Atypical presentation of thymolipoma

Kucuk, Canan; Arda, Kemal; Ata, Naim; Türkkanı, Mustafa Hamidullah

doi:10.4081/cdr.2016.5634

Cited by 2 publications

(2 citation statements)

References 10 publications

(16 reference statements)

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“…The gender distribution has been equal (16 males and 16 females), nine cases being children with ages less than 15 years. The patients' age ranged between 6-month-old [18] and 82 years [12], as the extreme ages of patients diagnosed with thymolipoma in the mainstream publications, according to our knowledge (Figure 1).…”

Section:  Thymolipoma Incidence and Pathogenymentioning

confidence: 91%

“…Most frequently located in anterior mediastinum, thymolipoma is diagnosed in patients with ages ranging from two to 67 years, without gender predilection [8,9]. Microscopy shows a tumor mass composed by mature adipose tissue, without atypia, associated with foci of benign thymic tissue, mainly composed of epithelial cells [4,[10][11][12][13].…”

Section:  Introductionmentioning

confidence: 99%

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2021

Rom J Morphol Embryol

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Thymolipoma is an uncommon benign thymus lesion, with a partially deciphered etiopathogeny, being most frequently diagnosed in young patients, regardless of gender. Incidentally diagnosed in asymptomatic patients, larger thymolipomas lead to symptoms related to neighboring mediastinal structures compression, with an intensity which is correlated with the mass size. Our review presents the main epidemiological, pathogenic, clinicopathological and morphological characteristics of this rare pathology. Sometimes, thymolipomas may be associated with paraneoplastic syndromes, which are alleviated by the mass complete surgical resection. Imagistics may orientate the diagnosis, which is certified by the microscopic examination of the resection specimens. Extensive thymectomy remains the current therapeutic option and new tools have been developed to increase the accuracy of the surgical procedure to avoid incidental lesions of the important elements of the anterior mediastinum. Although rare, thymolipomas should be considered in the differential diagnosis of mediastinal masses and of paraneoplastic syndromes.

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Section:  Thymolipoma Incidence and Pathogenymentioning

confidence: 91%

Section:  Introductionmentioning

confidence: 99%

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2021

Rom J Morphol Embryol

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Giant thymolipoma

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Vasilyev

et al. 2020

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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Thymolipoma is a rare benign pathological tumor of the anterior mediastinum and accounts for about 2–9 % of thymus tumors. Tumor is usually represented as soft tissue consisting of adipose and thymic tissues. Because of the asymptomatic presentation, patients are often diagnosed with a large tumor. Gigantism of the tumor due to long-term and progressive compression of adjacent organs and anatomical structures of this region can lead to dysfunction, and in some cases, to a complete block of their activity, which is fraught with a fatal outcome. Preoperative diagnosis is always a difficult task due to the lower sensitivity of CT scans and biopsies. The main method of treatment is radical surgical excision. The article presents a clinical case of a 51-year-old patient with a giant tumor of the left hemithorax with a long-term asymptomatic presentation, who was diagnosed with thymolipoma after surgical excision and final histopathological examination.

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Atypical presentation of thymolipoma

Cited by 2 publications

References 10 publications

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Giant thymolipoma

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