Auditory Evoked Potentials in Bacterial Meningitis

Kotagal, Suresh; Rosenberg, Cheri; Rudd, Donna; Dunkle, Lisa M.; Horenstein, Simon

doi:10.1001/archneur.1981.00510110053007

Cited by 43 publications

(13 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Neither age nor sex affected hearing outcome. This is in agreement with most previously reported studies (8,12,21,24,26). Fortnum found a greater risk of hearing loss in children less than one month or greater than 5 years old (9).…”

Section: Discussionsupporting

confidence: 94%

“…Hearing loss was most common following pneumococcal meningitis, a finding in keeping with most other reported studies (6,7,(23)(24)(25). Fortnum et al found no differential risk of hearing impairment by causative agent in one study from Nottingham, UK (9).…”

Section: Discussionsupporting

confidence: 77%

“…Other studies have not reported this (4,8,9,24,(29)(30)(31). However, the Todd Herson score for bacterial meningitis uses a low WBC/cmm of CSF AUDIOLOGICAL MEDICINE 2004 (<1000/cmm) as one of its prognostic indices of a poor outcome (32).…”

Section: Discussionmentioning

confidence: 90%

See 2 more Smart Citations

Hearing loss in Malawian children after bacterial meningitis: incidence and risk factors

Forsyth¹,

Kalumbi

Mphaka

et al. 2004

Audiological Medicine

View full text Add to dashboard Cite

We had an objective to describe the incidence and risk factors for hearing loss following acute bacterial meningitis in children admitted to the Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi. A double-blind placebo-controlled trial was designed from July 1997-March 2001 to determine whether early steroid therapy would reduce overall mortality and morbidity in childhood bacterial meningitis. The QECH, Blantyre, Malawi is a teaching and referral public hospital that serves the Blantyre area and receives referrals from throughout southern Malawi. Participants were children aged 2 months to 13 years, admitted with a diagnosis of bacterial meningitis, and the main outcome measures were mortality and morbidity following bacterial meningitis. Three hundred and ninety-nine of 598 (66.7%) children survived; 33.6% were due to S. pneumoniae, 30% to Haemophilus influenzae type b, 15% to Neisseria meningitides, and 16% had no growth on CSF culture. Two hundred and sixty-eight (67%) survivors had reliable hearing tests of whom 38% had impaired hearing, 77% of which was bilateral. Independent risk factors for hearing loss were the causative agent, presentation with a low coma score (52% vs. 34%, p = 0.006), a first CSF sample with a positive Gram stain for bacteria (65% vs. 44.3%, p = 0.003), a WBC < 100/cmm (p = 0.01), or a high protein level (50% if > 2000 mg/dl vs. 11% if <100 mg/dl). Associated neurological sequelae were highly associated with hearing impairment (p = 0.000012). We conclude that bacterial meningitis is the cause of many children's hearing impairment. Immunization against S. pneumoniae and H. influenzae would prevent many cases. Better first line antibiotics may reduce audiological damage. Deaf children in poorer parts of the world need more and vocal advocacy.

show abstract

Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 77%

See 1 more Smart Citation

Hearing loss in Malawian children after bacterial meningitis: incidence and risk factors

Forsyth¹,

Kalumbi

Mphaka

et al. 2004

Audiological Medicine

View full text Add to dashboard Cite

show abstract

“…10 19 24-26 The three studies that reported values gave a statistically significant raised risk at concentrations of <0-6 mmol/1,25 <11 mmol/l,'0 and <2-15 mmol/l.8 The presence of ataxia or vestibular disturbance also indicates a child at a higher risk of hearing impairment.20 27 28 However, this is likely to be a correlated effect rather than a useful causal predictor and is, anyway, difficult to recognise in very young, very sick infants. Most studies-agree that a raised cerebrospinal fluid white cell count8 10 [29][30][31] is not predictive of hearing impairment. CAUSATIVE ORGANISM Different risks have been reported from different organisms,5 18 particularly a higher risk of hearing impairment after infection with Streptococcus pneumoniae.…”

Section: Clinical Signsmentioning

confidence: 99%

Hearing impairment after bacterial meningitis: a review.

Fortnum¹

1992

Archives of Disease in Childhood

159

View full text Add to dashboard Cite

“…1981, Ozdamar and Kraus 1983, Shannon et al 1984, Stockard et al 1984. Several studies have used BAEP for .early diagnosis and evaluation of the neurological and hearing impairments of children with or recovering from bacterial meningitis (Kotagal et al 1981, Ozdamar and Kraus 1983, Ozdamar et al 1983, Vienny et al 1984. However, few have used BAEP to detect long-term brainstem and auditory neurophsychological development.…”

mentioning

confidence: 99%

Long‐term Impairments of Brain and Auditory Functions of Children Recovered From Purulent Meningitis

Jiang

Liu

et al. 1990

Develop Med Child Neuro

View full text Add to dashboard Cite

SUMMARY Sixty children who had recovered from purulent meningitis one to six years earlier were investigated for long‐term impairment of brain and auditory function, using brainstem auditory evoked potentials(BAEP) and developmental screening tests. Neurological and/or audiological BAEP abnormalities were found in 23 per cent of the children: 15 per cent had mild brainstem impairment and 12 per cent had hearing dysfunction. Developmental screening tests were administered to 46 children, of whom 61 per cent had normal, 22 per cent questionable and 17 per cent abnormal results. The results of the BAEP significantly correlated with those of the developmental screening tests, suggesting that the neuropsychological development of children with BAEP abnormalities was significantly delayed compared with that of children without BAEP abnormalities. The characteristic finding in a neurologically abnormal BAEP was slightly depressed amplitude of wave V, and the authors suggest that this is the most sensitive BAEP measure for the assessment of brainstem function in children recovered from meningitis. RÉSUMÉ Altérations cérébrales et des fonctions auditives à long terme après guérison d'une méningite purulente Soixante enfants ayant guéri d'une méningite purulente un ou six ans plus tôt ont été examinés à la recherche de troubles cérébraux et des fonctions auditives, à partir de potentiels évoqués auditifs du tronc cérébral (BAEPS) et des tests d'échantillonnage du développement. Des anomalies neurologiques ou audiologiques au BAEP ont été trouvées chez 23 pour cent des enfants: 15 pour cent avaient des altérations mineures du tronc cérébral et 12 pour cent présentaient un trouble de l'audition. Les tests d'échantillonnage du développement ont été administrés chez 46 enfants, parmi lesquels 61 pour cent donnaient des résultats normaux, 22 pour cent des résultats douteux et 17 pour cent des résultats anormaux. Les résultats des BAEP étaient corrélés significativement avec ceux des tests d'échantillonnage du développement suggérant que le développement neuropsychologique des enfants avec anomalies des BAEP étaient significativement retardé par comparaison avec celui des enfants ayant des BAEP normaux. Les caractéristiques fondamentales des BAEP neurologiquement anormaux étaient une légère dépression d'amplitude de l'onde 5, et les auteurs suggèrent qu'il s'agit là du paramètre le plus sensible de BAEP pour l'appréciation de la fonction du tronc cérébral chez l'enfant guérissant d'une méningite. ZUSAMMENFASSUNG Langzeitschäden der cerebralen und akustischen Funktionen nach einer eitrigen Meningitis 60 Kinder, die vor ein bis sechs Jahren eine eitrige Meningitis überstanden hatten, wurden mit akustisch evozierten Hirnstammpotentialen (BAEPs) und Entwicklungstests auf Hirnund Hörschäden untersucht. Bei 23 Prozent der Kinder fanden sich neurologische und/oder audiologische BAEP‐Veränderungen: 15 Prozent hatten leichte Hirnstammbefunde und 12 Prozent hatten Hörstörungen. 46 Kinder machten die Entwicklungstests, davon waren 61 Proze...

show abstract

Auditory Evoked Potentials in Bacterial Meningitis

Cited by 43 publications

References 2 publications

Hearing loss in Malawian children after bacterial meningitis: incidence and risk factors

Hearing loss in Malawian children after bacterial meningitis: incidence and risk factors

Hearing impairment after bacterial meningitis: a review.

Long‐term Impairments of Brain and Auditory Functions of Children Recovered From Purulent Meningitis

Contact Info

Product

Resources

About