Audit of 10 years of referrals for fetal echocardiography

Clur, S. A.; Brussel, Peter M. van; Mathijssen, Inge B.; Pajkrt, Eva; Ottenkamp, Jaap; Bilardo, C. M.

doi:10.1002/pd.2847

Cited by 28 publications

(33 citation statements)

References 30 publications

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“…Pregnancies with an isolated fetal CHD with a high or lethal complexity score were most likely to be terminated, and this is consistent with the literature [10,25,26]. The termination rate for univentricular hearts is high in our population.…”

Section: Discussionsupporting

confidence: 80%

Fetal Heart Disease: Severity, Associated Anomalies and Parental Decision

Nell¹,

Wijngaarde²,

Pistorius

et al. 2013

Fetal Diagn Ther

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Objective: This study describes the association between the complexity of congenital cardiac and extracardiac malformations, and the parental decision of pregnancy continuation or termination. Methods: Congenital heart defects (CHD) was diagnosed by ultrasound in 251 fetuses before the 24th week (23 + 6 weeks) of gestation during the four year period from 2007 to 2010. All fetuses from the Utrecht region were referred to our center due to a strict referral pattern. The complexity and severity of the cardiac and possible extracardiac malformations were retrospectively categorized by a pediatric cardiologist and a perinatologist who were blinded to the pregnancy outcome. The groups with and without termination of pregnancy were compared using a univariate analysis and multivariate logistic regression. Results: In 119 (47%) of the 251 fetuses, parents opted for termination of pregnancy. In 103 of these cases (87%) there was a high complex or lethal cardiac, or a major or lethal extracardiac malformation. Of the 132 continued pregnancies, 42 fetuses (32%) had a high complex or lethal cardiac, or a major or lethal extracardiac malformation. There were significantly more terminations of pregnancy in case of a high or lethal complex cardiac or extracardiac anomaly (71 vs. 15%, p <0.001). Conclusion: Parents opted for termination of pregnancy significantly more often in cases with high complex cardiac and extracardiac malformations. It was rare for parents to opt for pregnancy termination in the absence of a severe cardiac or extracardiac malformation.

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Section: Discussionsupporting

confidence: 80%

Fetal Heart Disease: Severity, Associated Anomalies and Parental Decision

Nell¹,

Wijngaarde²,

Pistorius

et al. 2013

Fetal Diagn Ther

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show abstract

“…While Ozkutlu et al had the same indications arrangements like our study. [17][18][19][20] In this study, we scheduled the visits starting from 18-22 weeks of gestation, 28 weeks and 32 weeks. Best results of obtaining all of the screening views were in the first visits.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of fetal echocardiography in prenatal diagnosis of congenital heart diseases

Midan

Alsheemy

Eid

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…7,12 Improved diagnostic tools like fetal echocardiography may have led to more pregnancy terminations when severe malformations are diagnosed antenatally. 13 A reduced incidence could also be related to general improvements in reproductive health, for example related to reduced maternal smoking and improved management of morbidities such as diabetes during pregnancy. 12,14 It is not known if congenital heart defects have become less common also among infants with Down syndrome.…”

mentioning

confidence: 99%