmentioning

confidence: 99%

Anophthalmic Syndrome

Shah

Hughes²,

Kirzhner

2014

Ophthalmic Plastic &Amp; Reconstructive Surgery

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“…Furthermore, various spacers have been used to lengthen the posterior lamella of the lower lids; autologous grafts have included the hard palate mucosa, tarsus, oral mucosa membrane, dermis fat, radial forearm free flap [7–12], chondrocutaneous graft, and auricular cartilage graft [13–15]. Homologous grafts, such as amniotic membrane grafts, sclera, and fascia lata [16, 17], have also been applied as spacers to reconstruct retracted lower lids.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Results of Autologous Auricular Cartilage Graft Applied in Anophthalmic Orbits Unable to Wear Prosthesis

Liao

Tsai

2019

Journal of Ophthalmology

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In anophthalmic patients, shallow lower fornices make wearing ocular prostheses impossible and maintaining normal social activities difficult. This study retrospectively investigated the long-term surgical outcomes of autologous auricular cartilage grafting for contracted orbits. From 1995 to 2013, 29 anophthalmic contracture sockets with inadequate lower fornices and poor prosthesis retention presented to Chang Gung Memorial Hospital in Linkou, Taiwan, were treated using this surgical method. The success rate, aesthetic outcome, recurrence, and complications were analyzed. Among the 29 patients, 15 were women, 14 were men, their mean age was 45 years, and the mean follow-up time was 52 months (range = 6–159 months). Satisfactory lid position was achieved in 25 cases (86%), and lower fornix retraction recurred in four cases (14%). Neither donor site morbidity nor auricular deformity was noted during the follow-up period. Therefore, an auricular cartilage graft can be used successfully as a compatible spacer for anophthalmic patients with shallow lower fornices and prosthesis-fitting problems in long-term follow-up.

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Auricular Cartilage Grafting to Correct Lower Conjunctival Fornix Retraction and Eyelid Malposition in Anophthalmic Patients

Abstract: Inferior fornix retraction and eyelid malposition in anophthalmic patients can be successfully treated with posterior lamella lengthening using an auricular cartilage graft.

Cited by 35 publications

References 30 publications

Applications of Chondrocyte-Based Cartilage Engineering: An Overview

Applications of Chondrocyte-Based Cartilage Engineering: An Overview

Anophthalmic Syndrome

Long-Term Results of Autologous Auricular Cartilage Graft Applied in Anophthalmic Orbits Unable to Wear Prosthesis

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