Atypical radiographic features of multiple myeloma in a dog: a case report

Abstract

ABSTRACT:A 12-year-old castrated male miniature pinscher dog presented with right forelimb lameness. An expansile osteolytic lesion of the right humerus was conspicuous on right forelimb radiographs. Thoracic and abdominal radiographs showed multiple lytic bone lesions on the right scapula, ribs, vertebrae, femurs and pelvis. Additionally, an expansile osteolytic lesion was observed in two thoracic vertebrae and two ribs. Many plasma cells were identified on fine-needle aspiration of the right humerus expansile osteolytic lesion, and monoclonal gammopathy consistent with multiple myeloma was confirmed on serum protein electrophoresis. The expansile osteolytic lesion, an extraordinary radiographic feature of multiple myeloma in dogs, should be considered as a possible radiographic finding of multiple myeloma.

Subacute paraplegia in a 6-year-old spayed female Basset Hound

“…2 Metastases were observed in only thoracic and lumbar vertebral bodies and, rarely, in spinous processes, 2 but scarce descriptions were made concerning the location and the aspect of the spinous process metastases. Only 1 case report 3 described an expansile lesion in the apex of the T1 spinous process in a dog. This lesion was due to Note the severe expansile lysis of the dorsal aspect of the T6 and T7 spinous processes.…”

Computed tomographic findings in dogs with multiple myeloma

“…Most frequently affected bones are those engaged in active haematopoiesis and include the vertebral column, ribs, pelvis, skull and proximal long bones (Ettinger et al., 2016 ; Vail et al., 2019 ). Although MM shows mainly osteolytic changes on radiographs, irregular to amorphous periosteal reaction or expansile osseous lesions have also been reported (Rankin et al., 2006 ; Sung et al., 2017 ).…”