Atypical Presentation of T-Cell Lymphoproliferative Disorder in an Oldest Old

López, Javier; Jimenez, Brenda; Galindo, Diana

doi:10.1038/ajg.2016.374

Cited by 14 publications

(2 citation statements)

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“…By study design, the association between ZIKV infection and GBS has been found at individual and population level and with different study designs. By population, ZIKV infection has been linked to GBS in ZIKV endemic regions 4– 6, 95, 96, 98– 101, 103– 105, 109, 111, 114 and travellers from non-affected countries who were exposed in these endemic regions 3, 97, 102, 106, 112 . There was insufficient evidence to examine the consistency of evidence about ZIKV and ITP.…”

Section: Resultsmentioning

confidence: 99%

Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review

et al. 2018

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The Zika virus (ZIKV) outbreak in the Americas has caused Background. international concern due to neurological sequelae linked to the infection, such as microcephaly and Guillain-Barré syndrome (GBS). The World Health Organization stated that there is "sufficient evidence to conclude that Zika virus is a cause of congenital abnormalities and is a trigger of GBS". This conclusion was based on a systematic review of the evidence published until 30.05.2016. Since then, the body of evidence has grown substantially, leading to this update of that systematic review with new evidence published from 30.05.2016 -18.01.2017, update 1.We review evidence on the causal link between ZIKV infection and Methods. adverse congenital outcomes and the causal link between ZIKV infection and GBS or immune-mediated thrombocytopaenia purpura. We also describe the transition of the review into a living systematic review, a review that is continually updated.Between 30.05.2016 and 18.01.2017, we identified 2413 Results. publications, of which 101 publications were included. The evidence added in this update confirms the conclusion of a causal association between ZIKV and adverse congenital outcomes. New findings expand the evidence base in the dimensions of biological plausibility, strength of association, animal experiments and specificity. For GBS, the body of evidence has grown during the search period for update 1, but only for dimensions that were already populated in the previous version. There is still a limited understanding of the biological pathways that potentially cause the occurrence of autoimmune disease following ZIKV infection.This systematic review confirms previous conclusions that ZIKV Conclusions. is a cause of congenital abnormalities, including microcephaly, and is a trigger of GBS. The transition to living systematic review techniques and methodology provides a proof of concept for the use of these methods to synthesise evidence about an emerging pathogen such as ZIKV. Keywords

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Section: Resultsmentioning

confidence: 99%

Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review

et al. 2018

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“…Although its efficacy remains uncertain when given preoperatively for neuroendocrine tumors, it may be a promising avenue for its impact on survival. It is clear that additional comparative diagnostic and treatment studies are needed in the future to further build guidelines for MANEC [9].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Mixed Adeno-Neuroendocrine Carcinoma of the Ileocecal Valve

Skrove

Gonzalez

Saline

et al. 2016

American Journal of Gastroenterology

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Mixed adenoneuroendocrine carcinoma (MANEC) is an uncommon neoplasm with uncertain pathophysiology. In order to be classified as MANEC, the tumor must contain at least 30% neuroendocrine cells and 30% adenocarcinoma. The standardization of MANEC treatment has historically been difficult due to the lack of diagnostic histological classification. In 2010, the World Health Organization (WHO) finally recognized this uncommon condition as a specific colon cancer entity in the hopes of better specifying treatment options in the future.We present a case of high-grade MANEC of the cecum with metastasis in 3/10 lymph nodes to further characterize the diagnostic modalities and treatment options of the disease. MANECs only account for 3%-9.6% of all colorectal cancers and only eight cases have been reported in the cecum to date, making the following case report exceptionally rare.

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Amoxicillin/clavulanic-acid/omeprazole

2016

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Atypical Presentation of T-Cell Lymphoproliferative Disorder in an Oldest Old

Cited by 14 publications

References 0 publications

Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review

Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review

A Rare Case of Mixed Adeno-Neuroendocrine Carcinoma of the Ileocecal Valve

Amoxicillin/clavulanic-acid/omeprazole

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