Auditory Event-related Potentials in Children With Attention Deficit Hyperactivity Disorder

Abstract

We found that the endogenous ERPs (P3 and N2) were significantly affected in children with ADHD, compared to exogenous ERPs (N1 and P2). Increased latency of P3 suggests a slower processing speed, and decreased P3 amplitude is interpreted as disruption of inhibitory control in children with ADHD. These results indicate a neurocognitive abnormality in ADHD, as presented by a reduction in ERP response.

Event-Related Potentials Correlate with the Severity of Child and Adolescent Patients with Attention Deficit/Hyperactivity Disorder

“…Similar to the present observation, the correlation between P300 latency and age was reported to exist in normal children, but not in patients with ADHD [28]. Furthermore, P300 amplitude in ADHD is not normally increased during development, resulting in the absence of a relationship between P300 amplitude and age in ADHD patients [28,29,30]. Second, although P300 amplitude could be influenced by effort and motivation [31,32], each trial was conducted only once in the present study to get rid of such experimental bias.…”

“…First, the present study revealed that neither age nor FIQ were correlated with P300 amplitude and latency in patients with ADHD, whereas age was correlated with P300 amplitude at the Fz and Pz positions in controls. Similar to the present observation, the correlation between P300 latency and age was reported to exist in normal children, but not in patients with ADHD [28]. Furthermore, P300 amplitude in ADHD is not normally increased during development, resulting in the absence of a relationship between P300 amplitude and age in ADHD patients [28,29,30].…”

Long-term neurocognitive outcome and auditory event-related potentials after complex febrile seizures in children

“…The long-latency response is presumed to reflect the limbic system and multiple neocortical regions [20,21]. Eventrelated potential recording has been used as an electrophysiologic tool for studying the neural bases of cognitive activities and applied clinically in patients with psychopathology, neurological diseases, learning and attention disorders, dementia, memory disorders, and other cognitive deficits [21][22][23]. Changes in auditory ERP in children with complex FS have not been studied.…”

Subcortical encoding of speech cues in children with attention deficit hyperactivity disorder

“…Previous research has also revealed that subcortical auditory processing does not have a typical hardware design, but it has a plastic and adaptable nature which arises from learning effects and cognitive capabilities (Skoe and Kraus, 2010). According to event-related potentials (ERPs), individuals with ADHD have longer latencies in late auditory evoked potentials, which are interpreted as a disruption in their cortical inhibitory control (Anjana et al, 2010;Fisher et al, 2011;Senderecka et al, 2012;Tsai et al, 2012). In general, we can conclude that the timing deficits observed with ADHD are a combination of both bottom-up and top-down regulated processes.…”