“…Nevertheless, the coincidence in the timing of the issuance of the alert with the educational intervention, in addition to some elements of the design, 8 limited the causal attribution of the results to one or another circumstance, and therefore, they were owed presumably to an interaction between both types of intervention. 30 Focusing on interventions for prescription, several reviews on the impact of interventions on the improvement/optimization of prescribing habits [32][33][34][35] show that these can be positive, and although their impact is moderate on an individual basis, their low cost and possibility of modulation, when backed up by information, provide an enormous potential to prevent drug iatrogenic. The most effective interventions are those that are implemented in combination with other interventions, or those that are individualized, participatory, adjusted to the setting, repeated over time, with appropriate monitoring, or those with good support material.…”