2010
DOI: 10.1016/j.pnpbp.2010.03.011
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Auditory and visual P300 reflecting cognitive improvement in patients with schizophrenia with quetiapine: A pilot study

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Cited by 17 publications
(9 citation statements)
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“…It is observed from these figures that the amplitudes of P300 subcomponents of schizophrenic patients are much smaller compared to healthy subjects, which is in agreement with the existing literature [43][44][45][46]. In fact, one of the most consistent findings in schizophrenic patients is the significant reduction of P300 especially in auditory experiments [43,47]. Additionally, it can be observed that schizophrenic patients have longer P300 latency compared to healthy subjects, which is in agreement with the results of previous studies [22,43,44].…”
Section: Experimental Eeg Datasupporting
confidence: 91%
“…It is observed from these figures that the amplitudes of P300 subcomponents of schizophrenic patients are much smaller compared to healthy subjects, which is in agreement with the existing literature [43][44][45][46]. In fact, one of the most consistent findings in schizophrenic patients is the significant reduction of P300 especially in auditory experiments [43,47]. Additionally, it can be observed that schizophrenic patients have longer P300 latency compared to healthy subjects, which is in agreement with the results of previous studies [22,43,44].…”
Section: Experimental Eeg Datasupporting
confidence: 91%
“…Its amplitude indicates the degree of mobilization of effective resources when the brain processes information, and it also indicates the excitability of the brain [16]. Our results and findings of other authors indicate that the P300 latency reflects, to some extent, other aspects of the functional status of the brain, including such characteristics as sensation, attention, memory, information coding, cognitive integration rate, and other activities [17]. The amplitudes of the two P300 components did not differ significantly from each other in our study, which was probably related to the mildness of the cognitive function impairment in the VCIND patients and also to large individual differences.…”
Section: Discussionsupporting
confidence: 60%
“…Remark#3: According to [18], significant reduction of P300 particularly in auditory experiments, is one of the most consistent biological findings in schizophrenia. This work was also in agreement with the literature and it is shown that P3b has constantly lower magnitude in schizophrenic patients (compare Row b and c).…”
Section: Resultsmentioning
confidence: 86%