Attenuated relationship between cardiac output and oxygen uptake during high‐intensity exercise

Abstract

The observation that the rate of increase in CO is reduced as exercise intensity increases suggests that cardiovascular performance displays signs of compromised function before maximal VO(2) is reached.

Prior exercise training alleviates the lung inflammation induced by subsequent exposure to environmental cigarette smoke

“…Additionally, CS also induces epithelial repairing and mucus hypersecretion (Maestrelli et al 2001, Essers et al 2005, Voynow & Rubin 2009). Physical exercise is known to provide beneficial effects on physiological function or various forms of inflammatory diseases through different molecular mechanism (Pedersen et al 1998, Piepoli et al 2001, Kemi & Wisløff 2010, Trinity et al 2012. Therefore, the findings from our study and other reports suggest that the benefits of exercise training on the CS-induced inflammation may be attributed to the down-regulation of these diverse multiple pathways.…”

“…, Trinity et al . ). Therefore, the findings from our study and other reports suggest that the benefits of exercise training on the CS‐induced inflammation may be attributed to the down‐regulation of these diverse multiple pathways.…”

Changes in Total Cardiac Output and Oxygen Extraction During Exercise in Patients Supported With an HVAD Left Ventricular Assist Device

“…The literature shows that in healthy persons avDO 2 at rest is between 5 and 6 mL/dL (about 33% of oxygen content) and can increase at maximum exercise to values between 14 and 18 mL/dL (up to 80% of oxygen content), dependent on factors such as training condition .…”

Oxygen Sensing, Uptake, Delivery, Consumption and Related Disorders

“…Obviously, oxygen is a key in energy metabolism (Balestra & Germonpre 2011, Wang 2011, Trinity et al 2012, and ventilation requires balancing between oxygen demand and CO 2 elimination (Nisell 2011), the latter is coupled with pH control. Obviously, oxygen is a key in energy metabolism (Balestra & Germonpre 2011, Wang 2011, Trinity et al 2012, and ventilation requires balancing between oxygen demand and CO 2 elimination (Nisell 2011), the latter is coupled with pH control.…”

“…Acta Physiologica (Oxford) has a long tradition in publishing key articles on oxygen sensing, oxygen handling and their disorders. Obviously, oxygen is a key in energy metabolism (Balestra & Germonpre 2011, Wang 2011, Trinity et al 2012, and ventilation requires balancing between oxygen demand and CO 2 elimination (Nisell 2011), the latter is coupled with pH control. This coupling of two critical physiological processes, oxygen uptake and pH control, is an issue on its own and only one aspect of a highly complex, and yet not fully understood, regulatory machinery that controls physiological adaptations to alterations in the metabolic rate as well as the environment (Moriondo et al 2011).…”