Atypical angiofibromas: a report of four cases

Celik, Bilge; Erişen, Levent; Saraydaroğlu, Özlem; Çoşkun, Hakan

doi:10.1016/j.ijporl.2004.10.007

Cited by 39 publications

(31 citation statements)

References 16 publications

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“…Stromal fibrosis is not excessive in haemangiomas and not seen in the capillary haemangiomas of the head and neck region. Also, anastomosing vessel architecture, which is very specific for capillary haemangiomas, is not seen in angiofibromas …”

Section: Discussionmentioning

confidence: 99%

“…Also, anastomosing vessel architecture, which is very specific for capillary haemangiomas, is not seen in angiofibromas. 83 While Peric et al 58 considered immunohistochemistry for diagnosis of ENA with a positive reaction to vimentin and CD34, and a negative reaction to actin and desmin, the author stated in a different report that angiofibromas have a positive staining for actin, too. 59 However, a positive staining for vimentin and negative staining for CD34 and actin are a typical finding in a sinunasal-type haemangiopericytoma.…”

Section: Haemangiomasmentioning

confidence: 99%

See 1 more Smart Citation

Extranasopharyngeal angiofibroma revisited

Windfuhr

Vent

2017

Clinical Otolaryngology

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Background Angiofibromas in the head and neck region usually arise in the nasopharynx, but may also occur elsewhere. This study aims at evaluating the incidence and clinical features of extranasopharyngeal angiofibroma (ENA). Material and Methods Systematic review of the literature (Medline® and Google™) up to 31 December 2015. Results 174 cases of ENA were retrieved from a total of 170 publications. In contrast to former publications and previous understanding, the nasal septum was by far the most common site of the disease. Four patients had a congenital lesion, the oldest patient was 87 years old (mean: 28.7 years; median: 23 years). Male gender was predominantly affected, but the sex ratio was more balanced (2.13:1) than in previous reports in the literature until 12/2015. The majority of patients presented with nasal obstruction, either in combination with epistaxis (25.8%) or other symptoms (12.6%). Symptoms had developed within 13.1 months on average (median: 4 months). Brisk bleeding resulted in 11 of 43 biopsy procedures. Surgical resection as first‐line therapy was performed in 170 patients. A tumour regrowth within 12 months was registered in four patients. Conclusion The increasing awareness of ENA and the willingness to publish case reports—not only in Medline‐listed journals—resulted in a significant increase of published case reports lately. Although extremely rare, ENAs have to be taken into account in the differential diagnosis of unclear masses, particularly in adult patients presenting with a rapidly developing nasal obstruction resulting from a nasal septum tumour. Female gender or normal vascularity does not exclude the diagnosis. Transnasal resection is sufficient in most cases, and recurrences are rare. Pathologists as well as clinicians should consider ENA in their differential diagnosis of any mass of the upper airway.

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Section: Discussionmentioning

confidence: 99%

Section: Haemangiomasmentioning

confidence: 99%

Extranasopharyngeal angiofibroma revisited

Windfuhr

Vent

2017

Clinical Otolaryngology

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“…They most commonly originate from the maxillary sinus. Other rare sites reported are the ethmoid and sphenoid sinuses, nasal septum, middle turbinate, inferior turbinates, conjunctiva, molar and retromolar region, tonsil, and larynx [2, 5, 6]. Unlike nasopharyngeal angiofibromas, extranasopharyngeal angiofibromas occur more frequently in females at later age [1].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Location of Juvenile Angiofibroma: A Case Report and Review of the Literature

Maheshwarappa

Gupta

Bansal

et al. 2013

Case Reports in Otolaryngology

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A 10-year-old boy presented with left-sided nasal obstruction and epistaxis. Endoscopic evaluation revealed a polypoid mass in the vestibule arising from the lateral wall of the nasal cavity anteroinferior to the left inferior turbinate. Computed tomography (CT) scan showed a soft tissue opacity in the vestibule of the left nasal cavity. After the endoscopic excision of the mass, postoperative and histopathological analyses confirmed the diagnosis of an angiofibroma.

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“…Etiology for extranasopharyngeal angiofi broma is due to ectopic tissue which may be located G. S. Renukananda ( ) The patients who have different characteristic other than classical angiofi broma may be called atypical angiofi broma, under the scope of the related literature. Angiofi broma presenting with at least one of the following criteria such as origin or location other than nasopharynx, presenting complains other than nasal obstruction or epistaxis, age younger than seven or older than 25, female sex, atypical histopathology and multifocality were considered as a typical [4].…”

Section: Discussionmentioning

confidence: 99%